Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vincent Groenewold"'
Autor:
Veerle Fleskens, Carlos M. Minutti, Xingmei Wu, Ping Wei, Cornelieke E.G.M. Pals, James McCrae, Saskia Hemmers, Vincent Groenewold, Harm-Jan Vos, Alexander Rudensky, Fan Pan, Huabin Li, Dietmar M. Zaiss, Paul J. Coffer
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3600-3612.e6 (2019)
Summary: The Foxp3 transcription factor is a crucial determinant of both regulatory T (TREG) cell development and their functional maintenance. Appropriate modulation of tolerogenic immune responses therefore requires the tight regulation of Foxp3 tr
Externí odkaz:
https://doaj.org/article/8afbd001b6f74f43bf11390f6c3c68e8
Autor:
Harmjan R. Vos, D Versteeg, Mauro Giacca, Vincent Groenewold, M. Huibers, E. van Rooij, Danny Huylebroeck, Monika M Gladka, Lieneke Kooijman, Arwa Kohela, Bas Molenaar
Publikováno v:
Journal of Molecular and Cellular Cardiology. 120:17-18
Autor:
Mathijs Vleugel, Manja Omerzu, Vincent Groenewold, Geert J. P. L. Kops, Wilco Nijenhuis, Berend Snel, Eelco C. Tromer
Publikováno v:
The Journal of Cell Biology
The kinetochore scaffold KNL1 contains an extensive array of short linear sequence modules that each independently can localize BUB1 but that together provide enhanced efficiency of chromosome segregation.
Fidelity of chromosome segregation reli
Fidelity of chromosome segregation reli
Autor:
Geert J. P. L. Kops, Tale Sliedrecht, Tim A. Hoek, Manja Omerzu, Eelco C. Tromer, Vincent Groenewold, Mathijs Vleugel
Publikováno v:
Journal of Cell Science.
Mitotic chromosome segregation is initiated by the anaphase promoting complex/cyclosome (APC/C) and its co-activator CDC20 (forming APC/CCDC20). APC/CCDC20 is inhibited by the spindle assembly checkpoint (SAC) when chromosomes have not attached to sp
Autor:
Mathijs Vleugel, Susanne M.A. Lens, Vincent Groenewold, Manja Omerzu, Geert J. P. L. Kops, Michael A. Hadders
Publikováno v:
Molecular Cell, 57(5), 824. Cell Press
Regulated recruitment of the kinase-adaptor complex BUB1/BUB3 to kinetochores is crucial for correcting faulty chromosome-spindle attachments and for spindle assembly checkpoint (SAC) signaling. BUB1/BUB3 localizes to kinetochores by binding phosphor
Publikováno v:
van Raam, B J, Drewniak, A, Groenewold, V, van den Berg, T K & Kuijpers, T W 2008, ' Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3 ', Blood, vol. 112, no. 5, pp. 2046-54 . https://doi.org/10.1182/blood-2008-04-149575
Blood, 112(5), 2046-54. American Society of Hematology
Blood, 112(5), 2046-2054. American Society of Hematology
Blood, 112(5), 2046-54. American Society of Hematology
Blood, 112(5), 2046-2054. American Society of Hematology
Neutrophils have a very short life span and undergo apoptosis within 24 hours after leaving the bone marrow. Granulocyte colony-stimulating factor (G-CSF) is essential for the recruitment of fresh neutrophils from the bone marrow but also delays apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5784705f0fdfd52d6a4dac5de3fb946
https://research.vumc.nl/en/publications/e15cfd55-eb98-4d8c-9f54-2a4191a0cb7f
https://research.vumc.nl/en/publications/e15cfd55-eb98-4d8c-9f54-2a4191a0cb7f
Autor:
José María Carazo, Judith Klumperman, Carlos Sacristan, Misbha Ud Din Ahmad, Roberto Melero, Eelco C. Tromer, Job Fermie, Geert J. P. L. Kops, Anastassis Perrakis, Andrea Musacchio, Vincent Groenewold, Alexander Fish, Jenny Keller
Publikováno v:
Nature cell biology
Nature Cell Biology
Nature Cell Biology, 20(7), 800. Nature Publishing Group
Nature Cell Biology, 20(7), 800-810. Nature Publishing Group
Nature Cell Biology
Nature Cell Biology, 20(7), 800. Nature Publishing Group
Nature Cell Biology, 20(7), 800-810. Nature Publishing Group
Faithful chromosome segregation depends on the ability of sister kinetochores to attach to spindle microtubules. An outer layer of the kinetochore known as the fibrous corona transiently expands in early mitosis and disassembles upon microtubule capt