Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Vincent Lok"'
Autor:
Stephan Brenner, Vincent Lok
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background In Germany, the 2015 mass displacement and resulting population migration exposed regulatory and structural shortcomings with respect to refugee healthcare provision. Existing research on Germany’s crisis response has largely fo
Externí odkaz:
https://doaj.org/article/6a81eca0fc4642c38d9cf0ca09415e70
Autor:
Evan R. Abt, Khalid Rashid, Thuc M. Le, Suwen Li, Hailey R. Lee, Vincent Lok, Luyi Li, Amanda L. Creech, Amanda N. Labora, Hanna K. Mandl, Alex K. Lam, Arthur Cho, Valerie Rezek, Nanping Wu, Gabriel Abril-Rodriguez, Ethan W. Rosser, Steven D. Mittelman, Willy Hugo, Thomas Mehrling, Shanta Bantia, Antoni Ribas, Timothy R. Donahue, Gay M. Crooks, Ting-Ting Wu, Caius G. Radu
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Purine nucleoside phosphorylase (PNP) enables the breakdown and recycling of guanine nucleosides. PNP insufficiency in humans is paradoxically associated with both immunodeficiency and autoimmunity, but the mechanistic basis for these outcomes is inc
Externí odkaz:
https://doaj.org/article/e438254920ee4e73ba0fa35c8e36bf84
Autor:
Christina Ip, King Sum Luk, Vincent Lok Cheung Yuen, Lorraine Chiang, Ching Ki Chan, Kevin Ho, Mengqi Gong, Teddy Tai Loy Lee, Keith Sai Kit Leung, Leonardo Roever, George Bazoukis, Konstantinos Lampropoulos, Ka Hou Christien Li, Gary Tse, Tong Liu
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 37, Iss , Pp 100887- (2021)
Objectives: Soluble suppression of tumorigenicity 2 (sST2) is a member of the interleukin-1 receptor family. It is raised in various cardiovascular diseases, but its value in predicting disease severity or mortality outcomes has been controversial. T
Externí odkaz:
https://doaj.org/article/069c23fe9ada4e4fb305c9cd4f053606
Autor:
Michael L. Steinberg, Kathleen Nguyen, Vinayak Muralidhar, Neil R. Parikh, Vincent Lok, Ting Martin Ma, Ida Sonni, Andrei Gafita, Pan Thin, David Elashoff, Johannes Czernin, Ricky Savjani, Matthew Rettig, Jesus E. Juarez, Jie Deng, Tristan Grogan, David Shabsovich, Amar U. Kishan, Patrick A. Kupelian, David D. Yang, Jeremie Calais, Nicholas G. Nickols, Carissa Chu, Felix Y. Feng, Wesley R Armstrong, Robert E. Reiter
Publikováno v:
Eur Urol Oncol
European urology oncology, vol 5, iss 1
European urology oncology, vol 5, iss 1
Prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) is an emerging imaging modality with greater sensitivity and specificity over conventional imaging for prostate cancer (PCa) staging. Using data fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2641c06c641ca2b0573c6a4e1e6db325
https://doi.org/10.1016/j.euo.2021.01.006
https://doi.org/10.1016/j.euo.2021.01.006
Autor:
Evan R. Abt, Thuc M. Le, Amanda M. Dann, Joseph R. Capri, Soumya Poddar, Vincent Lok, Luyi Li, Keke Liang, Amanda L. Creech, Khalid Rashid, Woosuk Kim, Nanping Wu, Jing Cui, Arthur Cho, Hailey Rose Lee, Ethan W. Rosser, Jason M. Link, Johannes Czernin, Ting-Ting Wu, Robert Damoiseaux, David W. Dawson, Timothy R. Donahue, Caius G. Radu
Publikováno v:
Cell reports, vol 38, iss 2
Cell Rep
Cell Rep
We determine that type I interferon (IFN) response biomarkers are enriched in a subset of pancreatic ductal adenocarcinoma (PDAC) tumors; however, actionable vulnerabilities associated with IFN signaling have not been systematically defined. Integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184e71be22f63da9811bc2f5fbfa1b4e
https://escholarship.org/uc/item/62m2v7v7
https://escholarship.org/uc/item/62m2v7v7
Autor:
Kathleen Nguyen, Jeannine Gartmann, Ebrahim S. Delpassand, Ken Herrmann, Roger Slavik, Martin Allen-Auerbach, Rouzbeh Esfandiari, David Ranganathan, Jeremie Calais, Linda Gardner, Vincent Lok, Shadfar Bahri, Magnus Dahlbom, Pan Thin, Johannes Czernin, Andrei Gafita, Pawan Gupta, Wolfgang P. Fendler, Laura Gosa, Wesley R Armstrong, Tristan Grogan, Matthias Eiber, Andrew Quon
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 62, iss 10
J Nucl Med
J Nucl Med
The objective of this study was to determine prospectively the efficacy profile of 2 activity regimens of (177)Lu-PSMA therapy in patients with progressive metastatic castrate-resistant prostate cancer (mCRPC): 6.0 vs. 7.4 GBq. Methods: RESIST-PC (NC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354aa7aca16d8b533d44dfa8ed3839ad
https://pubmed.ncbi.nlm.nih.gov/34353872
https://pubmed.ncbi.nlm.nih.gov/34353872
Autor:
Timothy R. Donahue, Caius G. Radu, Thuc Le, Nanping Wu, Evan R. Abt, Khalid Rashid, Vincent Lok, Robert Damoiseaux, David W. Dawson, Woosuk Kim, Joseph R. Capri, Amanda M. Dann, Soumya Poddar, Luyi Li, Ethan W. Rosser, Ting-Ting Wu, Keke Liang, Johannes Czernin, Hailey R. Lee, Jing Cui, Amanda L. Creech
Publikováno v:
SSRN Electronic Journal.
An inflammatory, cytokine-rich tumor microenvironment is a defining feature of pancreatic ductal adenocarcinoma (PDAC). Among proinflammatory cytokines, type I interferons (IFNs) are particularly important as they regulate the expression of hundreds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb9dccfb604029a4768a62ec532ec451
https://doi.org/10.2139/ssrn.3883640
https://doi.org/10.2139/ssrn.3883640
Autor:
Aneta Turlik, Robert Damoiseaux, Joanna Li, Timothy R. Donahue, Daniel L. Sun, Selena Hernandez, Evan R. Abt, Wei Chen, Kendall N. Houk, Jeffrey I. Zink, Caius G. Radu, Andreea D. Stuparu, Karen Reue, Chi-An Cheng, Ethan W. Rosser, Johannes Czernin, Laurent Vergnes, Michael E. Jung, Christine E. Mona, Vincent Lok, Juno Van Valkenburgh, Xiaohong Chen, Roy D. Pan, Soumya Poddar, Thuc Le, Janet Song
Publikováno v:
RSC medicinal chemistry, vol 11, iss 3
A potent class of isoquinoline-based α-N-heterocyclic carboxaldehyde thiosemicarbazone (HCT) compounds has been rediscovered; based upon this scaffold, three series of antiproliferative agents were synthesized through iterative rounds of methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c2c5577be17a8d967044dcbbd0e9db
https://escholarship.org/uc/item/37j7d1kf
https://escholarship.org/uc/item/37j7d1kf
Autor:
Pan Thin, Kathleen Nguyen, Jeremie Calais, Jeannine Gartmann, Roger Slavik, Laura Gosa, Vincent Lok, Wolfgang P. Fendler, Ken Herrmann, Matthias Eiber, Johannes Czernin, Magnus Dahlbom, Wesley R Armstrong
Publikováno v:
Web of Science
5549 Background: This was an open-label randomized prospective bi-centric single-arm phase II clinical trial of 177Lu-PSMA-617 molecular radiotherapy in patients with progressive metastatic castrate-resistant prostate cancer (mCRPC) conducted at Univ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50500e09551cbe6cb8b0811f650caa4c
Autor:
Daniel L, Sun, Soumya, Poddar, Roy D, Pan, Ethan W, Rosser, Evan R, Abt, Juno, Van Valkenburgh, Thuc M, Le, Vincent, Lok, Selena P, Hernandez, Janet, Song, Joanna, Li, Aneta, Turlik, Xiaohong, Chen, Chi-An, Cheng, Wei, Chen, Christine E, Mona, Andreea D, Stuparu, Laurent, Vergnes, Karen, Reue, Robert, Damoiseaux, Jeffrey I, Zink, Johannes, Czernin, Timothy R, Donahue, Kendall N, Houk, Michael E, Jung, Caius G, Radu
Publikováno v:
RSC Med Chem
A potent class of isoquinoline-based α-N-heterocyclic carboxaldehyde thiosemicarbazone (HCT) compounds has been rediscovered; based upon this scaffold, three series of antiproliferative agents were synthesized through iterative rounds of methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b55a722fdd0d82b169a555313786e140
https://pubmed.ncbi.nlm.nih.gov/33479645
https://pubmed.ncbi.nlm.nih.gov/33479645