Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Vincent H.J. Van Der Velden"'
IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia
Autor:
Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
IKZF1-deletions occur in 10-15% of patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) and predict a poor outcome. However, the impact of IKZF1-loss on sensitivity to drugs used in contemporary treatment protocols has remained under
Externí odkaz:
https://doaj.org/article/70f5749bff5943bb9814e9df3159f0f2
Autor:
Inge van Outersterp, Vincent H.J. van der Velden, Patricia G. Hoogeveen, Goda E. Vaitkevičienė, Edwin Sonneveld, Gijs van Haaften, Roland P. Kuiper, Udo zur Stadt, Gabriele Escherich, Judith M. Boer, Monique L. den Boer
Publikováno v:
HemaSphere, Vol 7, Iss 10, p e967 (2023)
Externí odkaz:
https://doaj.org/article/ef1fe8fac5a545b3a961b76a6c0583e7
Autor:
Meral Beksac, Tulin Tuglular, Francesca Gay, Roberto Mina, Eirini Katodritou, Ali Unal, Michele Cavo, Guner Hayri Ozsan, Vincent H.J. van der Velden, Berna Beverloo, Michael Vermeulen, Mark van Duin, Guldane Cengiz, Omur Gokmen Sevindik, Serena Merante, Kyriaki Manousou, Pieter Sonneveld, Evangelos Terpos
Publikováno v:
HemaSphere, Vol 7, p e994593a (2023)
Externí odkaz:
https://doaj.org/article/a44f78ab5cda47d5a5a3846c78a3309a
Autor:
Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r). This can result in diagnostic confusion with Burkitt lymphoma/leukemia and use of individualized tr
Externí odkaz:
https://doaj.org/article/7ac03037b4cc476bb5a3d391aea80fe8
Autor:
Peter Bader, Emilia Salzmann-Manrique, Adriana Balduzzi, Jean-Hugues Dalle, Ann E. Woolfrey, Merav Bar, Michael R. Verneris, Michael J. Borowitz, Nirali N. Shah, Nathan Gossai, Peter J. Shaw, Allen R. Chen, Kirk R. Schultz, Hermann Kreyenberg, Lucia Di Maio, Gianni Cazzaniga, Cornelia Eckert, Vincent H.J. van der Velden, Rosemary Sutton, Arjan Lankester, Christina Peters, Thomas E. Klingebiel, Andre M. Willasch, Stephan A. Grupp, Michael A. Pulsipher
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3393-3405 (2019)
Abstract: Detection of minimal residual disease (MRD) pre– and post–hematopoietic cell transplantation (HCT) for pediatric acute lymphoblastic leukemia (ALL) has been associated with relapse and poor survival. Published studies have had insuffici
Externí odkaz:
https://doaj.org/article/53bb75b719364b6dba97e0eeac5290e5
Autor:
Stefan J. Erkeland, Christiaan J. Stavast, Joyce Schilperoord-Vermeulen, Giada Dal Collo, Harmen J.G. van de Werken, Leticia G. Leon, Antoinette van Hoven-Beijen, Iris van Zuijen, Yvonne M. Mueller, Eric M. Bindels, Dick de Ridder, Mies C. Kappers-Klunne, Kirsten van Lom, Vincent H.J. van der Velden, Anton W. Langerak
Publikováno v:
Haematologica, Vol 107, Iss 1 (2021)
T-cell prolymphocytic leukemia (T-PLL) is mostly characterized by aberrant expansion of small- to medium-sized prolymphocytes with a mature post-thymic phenotype, high aggressiveness of the disease and poor prognosis. However, T-PLL is more heterogen
Externí odkaz:
https://doaj.org/article/c51dcad216b44704bc99e3de44c2cf7a
Autor:
Davine Hofste op Bruinink, Stefania Oliva, Lucie Rihova, Alexander Schmitz, Milena Gilestro, Jeroen te Marvelde, Romana Kralova, Helle Høholt, Annemiek Broijl, Hans Erik Johnsen, Roman Hajek, Mario Boccadoro, Pieter Sonneveld, Paola Omedè, Vincent H.J. van der Velden
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/2e62a93c1e5a446097540e148434f786
Autor:
Marius Flasinski, Kira Scheibke, Martin Zimmermann, Ursula Creutzig, Katarina Reinhardt, Femke Verwer, Valerie de Haas, Vincent H.J. van der Velden, Christine von Neuhoff, C. Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusmann
Publikováno v:
Blood Advances, Vol 2, Iss 13, Pp 1532-1540 (2018)
Abstract: Approximately 5% to 10% of children with Down syndrome (DS) are diagnosed with transient myeloproliferative disorder (TMD). Approximately 20% of these patients die within 6 months (early death), and another 20% to 30% progress to myeloid le
Externí odkaz:
https://doaj.org/article/51672d643559410a9f68e6fc94eba776
Autor:
Prisca M.J. Theunissen, David van Zessen, Andrew P. Stubbs, Malek Faham, Christian M. Zwaan, Jacques J.M. van Dongen, Vincent H.J. Van Der Velden
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
In B-cell precursor acute lymphoblastic leukemia, the initial leukemic cells share the same antigen receptor gene rearrangements. However, due to ongoing rearrangement processes, leukemic cells with different gene rearrangement patterns can develop,
Externí odkaz:
https://doaj.org/article/e34f4e8107b84824a566853750a2331f
Autor:
Eline M.P. Cremers, Theresia M. Westers, Canan Alhan, Claudia Cali, Heleen A. Visser-Wisselaar, Dana A. Chitu, Vincent H.J. van der Velden, Jeroen G. te Marvelde, Saskia K. Klein, Petra Muus, Edo Vellenga, Georgina E. de Greef, Marie-Cecile C.J.C. Legdeur, Pierre W. Wijermans, Marian J.P.L. Stevens-Kroef, Pedro da Silva-Coelho, Joop H. Jansen, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
Flow cytometric analysis is a recommended tool in the diagnosis of myelodysplastic syndromes. Current flow cytometric approaches evaluate the (im)mature myelo-/monocytic lineage with a median sensitivity and specificity of ~71% and ~93%, respectively
Externí odkaz:
https://doaj.org/article/ce60285c497d4c0a8b8092e8a4f0c35f