Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vincent Damian"'
Autor:
Jennifer D. Deem, David Tingley, Christina A. Watts, Kayoko Ogimoto, Caeley L. Bryan, Bao Anh N. Phan, Vincent Damian, Michael R. Bruchas, Jarrad M. Scarlett, Michael W. Schwartz, Gregory J. Morton
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101835- (2023)
Objective: Preserving core body temperature across a wide range of ambient temperatures requires adaptive changes of thermogenesis that must be offset by corresponding changes of energy intake if body fat stores are also to be preserved. Among neuron
Externí odkaz:
https://doaj.org/article/7556e099c97e49cabbcd44cff2dcf9cc
Autor:
Jennifer D Deem, Chelsea L Faber, Christian Pedersen, Bao Anh Phan, Sarah A Larsen, Kayoko Ogimoto, Jarrell T Nelson, Vincent Damian, Megan A Tran, Richard D Palmiter, Karl J Kaiyala, Jarrad M Scarlett, Michael R Bruchas, Michael W Schwartz, Gregory J Morton
Publikováno v:
eLife, Vol 9 (2020)
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Externí odkaz:
https://doaj.org/article/3bf1e03edc9c473196f7e1c90cbf2a36
Autor:
Mauricio D. Dorfman, Jordan E. Krull, John D. Douglass, Rachael Fasnacht, Fernando Lara-Lince, Thomas H. Meek, Xiaogang Shi, Vincent Damian, Hong T. Nguyen, Miles E. Matsen, Gregory J. Morton, Joshua P. Thaler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Unlike males, female mice are resistant to hypothalamic inflammation and weight gain when fed a high-fat diet. Here, the authors reveal sex-specific regulation of hypothalamic microglial activation through CX3CR1 signalling, providing a potential mec
Externí odkaz:
https://doaj.org/article/c3d9bcc58c004e1b9f6eb255e257f3c4
Autor:
Karl J. Kaiyala, Jarrad M. Scarlett, Michael W. Schwartz, Chelsea L. Faber, Vincent Damian, Gregory J. Morton, Sarah A Larsen, Megan A. Tran, Christian E. Pedersen, Bao Anh Phan, Richard D. Palmiter, Kayoko Ogimoto, Jennifer D. Deem, Jarrell T. Nelson, Michael R. Bruchas
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Autor:
Jennifer D. Deem, Bao Anh N. Phan, Michael R. Bruchas, Sarah A Larsen, Megan A. Tran, Vincent Damian, Christian E. Pedersen, Chelsea L. Faber, Kayoko Ogimoto, Michael W. Schwartz, Karl J. Kaiyala, Jarrad M. Scarlett, Gregory J. Morton
Publikováno v:
Diabetes. 69
Although hyperphagic feeding during cold exposure is widely viewed as a response to the negative energy state that results from increased thermogenesis, the underlying mechanisms are unknown. We investigated an alternative hypothesis, that during col
Autor:
Gregory J. Morton, Bao Anh Phan, Chelsea L. Faber, Vincent Damian, Kevin R. Velasco, Miles E. Matsen, Michael W. Schwartz, Anthony Therattil, Daniel Adam
Publikováno v:
Diabetes
The hypothalamic ventromedial nucleus (VMN) is implicated both in autonomic control of blood glucose and in behaviors including fear and aggression, but whether these divergent effects involve the same or distinct neuronal subsets and their projectio
Autor:
Chelsea L. Faber, Vincent Damian, Jonathan N. Flak, Colby L. Samstag, Thomas H. Meek, Gregory J. Morton, Hong T. Nguyen, Jarrad M. Scarlett, Miles E. Matsen, Martin G. Myers
Publikováno v:
Endocrinology. 159:1585-1594
Growing evidence implicates neurons that project from the lateral parabrachial nucleus (LPBN) to the hypothalamic ventromedial nucleus (VMN) in a neurocircuit that drives counterregulatory responses to hypoglycemia, including increased glucagon secre
Autor:
Chelsea L. Faber, Vincent Damian, Michael W. Schwartz, Gregory J. Morton, Trista J. Harvey, Kevin R. Velasco
Publikováno v:
Diabetes. 68
A role for leptin receptor (LepR)-expressing neurons in the hypothalamic ventromedial nucleus (VMN) in glucose homeostasis is suggested by studies in which leptin is administered into, or leptin receptors are deleted from, this brain area. However, w
Autor:
JENNIFER D. DEEM, KAYOKO OGIMOTO, JARRELL NELSON, BAO ANH N. PHAN, KEVIN R. VELASCO, VINCENT DAMIAN, ZACHARY KNIGHT, MICHAEL W. SCHWARTZ, GREGORY J. MORTON
Publikováno v:
Diabetes. 68
Inhibition of warm sensitive neurons (WSNs) in the hypothalamic preoptic area (POA) has been suggested to play a key role in the thermogenic response to cold exposure. As this response is enabled by a marked increase of insulin sensitivity in thermog
Autor:
Jarrell T. Nelson, Gregory J. Morton, Bao Anh N. Phan, Jennifer D. Deem, Vincent Damian, Michael W. Schwartz, Kevin R. Velasco, Kayoko Ogimoto
Publikováno v:
Diabetes. 68
The adaptive response to cold exposure includes matched increases of both energy expenditure (to support thermogenesis) and energy intake, enabling core temperature to be maintained with no change of body fat stores. To investigate whether activation