Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Vincent F. Castellucci"'
Publikováno v:
Journal of Neurochemistry. 97:79-91
To investigate the mechanisms underlying regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation in Aplysia neurons, we have cloned the Aplysia homolog of the vertebrate eIF4E kinases, Mnk1 and -2. Aplysia Mnk shares many conserved regi
Autor:
Demian Barbas, Habib A. Mohamed, Stephane Angers, Michel Bouvier, Luc DesGroseillers, Vincent F. Castellucci, Jacques P. Zappulla, John H. Byrne
Publikováno v:
Journal of Neurochemistry. 96:414-427
In Aplysia, the neurotransmitter dopamine is involved in the regulation of various physiological processes and motor functions, like feeding behaviour, and in the siphon-gill withdrawal reflex. In this paper, we report the characterization of the fir
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 140:403-409
The actin family encodes a large number of protein isoforms with quasi-identical primary structure but distinct function and localization. In oocytes, actin is known to play important roles in different processes such as those leading to fertilizatio
Publikováno v:
The Journal of Comparative Neurology. 490:295-304
Aplysia californica is a powerful model for understanding the cellular and molecular mechanisms underlying modulation of neuronal plasticity and learning. In the central nervous system of Aplysia, serotonin is associated with various behaviors. For e
Publikováno v:
Journal of Neurochemistry. 89:354-363
We have identified an alternatively spliced form of synaptotagmin I in Aplysia neurons. This isoform, synaptotagmin I C2B-b, is generated by alternative exon usage in the C2B domain leading to nine amino acid changes in the C2B sequence from the prev
Publikováno v:
Neuroscience. 116:13-17
Activation of the extracellular signal-related kinase is important for long-term increases in synaptic strength in the Aplysia nervous system. However, there is little known about the mechanism for the activation of the kinase in this system. We exam
Publikováno v:
Journal of Neurochemistry. 66:2596-2605
Peptidylglycine alpha-amidating enzyme (PAM; EC 1.14.17.3) is responsible for the conversion of peptides with a COOH-terminal glycine into alpha-amidated peptides, a posttranslational modification often required for biological activity and/or increas
Autor:
Vincent F. Castellucci, Tanja Ouimet
Publikováno v:
Journal of Neurochemistry. 68:1031-1040
Peptide diversity can be regulated in many ways. One of the possible mechanisms of such a regulation may lie in the differential processing of a precursor in a tissue-specific manner or in a modulated processing within a single cell. To address these
Autor:
Frédéric Manseau, Jonathan Hislop, Wayne S. Sossin, Stephanie K. Yanow, Vincent F. Castellucci
Publikováno v:
Journal of Neurochemistry. 70:572-583
In the marine mollusk Aplysia californica, serotonin initiates three phases of translational regulation: an initial decrease in translation, followed by a transient increase in protein synthesis, both of which are independent of transcription, follow
Publikováno v:
The Journal of Neuroscience. 21:1247-1256
At nondepressedAplysiasensory to motor synapses, serotonin (5-HT) facilitates transmitter release primarily through a protein kinase A pathway. In contrast, at depressedAplysiasensory to motor synapses, 5-HT facilitates transmitter release primarily