Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vincent I. Poon"'
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of au
Externí odkaz:
https://doaj.org/article/180367eaef8f46cc8279934c7f0ee30b
Publikováno v:
Journal of Cancer Research and Therapeutic Oncology. 1:1-5
Macroautophagy, (heretofore referred to as autophagy) is thought to play a pivotal role in tumorigenesis and tumor cell survival. Autophagy is a self-degradative cellular process that recycles intracellular components such as proteins and lipids, and
Autor:
Mary A. Elrick, Vincent I. Poon, Jillian M. Brandon, Luke R. K. Hughson, Ninan Abraham, Katelin N. Townsend, Izabelle Gadawski, Julian J. Lum, E. John Wherry, Sarah MacPherson, Katrin Schlie, Lindsay DeVorkin, Hélène C. F. Côté, Ashley Westerback, Noboru Mizushima
Publikováno v:
The Journal of Immunology. 194:4277-4286
The activation and expansion of effector CD8+ T cells are essential for controlling viral infections and tumor surveillance. During an immune response, T cells encounter extrinsic and intrinsic factors, including oxidative stress, nutrient availabili
Autor:
Luke R. K. Hughson, Katelin N. Townsend, Julian J. Lum, Vincent I. Poon, Katrin Schlie, Ashley Westerback
Publikováno v:
Immunological Reviews. 249:176-194
Tumors and the immune system are intertwined in a competition where tilting the fine balance between tumor-specific immunity and tolerance can ultimately decide the fate of the host. Defensive and suppressive immunological responses to cancer are exq
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
International Journal of Cell Biology
International Journal of Cell Biology
Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of au
Autor:
Katelin N, Townsend, Luke R K, Hughson, Katrin, Schlie, Vincent I, Poon, Ashley, Westerback, Julian J, Lum
Publikováno v:
Immunological reviews. 249(1)
Tumors and the immune system are intertwined in a competition where tilting the fine balance between tumor-specific immunity and tolerance can ultimately decide the fate of the host. Defensive and suppressive immunological responses to cancer are exq
Autor:
Sajida Piperdi, Richard Gorlick, Michael Roth, Douglas S. Hawkins, Jonathan Gill, Erin R. Rudzinski, Vincent I Poon, David S. Geller
Publikováno v:
Clinical Sarcoma Research
Background Osteosarcoma is the most common primary malignant bone tumor in children and young adults. Ganglioside GD2 has been previously found on the cell surface in various tumor types, including osteosarcomas. Findings In this study, forty-nine ad