Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Vincent Ollendorff"'
Autor:
Nathalie Bouquier, Enora Moutin, Lionel A. Tintignac, Amandine Reverbel, Elodie Jublanc, Michael Sinnreich, Yan Chastagnier, Julien Averous, Pierre Fafournoux, Chiara Verpelli, Tobias Boeckers, Gilles Carnac, Julie Perroy, Vincent Ollendorff
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background mTOR signaling is an essential nutrient and energetic sensing pathway. Here we describe AIMTOR, a sensitive genetically encoded BRET (Bioluminescent Resonance Energy Transfer) biosensor to study mTOR activity in living cells. Resu
Externí odkaz:
https://doaj.org/article/de858ec3955d4d94a438dc5be235f72e
Publikováno v:
Bio-Protocol, Vol 11, Iss 8 (2021)
Mammalian target of rapamycin (mTOR) controls many crucial cellular functions, including protein synthesis, cell size, energy metabolism, lysosome and mitochondria biogenesis, and autophagy. Consequently, deregulation of mTOR signaling plays a role i
Externí odkaz:
https://doaj.org/article/05cafa68ac414ffaa27de3fa5e5e9fa5
Autor:
Florian A. Britto, Fabienne Cortade, Yassine Belloum, Marine Blaquière, Yann S. Gallot, Aurélie Docquier, Allan F. Pagano, Elodie Jublanc, Nadia Bendridi, Christelle Koechlin-Ramonatxo, Béatrice Chabi, Marc Francaux, François Casas, Damien Freyssenet, Jennifer Rieusset, Sophie Giorgetti-Peraldi, Gilles Carnac, Vincent Ollendorff, François B. Favier
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently recognized as a negative regulator of muscle mass through inhibition of the Akt/m
Externí odkaz:
https://doaj.org/article/fec9c00871564efe8cdbac8f34f294b2
Autor:
Raphaële Thiébaut, Sophie Esmiol, Patrick Lecine, Batoul Mahfouz, Aurelie Hermant, Cendrine Nicoletti, Stephane Parnis, Julie Perroy, Jean-Paul Borg, Leigh Pascoe, Jean-Pierre Hugot, Vincent Ollendorff
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165420 (2016)
NOD2 contributes to the innate immune response and to the homeostasis of the intestinal mucosa. In response to its bacterial ligand, NOD2 interacts with RICK and activates the NF-κB and MAPK pathways, inducing gene transcription and synthesis of pro
Externí odkaz:
https://doaj.org/article/d104d6b8fb8349ca8fc5fa70f2f07371
Autor:
Waed Abdel Khalek, Fabienne Cortade, Vincent Ollendorff, Laure Lapasset, Lionel Tintignac, Béatrice Chabi, Chantal Wrutniak-Cabello
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114388 (2014)
Sirtuin 3 (SIRT3), one of the seven mammalian sirtuins, is a mitochondrial NAD+-dependent deacetylase known to control key metabolic pathways. SIRT3 deacetylases and activates a large number of mitochondrial enzymes involved in the respiratory chain,
Externí odkaz:
https://doaj.org/article/f08bb3b5cf6d4cb58ca304cab8391558
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84569 (2013)
BACKGROUND: Nuclear receptors (NR) regulate transcription of genes involved in many biological processes such as development, cell proliferation, differentiation and cell death. Amongst them, PPARG2 and THR control tissue glucose and lipid homeostasi
Externí odkaz:
https://doaj.org/article/4d6e57a0faba4ecc871dc3bb48919436
Autor:
Ulrich Meinzer, Sophie Esmiol-Welterlin, Frederick Barreau, Dominique Berrebi, Monique Dussaillant, Stephane Bonacorsi, Fabrice Chareyre, Michiko Niwa-Kawakita, Corinne Alberti, Ghislaine Sterkers, Claude Villard, Thecla Lesuffleur, Michel Peuchmaur, Michael Karin, Lars Eckmann, Marco Giovannini, Vincent Ollendorff, Hans Wolf-Watz, Jean-Pierre Hugot
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2769 (2008)
Nucleotide oligomerisation domain 2 (NOD2) is a component of the innate immunity known to be involved in the homeostasis of Peyer patches (PPs) in mice. However, little is known about its role during gut infection in vivo. Yersinia pseudotuberculosis
Externí odkaz:
https://doaj.org/article/1e13e916d8c84a198cf5492130e8020a
Autor:
Frédérick Barreau, Ulrich Meinzer, Fabrice Chareyre, Dominique Berrebi, Michiko Niwa-Kawakita, Monique Dussaillant, Benoit Foligne, Vincent Ollendorff, Martine Heyman, Stéphane Bonacorsi, Thecla Lesuffleur, Ghislaine Sterkers, Marco Giovannini, Jean-Pierre Hugot
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e523 (2007)
BackgroundCARD15/NOD2 mutations are associated with susceptibility to Crohn's Disease (CD) and Graft Versus Host Disease (GVHD). CD and GVHD are suspected to be related with the dysfunction of Peyer's patches (PP) and isolated lymphoid follicles (LFs
Externí odkaz:
https://doaj.org/article/c3ebafde5ed74436ace188048b9de8fa
Autor:
Florian Britto, Karine Dumas, Vincent Ollendorff, Sophie Giorgetti-Peraldi, François Bertrand Favier
Publikováno v:
American Journal of Physiology-Cell Physiology
American Journal of Physiology-Cell Physiology, American Physiological Society, 2020, 319 (5), pp.C807-C824. ⟨10.1152/ajpcell.00340.2020⟩
American Journal of Physiology-Cell Physiology, American Physiological Society, 2020, 319 (5), pp.C807-C824. ⟨10.1152/ajpcell.00340.2020⟩
The Akt/mechanistic target of rapamycin (mTOR) signaling pathway governs macromolecule synthesis, cell growth, and metabolism in response to nutrients and growth factors. Regulated in development and DNA damage response (REDD)1 is a conserved and ubi
Autor:
Lionel Tintignac, Elodie Jublanc, Enora Moutin, Nathalie Bouquier, Julien Averous, Yan Chastagnier, Michael Sinnreich, Amandine Reverbel, Chiara Verpelli, Vincent Ollendorff, Gilles Carnac, Tobias M. Boeckers, Julie Perroy, Pierre Fafournoux
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-17 (2020)
BMC Biology
BMC Biology, 2020, 18 (1), pp.81. ⟨10.1186/s12915-020-00790-8⟩
BMC Biology, BioMed Central, 2020, 18 (1), pp.81. ⟨10.1186/s12915-020-00790-8⟩
BMC Biology
BMC Biology, 2020, 18 (1), pp.81. ⟨10.1186/s12915-020-00790-8⟩
BMC Biology, BioMed Central, 2020, 18 (1), pp.81. ⟨10.1186/s12915-020-00790-8⟩
BackgroundmTOR signaling is an essential nutrient and energetic sensing pathway. Here we describe AIMTOR, a sensitive genetically encoded BRET (Bioluminescent Resonance Energy Transfer) biosensor to study mTOR activity in living cells.ResultsAs a pro