Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Vincent Guacci"'
Publikováno v:
eLife, Vol 8 (2019)
Cohesin mediates higher order chromosome structure. Its biological activities require topological entrapment of DNA within a lumen(s) formed by cohesin subunits. The reversible dissociation of cohesin’s Smc3p and Mcd1p subunits is postulated to for
Externí odkaz:
https://doaj.org/article/b71522bc10d74f0387a7f4e1e58db4b7
Publikováno v:
eLife, Vol 4 (2015)
Cohesin tethers together regions of DNA, thereby mediating higher order chromatin organization that is critical for sister chromatid cohesion, DNA repair and transcriptional regulation. Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPa
Externí odkaz:
https://doaj.org/article/59bbd422b8d44826b0be02a3db32a3d9
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005036 (2015)
The Structural Maintenance of Chromosome (SMC) complex, termed cohesin, is essential for sister chromatid cohesion. Cohesin is also important for chromosome condensation, DNA repair, and gene expression. Cohesin is comprised of Scc3, Mcd1, Smc1, and
Externí odkaz:
https://doaj.org/article/a63c9771bf9b43a48bfaae1dea76198b
Autor:
Laura A Díaz-Martínez, Juan F Giménez-Abián, Yoshiaki Azuma, Vincent Guacci, Gonzalo Giménez-Martín, Lorene M Lanier, Duncan J Clarke
Publikováno v:
PLoS ONE, Vol 1, p e53 (2006)
BACKGROUND:The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are remove
Externí odkaz:
https://doaj.org/article/2bb829e6407144e9aa551e5bb6d27c83
Autor:
Kevin Boardman, Siheng Xiang, Fiona Chatterjee, Udochi Mbonu, Vincent Guacci, Douglas Koshland
Publikováno v:
Genes & development, vol 37, iss 7-8
The evolutionarily conserved cohesin complex mediates sister chromatid cohesion and facilitates mitotic chromosome condensation, DNA repair, and transcription regulation. These biological functions require cohesin's two ATPases, formed by the Smc1p a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84118f092c042a3e005922e14a3331c
https://escholarship.org/uc/item/1zr7b7nn
https://escholarship.org/uc/item/1zr7b7nn
Autor:
Kevin M. Boardman, Siheng Xiang, Fiona Chatterjee, Udochi Mbonu, Vincent Guacci, Douglas Koshland
The evolutionarily conserved cohesin complex mediates sister chromatid cohesion and facilitates mitotic chromosome condensation, DNA repair, and transcription regulation. These biological functions require cohesin’s two ATPases, formed by the Smc1p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0438d0d659e63c29ef64d080cd3625f0
https://doi.org/10.1101/2022.11.23.517716
https://doi.org/10.1101/2022.11.23.517716
Publikováno v:
Genetics
Cohesin tethers DNA to mediate sister chromatid cohesion, chromosome condensation, and DNA repair. How the cell regulates cohesin to perform these distinct functions remains to be elucidated. One cohesin regulator, Wpl1p, was characterized in Sacchar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6132e52b1c6af9888efc1ecaaa3c71e8
https://doi.org/10.1534/genetics.117.300537
https://doi.org/10.1534/genetics.117.300537
Autor:
Michelle S. Bloom, Douglas Koshland, Vincent Guacci, Jeremiah Stricklin, Xuánzōng Guō, Meghna Bhatter
Publikováno v:
Molecular Biology of the Cell
American Society for Cell Biology
American Society for Cell Biology
Cohesin complex mediates cohesion between sister chromatids, which promotes high-fidelity chromosome segregation. Eco1p acetylates the cohesin subunit Smc3p during S phase to establish cohesion. The current model posits that this Eco1p-mediated acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9071a693b73c73f34df0b6d53f11fd1a
http://europepmc.org/articles/PMC4279223
http://europepmc.org/articles/PMC4279223
Publikováno v:
Molecular Biology of the Cell
A single cohesin is believed to be sufficient to tether sister chromatids. Three examples of interallelic complementation are identified and characterized in which two different mutant cohesin complexes interact to promote cohesin functions. The resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5a5d545ac65bcc9351fc3aaaa6ea92
http://europepmc.org/articles/PMC4642856
http://europepmc.org/articles/PMC4642856