Acid-Responsive Decomposable Nanomedicine Based on Zeolitic Imidazolate Frameworks for Near-Infrared Fluorescence Imaging/Chemotherapy Combined Tumor Theranostics

Autor: Heze Guo, Vincent Mukwaya, Daikun Wu, Shuhan Xiong, Hongjing Dou

Publikováno v: Pharmaceutics, Vol 16, Iss 6, p 823 (2024)

Zeolitic imidazolate framework-8 (ZIF-8) nanoparticles (NPs) are gaining traction in tumor theranostics for their effectiveness in encapsulating both imaging agents and therapeutic drugs. While typically, similar hydrophilic molecules are encapsulate

Externí odkaz: https://doaj.org/article/79cfc0ef9a204869aa8bc79040415667

Polysaccharide/Lipid Nanoconjugates as Alternative Building Blocks for Highly Biocompatible Microcapsules

Autor: Jackeline Soto-Cruz, Vincent Mukwaya, Mehwish Naz, Peipei Zhang, María José López-Brenes, Giovanni Sáenz-Arce, Oscar Rojas-Carrillo, Hongjing Dou

Publikováno v: Langmuir. 38:9556-9566

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a1b97ae0f679fd0821bbd0a173bc8d1
https://doi.org/10.1021/acs.langmuir.2c00937

Chemical communication at the synthetic cell/living cell interface

Autor: Stephen Mann, Hongjing Dou, Vincent Mukwaya

Publikováno v: Communications Chemistry, Vol 4, Iss 1, Pp 1-12 (2021)

Although the complexity of synthetic cells has continued to increase in recent years, chemical communication between protocell models and living organisms remains a key challenge in bottom-up synthetic biology and bioengineering. In this Review, we d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48eff9d6bd3df6a6210812f356a7322c
https://doaj.org/article/9fe0be548cc240589b2ac5328c69c142

Lectin-Glycan-Mediated Nanoparticle Docking as a Step toward Programmable Membrane Catalysis and Adhesion in Synthetic Protocells

Autor: Vincent Mukwaya, Qiangqiang Hu, Heze Guo, Auphedeous Yinme Dang-i, Hongjing Dou, Stephen Mann, Mei Li, Peipei Zhang

Publikováno v: Mukwaya, V, Zhang, P, Guo, H, Dang-i, A Y, Hu, Q, Li, M, Mann, S & Dou, H 2020, ' Lectin-Glycan-Mediated Nanoparticle Docking as a Step toward Programmable Membrane Catalysis and Adhesion in Synthetic Protocells ', ACS Nano, vol. 14, no. 7, pp. 7899–7910 . https://doi.org/10.1021/acsnano.0c02127

The spontaneous assembly of nanoscale building blocks into continuous semipermeable membranes is a key requirement for the structuration of synthetic protocells. Engineering the functionality and programmability of these building units provides a ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a58acbcb23c30911d3e3ebd517779fe
https://research-information.bris.ac.uk/ws/files/312037724/ACS_Nano_nn_2020_021273_MT_Plain_text_20200429.pdf

Hybrid Dextran-gadolinium Nano-suitcases as High-relaxivity MRI Contrast Agents

Autor: Qing Lu, Hongjing Dou, Shengli Li, Tingting Dai, Hao Wang, Vincent Mukwaya, Bolun Lu

Publikováno v: Chinese Journal of Polymer Science. 36:391-398

Dextran-poly(glycidyl methacrylate) (Dex-PGMA) nano-suitcases were synthesized efficiently via a graft copolymerization induced self-assembly (GISA) approach. On this basis, the Dex-PGMA nano-suitcases were modified with hydrazide, and the attachment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2d0224eed7e45d5f5a0c4962d874d01
https://doi.org/10.1007/s10118-018-2083-1