Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Vincent Paget"'
Autor:
Ségolène Ladaigue, Vincent Paget, Anne-Charlotte Lefranc, Monica Quitoco, Emilie Bacquer, Fabien Milliat, Olivier Guipaud
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102388- (2023)
Summary: In vitro modeling of the different steps of immune cell recruitment is essential to decipher the role of endothelial cells in this process. Here, we present a protocol for the assessment of human monocyte transendothelial migration using a l
Externí odkaz:
https://doaj.org/article/cbfd0a28303c4dc58a74552f12088654
Autor:
Vincent Paget-Blanc, Marlene E. Pfeffer, Marie Pronot, Paul Lapios, Maria-Florencia Angelo, Roman Walle, Fabrice P. Cordelières, Florian Levet, Stéphane Claverol, Sabrina Lacomme, Mélina Petrel, Christelle Martin, Vincent Pitard, Véronique De Smedt Peyrusse, Thomas Biederer, David Perrais, Pierre Trifilieff, Etienne Herzog
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The neurotransmitter dopamine is an important regulator of brain function. Here the authors describe “dopamine hub synapses”, where dopamine transmission may act in synergy with other neurotransmitters.
Externí odkaz:
https://doaj.org/article/d9419129d0284637921db33ea1d13266
Autor:
Ségolène Ladaigue, Anne-Charlotte Lefranc, Khadidiatou Balde, Monica Quitoco, Emilie Bacquer, Didier Busso, Guillaume Piton, Jordane Dépagne, Nathalie Déchamps, Nao Yamakawa, Louise Debusschere, Chunxue Han, Fabrice Allain, Valérie Buard, Georges Tarlet, Agnès François, Vincent Paget, Fabien Milliat, Olivier Guipaud
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105482- (2022)
Summary: Radiation therapy damages tumors and normal tissues, probably in part through the recruitment of immune cells. Endothelial high-mannose N-glycans are, in particular, involved in monocyte-endothelium interactions. Trimmed by the class I α-ma
Externí odkaz:
https://doaj.org/article/7b3531f64b0e41c9a048f3a9df0dbcd0
Autor:
Ian Morilla, Philippe Chan, Fanny Caffin, Ljubica Svilar, Sonia Selbonne, Ségolène Ladaigue, Valérie Buard, Georges Tarlet, Béatrice Micheau, Vincent Paget, Agnès François, Maâmar Souidi, Jean-Charles Martin, David Vaudry, Mohamed-Amine Benadjaoud, Fabien Milliat, Olivier Guipaud
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103685- (2022)
Summary: The vascular endothelium is a hot spot in the response to radiation therapy for both tumors and normal tissues. To improve patient outcomes, interpretable systemic hypotheses are needed to help radiobiologists and radiation oncologists propo
Externí odkaz:
https://doaj.org/article/b44655db2d944f4da5b98c4b5f05c918
Autor:
Annaïg Bertho, Morgane Dos Santos, Sarah Braga-Cohen, Valérie Buard, Vincent Paget, Olivier Guipaud, Georges Tarlet, Fabien Milliat, Agnès François
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Lung stereotactic body radiation therapy is characterized by a reduction in target volumes and the use of severely hypofractionated schedules. Preclinical modeling became possible thanks to rodent-dedicated irradiation devices allowing accurate beam
Externí odkaz:
https://doaj.org/article/b5f4d5aadfad46eca0418e7dc3e47de7
Autor:
Cyprien Jaillet, Willy Morelle, Marie-Christine Slomianny, Vincent Paget, Georges Tarlet, Valérie Buard, Sonia Selbonne, Fanny Caffin, Emilie Rannou, Pierre Martinez, Agnès François, François Foulquier, Fabrice Allain, Fabien Milliat, Olivier Guipaud
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract As it is altered by ionizing radiation, the vascular network is considered as a prime target in limiting normal tissue damage and improving tumor control in radiation therapy. Irradiation activates endothelial cells which then participate in
Externí odkaz:
https://doaj.org/article/f9690215a646472da6218ce07771cc2c
Autor:
Elodie Mintet, Jérémy Lavigne, Vincent Paget, Georges Tarlet, Valérie Buard, Olivier Guipaud, Jean-Christophe Sabourin, Maria-Luisa Iruela-Arispe, Fabien Milliat, Agnès François
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The current study evaluated the role of Hey2 transcription factor in radiation-induced endothelial-to-mesenchymal transition (EndoMT) and its impact on radiation-induced tissue damage in mice. Phenotypic modifications of irradiated, Hey2 siR
Externí odkaz:
https://doaj.org/article/16e3d124e47b4cf3a626bb2025127e36
Autor:
Vincent Paget, Samir Dekali, Thierry Kortulewski, Romain Grall, Christelle Gamez, Kelly Blazy, Olivier Aguerre-Chariol, Sylvie Chevillard, Anne Braun, Patrice Rat, Ghislaine Lacroix
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123297 (2015)
Nanoparticle surface chemistry is known to play a crucial role in interactions with cells and their related cytotoxic effects. As inhalation is a major route of exposure to nanoparticles, we studied specific uptake and damages of well-characterized f
Externí odkaz:
https://doaj.org/article/72a4f42bd5454e2c9cf58f16d80ce4c7
Autor:
Vincent Paget, Mathilde Lechevrel, Véronique André, Jérémie Le Goff, Didier Pottier, Sylvain Billet, Guillaume Garçon, Pirouz Shirali, François Sichel
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30921 (2012)
Mutations in the TP53 gene are the most common alterations in human tumours. TP53 mutational patterns have sometimes been linked to carcinogen exposure. In hepatocellular carcinoma, a specific G>T transversion on codon 249 is classically described as
Externí odkaz:
https://doaj.org/article/67cf8bef1fc148ca87e1817fed6537ff
Autor:
Etienne Herzog, Paul Lapios, Vincent Paget-Blanc, Sabrina Lacomme, Maria-Florencia Angelo, Véronique Desmedt-Peyrusse, Stéphane Claverol, Thomas Biederer, Roman Walle, David Perrais, Vincent Pitard, Melina Petrel, Marie Pronot, Fabrice P. Cordelières, Christelle Martin, Marlene E. Pfeffer, Florian Levet, Pierre Trifilieff
SUMMARYDopamine is a monoamine involved in reward processing and motor control. Volume transmission is thought to be the mechanism by which monoamines modulate effector systems at glutamate and GABA synapses. Hence, dopamine synapses are scarcely des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23569e1cbdc30837a3062cd03baeee28
https://hal.archives-ouvertes.fr/hal-03437276
https://hal.archives-ouvertes.fr/hal-03437276