Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vincent Huson"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The authors show that graded molecular heterogeneity in metabotropic pathways underlies a continuum of temporal responses in cerebellar unipolar brush cells (UBCs). This allows the UBC population to serve as a cell-autonomous basis for temporal integ
Externí odkaz:
https://doaj.org/article/98d53dab60cf463d91e36550272c31ee
Autor:
Vincent Huson, Marieke Meijer, Rien Dekker, Mirelle ter Veer, Marvin Ruiter, Jan RT van Weering, Matthijs Verhage, Lennart Niels Cornelisse
Publikováno v:
eLife, Vol 9 (2020)
Previously, we showed that modulation of the energy barrier for synaptic vesicle fusion boosts release rates supralinearly (Schotten, 2015). Here we show that mouse hippocampal synapses employ this principle to trigger Ca2+-dependent vesicle release
Externí odkaz:
https://doaj.org/article/00c855a8f9194770b87e86987fba98f4
Autor:
Javier Emperador-Melero, Vincent Huson, Jan van Weering, Christian Bollmann, Gabriele Fischer von Mollard, Ruud F. Toonen, Matthijs Verhage
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Vti1a and Vti1b are SNARE proteins implicated in regulated secretion. Here the authors show that Vti1a and Vti1b control protein sorting at the Golgi, and targeting to the axon, and thereby indirectly control regulated secretion at the synapse.
Externí odkaz:
https://doaj.org/article/3904ee17225a4880a65ce6a3485a5952
Autor:
Sebastiaan Schotten, Marieke Meijer, Alexander Matthias Walter, Vincent Huson, Lauren Mamer, Lawrence Kalogreades, Mirelle ter Veer, Marvin Ruiter, Nils Brose, Christian Rosenmund, Jakob Balslev Sørensen, Matthijs Verhage, Lennart Niels Cornelisse
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/c4625afee7d54f3eb43b16b8afdaef97
Autor:
Sebastiaan Schotten, Marieke Meijer, Alexander Matthias Walter, Vincent Huson, Lauren Mamer, Lawrence Kalogreades, Mirelle ter Veer, Marvin Ruiter, Nils Brose, Christian Rosenmund, Jakob Balslev Sørensen, Matthijs Verhage, Lennart Niels Cornelisse
Publikováno v:
eLife, Vol 4 (2015)
The energy required to fuse synaptic vesicles with the plasma membrane (‘activation energy’) is considered a major determinant in synaptic efficacy. From reaction rate theory, we predict that a class of modulations exists, which utilize linear mo
Externí odkaz:
https://doaj.org/article/bfd259079baa4b2296cf1ca3aaaca15f
Autor:
Vincent Huson, Wade G. Regehr
Publikováno v:
Curr Opin Neurobiol
Synaptotagmin 7 (Syt7) is a multifunctional calcium sensor expressed throughout the body. Its high calcium affinity makes it well suited to act in processes triggered by modest calcium increases within cells. In synaptic transmission, Syt7 has been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d21bdd5666f3992ebde74f9d75aa996
https://doi.org/10.1016/j.conb.2020.02.006
https://doi.org/10.1016/j.conb.2020.02.006
Autor:
Mirelle ter Veer, Matthijs Verhage, Jan R.T. van Weering, R.J. Dekker, Marieke Meijer, Marvin Ruiter, Vincent Huson, L.N. Cornelisse
Publikováno v:
eLife, 9:e55713, 1-56. eLife Sciences Publications Limited
eLife
eLife, Vol 9 (2020)
eLife, 9:e55713, 1-56. eLife Sciences Publications
Huson, V, Meijer, M, Dekker, R, Veer, M T, Ruiter, M, van Weering, J, Verhage, M & Cornelisse, L N 2020, ' Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of synaptotagmin-1 ', eLife, vol. 9, e55713, pp. 1-56 . https://doi.org/10.7554/ELIFE.55713
eLife
eLife, Vol 9 (2020)
eLife, 9:e55713, 1-56. eLife Sciences Publications
Huson, V, Meijer, M, Dekker, R, Veer, M T, Ruiter, M, van Weering, J, Verhage, M & Cornelisse, L N 2020, ' Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of synaptotagmin-1 ', eLife, vol. 9, e55713, pp. 1-56 . https://doi.org/10.7554/ELIFE.55713
Previously, we showed that modulation of the energy barrier for synaptic vesicle fusion boosts release rates supralinearly (Schotten, 2015). Here we show that mouse hippocampal synapses employ this principle to trigger Ca2+-dependent vesicle release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2932bdf3c44f7bc3ed8d449574693c
https://research.vumc.nl/en/publications/23e14b4e-6797-44c4-a9ba-d2583103faf1
https://research.vumc.nl/en/publications/23e14b4e-6797-44c4-a9ba-d2583103faf1
Publikováno v:
Scientific Reports, 9(1):11341. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Huson, V, van Boven, M A, Stuefer, A, Verhage, M & Cornelisse, L N 2019, ' Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner ', Scientific Reports, vol. 9, no. 1, pp. 11341 . https://doi.org/10.1038/s41598-019-47487-9
Scientific Reports, 9(1). Nature Publishing Group
Huson, V, van Boven, M A, Stuefer, A, Verhage, M & Cornelisse, L N 2019, ' Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner ', Scientific Reports, vol. 9, no. 1, 11341 . https://doi.org/10.1038/s41598-019-47487-9
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Huson, V, van Boven, M A, Stuefer, A, Verhage, M & Cornelisse, L N 2019, ' Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner ', Scientific Reports, vol. 9, no. 1, pp. 11341 . https://doi.org/10.1038/s41598-019-47487-9
Scientific Reports, 9(1). Nature Publishing Group
Huson, V, van Boven, M A, Stuefer, A, Verhage, M & Cornelisse, L N 2019, ' Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner ', Scientific Reports, vol. 9, no. 1, 11341 . https://doi.org/10.1038/s41598-019-47487-9
Scientific Reports
To support frequency-coded information transfer, mammalian synapses tightly synchronize neurotransmitter release to action potentials (APs). However, release desynchronizes during AP trains, especially at room temperature. Here we show that suppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc8c7ab951482c36011a21af3d25865
https://research.vu.nl/en/publications/4f24e275-993d-4e32-93a6-2ca8066193bc
https://research.vu.nl/en/publications/4f24e275-993d-4e32-93a6-2ca8066193bc
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
To support frequency-coded information transfer, mammalian synapses tightly synchronize neurotransmitter release to action potentials (APs). However, release desynchronizes during AP trains, especially at room temperature. Here we show that suppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49cdb4cb5cb3ad4afc06661f400d3754
https://doi.org/10.1038/s41598-019-54233-8
https://doi.org/10.1038/s41598-019-54233-8
Autor:
Sebastiaan Schotten, Marieke Meijer, Alexander Matthias Walter, Vincent Huson, Lauren Mamer, Lawrence Kalogreades, Mirelle ter Veer, Marvin Ruiter, Nils Brose, Christian Rosenmund, Jakob Balslev Sørensen, Matthijs Verhage, Lennart Niels Cornelisse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d89d2e48ea5a6b1e02c61f5501fc61c
https://doi.org/10.7554/elife.05531.033
https://doi.org/10.7554/elife.05531.033