Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Vincent Pennaneach"'
Autor:
Melissa Leriche, Clara Bonnet, Jagannath Jana, Gita Chhetri, Sabrina Mennour, Sylvain Martineau, Vincent Pennaneach, Didier Busso, Xavier Veaute, Pascale Bertrand, Sarah Lambert, Kumar Somyajit, Patricia Uguen, Stéphan Vagner
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113412- (2023)
Summary: RNA-binding proteins (RBPs) are found at replication forks, but their direct interaction with DNA-embedded RNA species remains unexplored. Here, we report that p53-binding protein 1 (53BP1), involved in the DNA damage and replication stress
Externí odkaz:
https://doaj.org/article/1d3d195f8aeb42279264487ea3a2ec76
Autor:
Laetitia Besse, Typhaine Rumiac, Anne Reynaud-Angelin, Cédric Messaoudi, Marie-Noëlle Soler, Sarah A.E. Lambert, Vincent Pennaneach
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102446- (2023)
Summary: Here, we present a protocol for multivariate quantitative-image-based cytometry (QIBC) analysis by fluorescence microscopy of asynchronous adherent cells. We describe steps for the preparation, treatment, and fixation of cells, sample staini
Externí odkaz:
https://doaj.org/article/2c436cd49b5a4495832779e261c45392
Autor:
Vincent Pennaneach, Richard D Kolodner
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6389 (2009)
The gross chromosomal rearrangements (GCRs) observed in S. cerevisiae mutants with increased rates of accumulating GCRs include predicted dicentric GCRs such as translocations, chromosome fusions and isoduplications. These GCRs resemble the genome re
Externí odkaz:
https://doaj.org/article/22314ff81d5240e485a9bd4690713500
Autor:
Janet Hall, Bernard S. Lopez, Josée Guirouilh-Barbat, Alexis Fouquin, Vincent Pennaneach, Mounira Amor-Guéret
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (21), pp.12325-12339. ⟨10.1093/nar/gkx881⟩
Nucleic Acids Research, Oxford University Press, 2017, 45 (21), pp.12325-12339. ⟨10.1093/nar/gkx881⟩
International audience; Double strand breaks (DSBs) are one of the most toxic lesions to cells. DSB repair by the canonical non-homologous end-joining (C-EJ) pathway involves minor, if any, processing of the broken DNA-ends, whereas the initiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5abc9bb1744600b8da7d900349c0149
https://hal.archives-ouvertes.fr/hal-03048269
https://hal.archives-ouvertes.fr/hal-03048269
Autor:
Frédérique Mégnin-Chanet, Alain Fourquet, Janet Hall, Youlia M. Kirova, V. Pernin, Vincent Pennaneach
Publikováno v:
Cancer/Radiothérapie. 18:790-798
Resume La poly-ADP-ribosylation, assuree par les proteines de la famille des poly(ADP-ribose)polymerases (PARP), correspond a une modification post-traductionnelle de proteines impliquees dans la regulation de plusieurs processus cellulaires. Parmi l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0e90aa01bf8566a09b05de0251c756d
https://doi.org/10.1016/j.canrad.2014.05.012
https://doi.org/10.1016/j.canrad.2014.05.012
Autor:
Vincent Pennaneach, Janet Hall
Publikováno v:
The Base Excision Repair Pathway: Molecular Mechanisms and Role in Disease Development and Therapeutic Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc6e183a9287dd11ec30b0094d32d76
https://doi.org/10.1142/9789814719735_0009
https://doi.org/10.1142/9789814719735_0009
Autor:
François D. Boussin, Catherine Le Chalony, Julia Gross, Vincent Pennaneach, Laurent Gauthier, Denis Biard, Françoise Hoffschir
Publikováno v:
Cellular and Molecular Life Sciences
DNA ligase I (LigI) plays a central role in the joining of strand interruptions during replication and repair. In our current study, we provide evidence that DNA ligase III (LigIII) and XRCC1, which form a complex that functions in single-strand brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392c47e0fc797ad174fa2bb9ee81b82a
https://doi.org/10.1007/s00018-012-0975-8
https://doi.org/10.1007/s00018-012-0975-8
Autor:
Mohammed-Tayyib Boudra, Frédérique Mégnin-Chanet, Celeste Bolin, Janet Hall, Vincent Pennaneach, Vincent Favaudon, Tomasz Zaremba, Laurence Vaslin, Marie Fernet, Denis Biard, Fabrice P. Cordelières
Publikováno v:
Cellular and Molecular Life Sciences
Cyclin-dependent kinase 5 (Cdk5) has been identified as a determinant of sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors. Here, the consequences of its depletion on cell survival, PARP activity, the recruitment of base excision repair (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a39584cd875aedf18c82b6a8310204
http://europepmc.org/articles/PMC3285760
http://europepmc.org/articles/PMC3285760
Autor:
Vincent Pennaneach, Mohammed-Tayyib Boudra, Janet Hall, Charles Fouillade, Vincent Favaudon, Alexis Fouquin
Publikováno v:
Cancer Drug Discovery and Development ISBN: 9783319141503
Whilst the depletion of poly(ADP-ribose) polymerase (PARP) activity associated with PARP-1 and PARP-2 in cells causes radiosensitivity, its inhibition by small molecule inhibitors is showing great potential as a mechanism to potentiate the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d320342a5facd7b1ae426ca0704e8cdf
https://doi.org/10.1007/978-3-319-14151-0_11
https://doi.org/10.1007/978-3-319-14151-0_11
Publikováno v:
Molecular Microbiology. 59:1357-1368
The repair of spontaneous or induced DNA damage by homologous recombination (HR) in Saccharomyces cerevisiae will suppress chromosome rearrangements. Alternative chromosome healing pathways can result in chromosomal instability. One of these pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8b4875013c3671da82e4b0c0fe9678
https://doi.org/10.1111/j.1365-2958.2006.05026.x
https://doi.org/10.1111/j.1365-2958.2006.05026.x