Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Vincent Laudone"'
1
Akademický článek
Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy
Autor: Charlotte S. Walmsley, Philip Jonsson, Michael L. Cheng, Sean McBride, Christopher Kaeser, Herbert Alberto Vargas, Vincent Laudone, Barry S. Taylor, Rajya Kappagantula, Priscilla Baez, Allison L. Richards, Anne Marie Noronha, Dilmi Perera, Michael Berger, David B. Solit, Christine A. Iacobuzio-Donahue, Howard I. Scher, Mark T. A. Donoghue, Wassim Abida, Alison M. Schram
Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract Reversion mutations that restore wild-type function of the BRCA gene have been described as a key mechanism of resistance to Poly(ADP-ribose) polymerase (PARP) inhibitor therapy in BRCA-associated cancers. Here, we report a case of a patient
Externí odkaz: https://doaj.org/article/13584368662940d8a5e228080b67724c
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2
Akademický článek
Can pelvic node dissection at radical prostatectomy influence the nodal recurrence at salvage lymphadenectomy for prostate cancer?
Autor: Arjun Sivaraman, Nicole Benfante, Karim Touijer, Jonathan Coleman, Peter Scardino, Vincent Laudone, James Eastham
Publikováno v: Investigative and Clinical Urology, Vol 59, Iss 2, Pp 83-90 (2018)
Purpose: To verify the quality of pelvic lymph node dissection (PLND) performed at radical prostatectomy (RP) and its impact on nodal recurrence in patients undergoing salvage lymph node dissection (sLND). Materials and Methods: Retrospective review
Externí odkaz: https://doaj.org/article/fe1ae1d999d44c15a36c768efe825a4b
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4
Oncologic Outcomes of Total Length Gleason Pattern 4 on Biopsy in Men with Grade Group 2 Prostate Cancer
Autor: Marlon Perera, Melissa J. Assel, Nicole E. Benfante, Andrew J. Vickers, Victor E. Reuter, Sigrid Carlsson, Vincent Laudone, Karim A. Touijer, James A. Eastham, Peter T. Scardino, Samson W. Fine, Behfar Ehdaie
Publikováno v: Journal of Urology. 208:309-316
Gleason Score 7 prostate cancer comprises a wide spectrum of disease risk, and precise substratification is paramount. Our group previously demonstrated that the total length of Gleason pattern (GP) 4 is a better predictor than %GP4 for adverse patho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8385af7c5e4c01c3434febeb610b800
https://doi.org/10.1097/ju.0000000000002685
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6
Outcomes of Grade Group 2 and 3 Prostate Cancer on Initial Versus Confirmatory Biopsy: Implications for Active Surveillance
Autor: Marlon Perera, Ghalib Jibara, Amy L. Tin, Samuel Haywood, Daniel D. Sjoberg, Nicole E. Benfante, Sigrid V. Carlsson, James A. Eastham, Vincent Laudone, Karim A. Touijer, Samson Fine, Peter T. Scardino, Andrew J. Vickers, Behfar Ehdaie
Publikováno v: European urology focus.
Active surveillance (AS) is recommended as the preferred treatment for men with low-risk disease. In order to optimize risk stratification and exclude undiagnosed higher-grade disease, most AS protocols recommend a confirmatory biopsy.We aimed to com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de771cea7920dec3083b70d005a5b91b
https://pubmed.ncbi.nlm.nih.gov/36566100
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