Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Vincent Diemer"'
Autor:
Vincent Diemer, Nathalie Ollivier, Bérénice Leclercq, Hervé Drobecq, Jérôme Vicogne, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Control of cysteine reactivity is of paramount importance for the synthesis of proteins using native chemical ligation. Here, the authors report a readily cleavable N-selenoethyl group attached to cysteine and apply it to the modular assembly of line
Externí odkaz:
https://doaj.org/article/024061c5d12c406ea5bee1e0d5dcde35
Publikováno v:
Organic Letters. 25:2696-2700
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, 2022, 87 (14), pp.9426-9430. ⟨10.1021/acs.joc.2c00934⟩
Journal of Organic Chemistry, 2022, 87 (14), pp.9426-9430. ⟨10.1021/acs.joc.2c00934⟩
International audience; The arylthiol 4-mercaptophenylacetic acid (MPAA) is a powerful catalyst of selenosulfide bond reduction by the triarylphosphine 3,3′,3″-phosphanetriyltris(benzenesulfonic acid) trisodium salt (TPPTS). Both reagents are wat
Publikováno v:
Total Chemical Synthesis of Proteins
Frontispiece: Pedal to the Metal: The Homogeneous Catalysis of the Native Chemical Ligation Reaction
Publikováno v:
Chemistry – A European Journal. 28
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, 2022, 28 (16), ⟨10.1002/chem.202104229⟩
Chemistry-A European Journal, 2022, 28 (16), ⟨10.1002/chem.202104229⟩
International audience; The native chemical ligation reaction of peptide thioesters with cysteinyl peptides is a pivotal chemical process in the production of native or modified peptides and proteins, and well beyond in the preparation of various bio
Publikováno v:
Accounts of Chemical Research
Accounts of Chemical Research, 2022, 55 (18), pp.2685-2697. ⟨10.1021/acs.accounts.2c00436⟩
Accounts of Chemical Research, 2022, 55 (18), pp.2685-2697. ⟨10.1021/acs.accounts.2c00436⟩
International audience; The last two decades have witnessed the rise in power of chemical protein synthesis to the point where it now constitutes an established corpus of synthetic methods efficiently complementing biological approaches. One factor e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25d30988c109eac50a1019761e52490
https://hal.science/hal-03780544
https://hal.science/hal-03780544
Autor:
Vincent Diemer, Oleg Melnyk
Publikováno v:
Chem
Chem, 2022, 8 (10), pp.2571-2573. ⟨10.1016/j.chempr.2022.09.011⟩
Chem, 2022, 8 (10), pp.2571-2573. ⟨10.1016/j.chempr.2022.09.011⟩
International audience; Today, the development of powerful one-pot techniques combining native chemical ligation and cysteine reductive desulfurization is central to the production of proteins by chemical synthesis. In the September issue of Chem, Xu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c205cf4b0e8a27a90713437cb5aca92e
https://doi.org/10.1016/j.chempr.2022.09.011
https://doi.org/10.1016/j.chempr.2022.09.011
Publikováno v:
Chemical Protein Synthesis
Xuechen Li. Chemical Protein Synthesis, 2530, Springer US, pp.213-239, 2022, Methods in Molecular Biology, 978-1-0716-2488-3. ⟨10.1007/978-1-0716-2489-0_15⟩
Methods in Molecular Biology ISBN: 9781071624883
Xuechen Li. Chemical Protein Synthesis, 2530, Springer US, pp.213-239, 2022, Methods in Molecular Biology, 978-1-0716-2488-3. ⟨10.1007/978-1-0716-2489-0_15⟩
Methods in Molecular Biology ISBN: 9781071624883
International audience; N-selenoethyl cysteine (SetCys) in the form of its cyclic selenosulfide is a cysteine surrogate, whose reactivity depends on the reducing power of the medium. SetCys does not interfere with the native chemical ligation reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14176550ef4b8bccca84658eafafca04
https://hal.science/hal-03833960
https://hal.science/hal-03833960
Publikováno v:
Current Opinion in Chemical Biology
Current Opinion in Chemical Biology, Elsevier, 2020, 58, pp.1-9. ⟨10.1016/j.cbpa.2020.02.007⟩
Current Opinion in Chemical Biology, 2020, 58, pp.1-9. ⟨10.1016/j.cbpa.2020.02.007⟩
Current Opinion in Chemical Biology, Elsevier, 2020, 58, pp.1-9. ⟨10.1016/j.cbpa.2020.02.007⟩
Current Opinion in Chemical Biology, 2020, 58, pp.1-9. ⟨10.1016/j.cbpa.2020.02.007⟩
The review gives a large overview of the strategies used for protein synthesis by chemoselective peptide segment ligation on a solid support. It discusses also important aspects that remain to be explored to further develop the technology such as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5ef88ab280c1278fe1a437ff28e68c
https://hal.archives-ouvertes.fr/hal-02734384
https://hal.archives-ouvertes.fr/hal-02734384