Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vincent Limburg"'
Autor:
Yevgen M Makogonenko, Dudley K. Strickland, Vincent Limburg, Natalya M. Ananyeva, Jose F. Ruiz, Diana V Kouiavskaia, Midori Shima, Alexey V. Khrenov, Evgueni L. Saenko, Alexander B. Meijer
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 19(2)
Coagulation factor VIII (FVIII) is a ligand for two members of the low-density lipoprotein receptor family, low-density lipoprotein receptor-related protein (LRP) and low-density lipoprotein receptor, which cooperate in regulating clearance of FVIII
Autor:
Koen Mertens, Carmen van der Zwaan, Sigrid D. Roosendaal, Kees W. Rodenburg, Alexander B. Meijer, Vincent Limburg
Publikováno v:
Blood. 110:1766-1766
The platelet α-granules contain a unique pool of partially activated factor V, which has been suggested to originate form megakaryocyte endocytosis of factor V (FV) from plasma. The presence of activated FV (FVa) in plasma itself should be tightly c
Autor:
Sigrid D. Roosendaal, Maartje van den Biggelaar, Alexander B. Meijer, Carmen van der Zwaan, Koen Mertens, Vincent Limburg, Kees W. Rodenburg, Bas de Laat
Publikováno v:
Blood. 110:1767-1767
Von Willebrand Factor (VWF) protects Factor VIII (FVIII) from rapid clearance of the cofactor from the circulations. This notion may agree with the observation that VWF blocks FVIII binding to LDL receptor (LDLR) and LDL receptor-related protein (LRP
Autor:
Koen Mertens, David Gestel, Alexander B. Meijer, Ed E. Moret, Vincent Limburg, Gunny van Stempvoort
Publikováno v:
Blood. 110:1762-1762
The formation of inhibitors against Factor VIII (FVIII) is one of the major adverse effects of FVIII substitution therapy in hemophilia A patients. Previously we have cloned a panel of antibodies from a phage display library from the VH gene repertoi