Zobrazeno 1 - 10
of 807
pro vyhledávání: '"Vincent M. Rotello"'
Autor:
Ritabrita Goswami, Ahmed Nabawy, Mingdi Jiang, Yagiz Anil Cicek, Muhammad Aamir Hassan, Harini Nagaraj, Xianzhi Zhang, Vincent M Rotello
Publikováno v:
Nanomaterials, Vol 14, Iss 19, p 1556 (2024)
Macrophages are multifunctional immune cells essential for both innate and adaptive immune responses. Tumor-associated macrophages (TAMs) often adopt a tumor-promoting M2-like phenotype, aiding tumor progression and immune evasion. Reprogramming TAMs
Externí odkaz:
https://doaj.org/article/17c59ce7361b46de80165e209ee178a3
Publikováno v:
ACS Nanoscience Au, Vol 4, Iss 1, Pp 62-68 (2023)
Externí odkaz:
https://doaj.org/article/9d8107f29f0e4595b45ed629a7f7a987
Autor:
Changjoon Keum, Cristina-Maria Hirschbiegel, Soham Chakraborty, Soyeong Jin, Youngdo Jeong, Vincent M. Rotello
Publikováno v:
Nano Convergence, Vol 10, Iss 1, Pp 1-41 (2023)
Abstract Nanozymes mimic the function of enzymes, which drive essential intracellular chemical reactions that govern biological processes. They efficiently generate or degrade specific biomolecules that can initiate or inhibit biological processes, r
Externí odkaz:
https://doaj.org/article/c0dfabc847374e8cb3a571b4fefa8855
Autor:
Liang Liu, Xianzhi Zhang, Stefano Fedeli, Yagiz Anil Cicek, William Ndugire, Vincent M. Rotello
Publikováno v:
Materials, Vol 17, Iss 7, p 1507 (2024)
Bio-orthogonal chemistry provides a powerful tool for drug delivery systems due to its ability to generate therapeutic agents in situ, minimizing off-target effects. Bio-orthogonal transition metal catalysts (TMCs) with stimuli-responsive properties
Externí odkaz:
https://doaj.org/article/67c8d3b2d07b42e38f564fd518357ad2
Autor:
Vincent M. Rotello
Publikováno v:
BME Frontiers, Vol 4 (2023)
Multidrug-resistant bacterial infections represent a dire threat to global health. The development of antibiotic resistance in bacteria coupled with the lack of development of new antibiotics is creating infections requiring antibiotics of last resor
Externí odkaz:
https://doaj.org/article/8cd1275c1c114b6bac482edc9375a85e
Autor:
Jungmi Park, Neel Mahida, Gabrielle Ho, Elizabeth Pena, Jessa Marie V. Makabenta, Stanley Aneke, Mingdi Jiang, Leah M. Bouthillette, Stephanie E. Holz, Muhammad Aamir Hassan, Amanda L. Wolfe, Vincent M. Rotello
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1240 (2023)
Multi-drug-resistant (MDR) bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), pose a significant challenge in healthcare settings. Small molecule antimicrobials (SMAs) such as α-pyrones have shown promise as alternative treatmen
Externí odkaz:
https://doaj.org/article/8f44b28528ae4c819935c5f3f0cb3037
Autor:
Sanjana Gopalakrishnan, Aarohi Gupta, Dorcas Matuwana, John J. Amante, Cathal J. Kearney, Vincent M. Rotello
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101909- (2022)
Applications involving ultrasound treatment as a therapeutic strategy have gained interest due to its enhanced tissue penetration, broad availability, and minimal invasiveness. Recently, ultrasound treatment has been utilized for applications such as
Externí odkaz:
https://doaj.org/article/933b07a4378b43898fedcb32347733b3
Autor:
Ritabrita Goswami, Victor Lehot, Yağız Anıl Çiçek, Harini Nagaraj, Taewon Jeon, Terry Nguyen, Stefano Fedeli, Vincent M. Rotello
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 218 (2023)
Current intracellular protein delivery strategies face the challenge of endosomal entrapment and consequent degradation of protein cargo. Methods to efficiently deliver proteins directly to the cytosol have the potential to overcome this hurdle. Here
Externí odkaz:
https://doaj.org/article/7713916ca44f400e8971b1793a31cd04
Autor:
Cristina-Maria Hirschbiegel, Stefano Fedeli, Xianzhi Zhang, Rui Huang, Jungmi Park, Yisheng Xu, Vincent M. Rotello
Publikováno v:
Materials, Vol 15, Iss 18, p 6487 (2022)
Bioorthogonal chemistry introduces nonbiogenic reactions that can be performed in biological systems, allowing for the localized release of therapeutic agents. Bioorthogonal catalysts can amplify uncaging reactions for the in situ generation of thera
Externí odkaz:
https://doaj.org/article/08e8be729da1441892ecfd6216315220
Autor:
P. N. Navya, Anubhav Kaphle, S. P. Srinivas, Suresh Kumar Bhargava, Vincent M. Rotello, Hemant Kumar Daima
Publikováno v:
Nano Convergence, Vol 6, Iss 1, Pp 1-30 (2019)
Abstract Nanotechnology has the potential to circumvent several drawbacks of conventional therapeutic formulations. In fact, significant strides have been made towards the application of engineered nanomaterials for the treatment of cancer with high
Externí odkaz:
https://doaj.org/article/10ecdf9068804198b775ff9429a3263e