Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Vincent J Lynch"'
Autor:
Juan Manuel Vazquez, Maria T Pena, Baaqeyah Muhammad, Morgan Kraft, Linda B Adams, Vincent J Lynch
Publikováno v:
eLife, Vol 11 (2022)
The risk of developing cancer is correlated with body size and lifespan within species, but there is no correlation between cancer and either body size or lifespan between species indicating that large, long-lived species have evolved enhanced cancer
Externí odkaz:
https://doaj.org/article/69e8fb96cdcf4b1db8572ca517b8e041
Publikováno v:
eLife, Vol 11 (2022)
Structural and physiological changes in the female reproductive system underlie the origins of pregnancy in multiple vertebrate lineages. In mammals, the glandular portion of the lower reproductive tract has transformed into a structure specialized f
Externí odkaz:
https://doaj.org/article/24c619a007fb43eb8282130389f14fd9
Autor:
Katelyn Mika, Mirna Marinić, Manvendra Singh, Joanne Muter, Jan Joris Brosens, Vincent J Lynch
Publikováno v:
eLife, Vol 10 (2021)
Evolutionary changes in the anatomy and physiology of the female reproductive system underlie the origins and diversification of pregnancy in Eutherian (‘placental’) mammals. This developmental and evolutionary history constrains normal physiolog
Externí odkaz:
https://doaj.org/article/529e822206af440b934a83128cc84ff3
Publikováno v:
eLife, Vol 10 (2021)
The developmental origins and evolutionary histories of cell types, tissues, and organs contribute to the ways in which their dysfunction produces disease. In mammals, the nature, development and evolution of maternal-fetal interactions likely influe
Externí odkaz:
https://doaj.org/article/8ecdc894b64b46f4b8e8d4f70fd70ffa
Autor:
Juan M Vazquez, Vincent J Lynch
Publikováno v:
eLife, Vol 10 (2021)
The risk of developing cancer is correlated with body size and lifespan within species. Between species, however, there is no correlation between cancer and either body size or lifespan, indicating that large, long-lived species have evolved enhanced
Externí odkaz:
https://doaj.org/article/1856022384344fb6a3e8ee5bdf629083
Autor:
Mirna Marinić, Vincent J Lynch
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008666 (2020)
The steroid hormone progesterone, acting through the progesterone receptor (PR), a ligand-activated DNA-binding transcription factor, plays an essential role in regulating nearly every aspect of female reproductive biology. While many reproductive tr
Externí odkaz:
https://doaj.org/article/7a603bab60d641f6b0010f167168f29b
Autor:
Brandon L Pierce, Lin Tong, Samantha Dean, Maria Argos, Farzana Jasmine, Muhammad Rakibuz-Zaman, Golam Sarwar, Md Tariqul Islam, Hasan Shahriar, Tariqul Islam, Mahfuzar Rahman, Md Yunus, Vincent J Lynch, Devin Oglesbee, Joseph H Graziano, Muhammad G Kibriya, Mary V Gamble, Habibul Ahsan
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008172 (2019)
[This corrects the article DOI: 10.1371/journal.pgen.1007984.].
Externí odkaz:
https://doaj.org/article/542641df82d540e5b0e79529705bc06f
Autor:
Brandon L Pierce, Lin Tong, Samantha Dean, Maria Argos, Farzana Jasmine, Muhammad Rakibuz-Zaman, Golam Sarwar, Md Tariqul Islam, Hasan Shahriar, Tariqul Islam, Mahfuzar Rahman, Md Yunus, Vincent J Lynch, Devin Oglesbee, Joseph H Graziano, Muhammad G Kibriya, Mary V Gamble, Habibul Ahsan
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1007984 (2019)
Inorganic arsenic (iAs) is a carcinogen, and exposure to iAs via food and water is a global public health problem. iAs-contaminated drinking water alone affects >100 million people worldwide, including ~50 million in Bangladesh. Once absorbed into th
Externí odkaz:
https://doaj.org/article/1aba6777696e4dfa8e8bc0e75e54c65b
Autor:
Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P Mongan, Richard D Emes, Vincent J Lynch
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/78925d7991e64e18989f99b44a11c0b2
Autor:
Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P Mongan, Richard D Emes, Vincent J Lynch
Publikováno v:
eLife, Vol 5 (2016)
A major constraint on the evolution of large body sizes in animals is an increased risk of developing cancer. There is no correlation, however, between body size and cancer risk. This lack of correlation is often referred to as 'Peto's Paradox'. Here
Externí odkaz:
https://doaj.org/article/0ea76f26690c479db6fedee436f63684