Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vincent Cannataro"'
Publikováno v:
Cancer research.
Somatic nucleotide mutations can contribute to cancer cell survival, proliferation, and pathogenesis. Although research has focused on identifying which mutations are “drivers” versus “passengers," quantifying the proliferative effects of speci
Publikováno v:
Molecular Biology and Evolution. 39
Mutational processes in tumors create distinctive patterns of mutations, composed of neutral “passenger” mutations and oncogenic drivers that have quantifiable effects on the proliferation and survival of cancer cell lineages. Increases in prolif
Abstract A055: Altered RNA splicing causes pancreatic cancer and exposes a therapeutic vulnerability
Autor:
Natasha Pinto Medici, Diana Martinez Saucedo, Danny Lee, Li-Ting Ku, Robert Tseng, Vincent Cannataro, Deanne Yugawa, Sumedha Chowdhury, Jeffrey Townsend, Christine A. Iacobuzio-Donahue, Omar Abdel-Wahab, Steven D. Leach, Luisa Escobar-Hoyos
Publikováno v:
Cancer Research. 82:A055-A055
With the aim to identify new second-hit mutations that cause pancreatic ductal adenocarcinoma (PDAC), other than mutations in p53, we performed a genetic interaction analysis based on the concept of mutually exclusive mutations, which suggests that m
Autor:
Elisabeth, Cox-Paulson, Vincent, Cannataro, Thomas, Gallagher, Corey, Hoffman, Gary, Mantione, Matthew, Mcintosh, Malan, Silva, Nicole, Vissichelli, Rachel, Walker, Jeffrey, Simske, Shoichiro, Ono, Harold, Hoops
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 243(6)
Tropomodulins are actin-capping proteins that regulate the stability of the slow-growing, minus-ends of actin filaments. The C. elegans tropomodulin homolog, UNC-94, has sequence and functional similarity to vertebrate tropomodulins. We investigated