Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Vincent P. Willard"'
Autor:
Ruhang Tang, Liufang Jing, Vincent P. Willard, Chia-lung Wu, Farshid Guilak, Jun Chen, Lori A. Setton
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background Intervertebral disc (IVD) degeneration is characterized by an early decrease in cellularity of the nucleus pulposus (NP) region, and associated extracellular matrix changes, reduced hydration, and progressive degeneration. Cell-ba
Externí odkaz:
https://doaj.org/article/11b5e4d701e74f959d7918880ac5509a
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1202-1213 (2017)
Chronic inflammatory diseases such as arthritis are characterized by dysregulated responses to pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor α (TNF-α). Pharmacologic anti-cytokine therapies are often effective at
Externí odkaz:
https://doaj.org/article/3c34272b39464b89b769fe08f5f94276
Autor:
Wolfgang Liedtke, Daniel Palmer, Holly A. Leddy, Chia-Lung Wu, Vincent P. Willard, Farshid Guilak
Publikováno v:
Stem Cells
Transient receptor potential vanilloid 4 (TRPV4) is a polymodal calcium-permeable cation channel that is highly expressed in cartilage and is sensitive to a variety of extracellular stimuli. The expression of this channel has been associated with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a890f56518750a4d03d448951b37857
https://doi.org/10.1002/stem.3440
https://doi.org/10.1002/stem.3440
Autor:
Karl Schuchard, Behnam Pourdeyhimi, Vincent P. Willard, Bruce Anderson, Abhay Joijode, Pierre Grondin, Rohan A. Shirwaiker
Publikováno v:
Procedia Manufacturing. 53:128-135
Biocompatible polymer fibers have garnered significant interest due to their unique properties. Applications range from absorbent media to tissue engineering and drug delivery products. Many manufacturing processes produce such fibers, but a gap exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc67a34dae9620d28189fdbb7cfd1e67
https://doi.org/10.1016/j.promfg.2021.06.017
https://doi.org/10.1016/j.promfg.2021.06.017
Autor:
Bradley T. Estes, Megan A. Carson, Jonathan W. Stallrich, Franklin T. Moutos, Vincent P. Willard, Deborah J. Veis, Masataka Enomoto, Jeffrey M. Toth, B. Duncan X. Lascelles, Peter Eggert, Dianne Little, Farshid Guilak
Publikováno v:
Science advances. 7(38)
Articular cartilage has unique load-bearing properties but has minimal capacity for intrinsic repair. Here, we used three-dimensional weaving, additive manufacturing, and autologous mesenchymal stem cells to create a tissue-engineered, bicomponent im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad35bdbfb6b5b9ad9a9158475f78b1cd
https://pubmed.ncbi.nlm.nih.gov/34524840
https://pubmed.ncbi.nlm.nih.gov/34524840
Autor:
Charles A. Gersbach, Shaunak S. Adkar, Jonathan M. Brunger, Farshid Guilak, Chia-Lung Wu, Vincent P. Willard
Publikováno v:
Trends in Molecular Medicine. 23:917-931
Arthritis represents a family of complex joint pathologies responsible for the majority of musculoskeletal conditions. Nearly all diseases within this family, including osteoarthritis, rheumatoid arthritis, and juvenile idiopathic arthritis, are chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed363c28af290baea1d3601788e98721
https://doi.org/10.1016/j.molmed.2017.08.002
https://doi.org/10.1016/j.molmed.2017.08.002
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1202-1213 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Chronic inflammatory diseases such as arthritis are characterized by dysregulated responses to pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor α (TNF-α). Pharmacologic anti-cytokine therapies are often effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe34eaf93ded9ebec8bd8c68c231a626
http://www.sciencedirect.com/science/article/pii/S2213671117301285
http://www.sciencedirect.com/science/article/pii/S2213671117301285
Autor:
Shaunak S. Adkar, Adarsh R. Ettyreddy, Vincent P. Willard, Nidhi Bhutani, Amanda Dicks, Chia-Lung Wu, Charles A. Gersbach, Farshid Guilak, Nancy Steward
The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and drug s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3a5cbe95a183b75e0cc26e2ef2d1ed
https://europepmc.org/articles/PMC6312762/
https://europepmc.org/articles/PMC6312762/
Autor:
Shaunak S. Adkar, Ettyreddy A, Cathy H. Wu, Nancy Steward, Nidhi Bhutani, Charles A. Gersbach, Dicks Ar, Farshid Guilak, Vincent P. Willard
SummaryThe differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961ab6aabf0026a2282f4fed3c599be7
Autor:
Johannah Sanchez-Adams, Brian O. Diekman, Nicolas Christoforou, Vincent P. Willard, Farshid Guilak, Kam W. Leong
Publikováno v:
Arthritis & Rheumatology. 66:3062-3072
Objective The discovery of novel disease-modifying drugs for osteoarthritis (OA) is limited by the lack of adequate genetically defined cartilage tissues for application in high-throughput screening systems. We addressed this need by synthesizing car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e88100ff9fc1bbfa8bf79b7b74766c2
https://doi.org/10.1002/art.38780
https://doi.org/10.1002/art.38780