Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Vincent Pagès"'
Autor:
Katarzyna H. Masłowska, Vincent Pagès
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
DNA Damage Tolerance (DDT) functions to bypass replication-blocking lesions and is divided into two distinct pathways: error-prone Translesion Synthesis (TLS) and error-free Damage Avoidance (DA). Rad5 is a multifunctional protein that is involved in
Externí odkaz:
https://doaj.org/article/daeb7ad441dc4cb4a947453e5ec1fbb6
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010238 (2022)
During replication, the presence of unrepaired lesions results in the formation of single stranded DNA (ssDNA) gaps that need to be repaired to preserve genome integrity and cell survival. All organisms have evolved two major lesion tolerance pathway
Externí odkaz:
https://doaj.org/article/52cca27b24524a93897444ac0f6e4178
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005757 (2015)
DNA Damage Tolerance (DDT) mechanisms help dealing with unrepaired DNA lesions that block replication and challenge genome integrity. Previous in vitro studies showed that the bacterial replicase is able to re-prime downstream of a DNA lesion, leavin
Externí odkaz:
https://doaj.org/article/9915441300cf446daed0db6f5f7fb753
Autor:
Seungwoo Chang, Elizabeth S. Thrall, Luisa Laureti, Sadie C. Piatt, Vincent Pagès, Joseph J. Loparo
Publikováno v:
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology, 2022, 29 (9), pp.932+. ⟨10.1038/s41594-022-00827-2⟩
Nat Struct Mol Biol
Nature Structural & Molecular Biology, 2022, 29 (9), pp.932+. ⟨10.1038/s41594-022-00827-2⟩
Nat Struct Mol Biol
Processivity clamps tether DNA polymerases to DNA, allowing their access to the primer-template junction. In addition to DNA replication, DNA polymerases also participate in various genome maintenance activities, including translesion synthesis (TLS)
Autor:
Katarzyna Maslowska, Vincent Pagès
DNA Damage Tolerance (DDT) functions to bypass replication-blocking lesions and is divided into two distinct pathways: error-prone Translesion Synthesis (TLS) and error-free Damage Avoidance (DA).Rad5 is a a multifunctional protein that is involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88a3c843fb11905f30246f74893056f
https://doi.org/10.1101/2022.01.06.475185
https://doi.org/10.1101/2022.01.06.475185
DNA replication is mediated by the coordinated actions of multiple enzymes within replisomes. Processivity clamps tether many of these enzymes to DNA, allowing access to the primer/template junction. Many clamp-interacting proteins (CLIPs) are involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3c733889e62047a1f5044ccef6a940
https://hal.archives-ouvertes.fr/hal-03021305/document
https://hal.archives-ouvertes.fr/hal-03021305/document
Autor:
Vincent Pagès, Olivier Huet
Le handicap, qu'il soit physique, mental, psychique, cognitif, sensoriel ou polyhandicap, recouvre des réalités multiples pour les personnes touchées, ce qui implique autant de réponses différentes de la part des professionnels. La classificatio
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2019, ⟨10.1093/nar/gkz723⟩
Nucleic Acids Research, 2019, ⟨10.1093/nar/gkz723⟩
Nucleic Acids Research, Oxford University Press, 2019, ⟨10.1093/nar/gkz723⟩
Nucleic Acids Research, 2019, ⟨10.1093/nar/gkz723⟩
Genome of all living cell can be altered in several manners: DNA lesions such as abasic sites, DNA adducts, DNA crosslinks (intra- or inter-strand), DNA-protein crosslinks, presence of ribonucleotides... These damages, if not repaired will interfere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e196df0a0ad88d0946a5eac682c161
Autor:
Robert P. Fuchs, Vincent Pagès
Publikováno v:
Genome Instability Methods and Protocols
Genome Instability Methods and Protocols, 1672, pp.107-118, 2018, Methods in Molecular Biology, ⟨10.1007/978-1-4939-7306-4_9⟩
Methods in Molecular Biology
Methods in Molecular Biology, 2018, pp.107-118. ⟨10.1007/978-1-4939-7306-4_9⟩
Methods in Molecular Biology, Humana Press/Springer Imprint, 2018, pp.107-118. ⟨10.1007/978-1-4939-7306-4_9⟩
Methods in Molecular Biology ISBN: 9781493973057
Genome Instability Methods and Protocols, 1672, pp.107-118, 2018, Methods in Molecular Biology, ⟨10.1007/978-1-4939-7306-4_9⟩
Methods in Molecular Biology
Methods in Molecular Biology, 2018, pp.107-118. ⟨10.1007/978-1-4939-7306-4_9⟩
Methods in Molecular Biology, Humana Press/Springer Imprint, 2018, pp.107-118. ⟨10.1007/978-1-4939-7306-4_9⟩
Methods in Molecular Biology ISBN: 9781493973057
International audience; Here, we describe a methodology that allows the insertion of site-specific DNA lesions into genomes in living cells. The technique involves the integration of a plasmid containing a site-specific lesion engineered in vitro int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e94c9eee670b91f2f486a5bbc0945a
https://hal.archives-ouvertes.fr/hal-02145861
https://hal.archives-ouvertes.fr/hal-02145861