Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Vincent M. Mann"'
Autor:
Leanne K. Archer, Fiona M. Frame, Hannah F. Walker, Alastair P. Droop, Georgina L. K. McDonald, Samuel Kucko, Daniel M. Berney, Vincent M. Mann, Matthew S. Simms, Norman J. Maitland
Publikováno v:
FEBS Open Bio, Vol 12, Iss 7, Pp 1365-1387 (2022)
This study aimed to elucidate the role of ELF3, an ETS family member in normal prostate growth and prostate cancer. Silencing ELF3 in both benign prostate (BPH‐1) and prostate cancer (PC3) cell lines resulted in decreased colony‐forming ability,
Externí odkaz:
https://doaj.org/article/aa77d4e3bca64e6fbadf19f5700541d1
Autor:
Conor M. Devlin, Fiona M. Frame, Leanne K. Archer, Vincent M. Mann, Hannah Walker, Matthew S. Simms, Daniel M. Berney, Anne T. Collins, Norman J. Maitland
Publikováno v:
European Urology Open Science, Vol 21, Iss , Pp 29-32 (2020)
Externí odkaz:
https://doaj.org/article/2769066dae164640bd16b32114735e25
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
Interleukin (IL)-6 overexpression and constitutive STAT3 activation occur in many cancers, including prostate cancer. However, their contribution to prostate stem and progenitor cells has not been explored. In this study, we show that stem-like cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3759079a1cd74807e03543c8d654275f
https://doi.org/10.1158/0008-5472.c.6506609
https://doi.org/10.1158/0008-5472.c.6506609
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
PDF file, 8K, 3.mRNA expression of IL-6 (fold change) in prostatic primary cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfe8b03c975ddbe5c5743ba5a98750d
https://doi.org/10.1158/0008-5472.22404452
https://doi.org/10.1158/0008-5472.22404452
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
PDF file, 84K, 4.IL-6 levels (pg/ml/103 cells) in the supernatant of prostatic primary cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6002e5aeeb9c48dc8c76fa3608fa0c
https://doi.org/10.1158/0008-5472.22404449.v1
https://doi.org/10.1158/0008-5472.22404449.v1
Autor:
Anne T. Collins, Norman J. Maitland, Pui-Kai Li, Chenglong Li, Somsundaram Chettiar, Deepak Bhasin, Matthew Simms, Vincent M. Mann, Greta Rodrigues, Michael J. Stower, Paul A. Berry, Paula Kroon
PDF file, 7896K, A. Histology of mouse xenograft. H&E stain of a mouse xenograft derived from a patient with castrate-resistant prostate cancer. Small glandular structures are apparent with large, prominent nucleoli within sheets of undifferentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b53d35697d0aaec54104f3fe6aec43
https://doi.org/10.1158/0008-5472.22404455.v1
https://doi.org/10.1158/0008-5472.22404455.v1
Autor:
Vincent M. Mann, Norman J. Maitland, Fiona M. Frame, Conor M Devlin, Leanne K. Archer, Hannah F. Walker, Daniel M. Berney, Matthew S. Simms, Anne T. Collins
Publikováno v:
European Urology Open Science, Vol 21, Iss, Pp 29-32 (2020)
European Urology Open Science
European Urology Open Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc0513e7de1936f6a82c260261f996e
http://www.sciencedirect.com/science/article/pii/S2666168320351430
http://www.sciencedirect.com/science/article/pii/S2666168320351430
Autor:
Vincent M. Mann, Rachel Adamson, Fiona M. Frame, Deborah O'Connell, John R. Packer, Norman J. Maitland, Matthew S. Simms, Alastair Droop, Adam M. Hirst
Publikováno v:
Febs Letters
Low Temperature Plasma (LTP) generates reactive oxygen and nitrogen species, causing cell death, similarly to radiation. Radiation resistance results in tumour recurrence, however mechanisms of LTP resistance are unknown. LTP was applied to patient-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341d0f4e89b092696e428c035b64ce1c
https://doi.org/10.1002/1873-3468.13589
https://doi.org/10.1002/1873-3468.13589
Autor:
Engin Ulukaya, Fiona M Frame, Buse Cevatemre, Davide Pellacani, Hannah Walker, Vincent M Mann, Matthew S Simms, Michael J Stower, Veysel T Yilmaz, Norman J Maitland
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64278 (2013)
The outcome for patients with advanced metastatic and recurrent prostate cancer is still poor. Therefore, new chemotherapeutics are required, especially for killing cancer stem cells that are thought to be responsible for disease recurrence. In this
Externí odkaz:
https://doaj.org/article/fa2ab04b61094a7daa200d16cc8d7ccd
Autor:
Connie J. Eaves, Fiona M. Frame, Vincent M. Mann, Norman J. Maitland, Alastair Droop, Davide Pellacani, Anne T. Collins, Matthew S. Simms
Publikováno v:
British Journal of Cancer
BACKGROUND: Human prostate cancers display numerous DNA methylation changes compared to normal tissue samples. However, definitive identification of features related to the cells' malignant status has been compromised by the predominance of cells wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5814d909e20006d432895eb63c55f7d4
https://doi.org/10.1038/s41416-018-0236-1
https://doi.org/10.1038/s41416-018-0236-1