2018-2019 human seasonal H3N2 influenza A virus spillovers into swine with demonstrated virus transmission in pigs were not sustained in the pig population.

Autor: Powell JD; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA., Thomas MN; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.; Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Anderson TK; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA., Zeller MA; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Gauger PC; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA., Vincent Baker AL; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.

Publikováno v: Journal of virology [J Virol] 2024 Nov 11, pp. e0008724. Date of Electronic Publication: 2024 Nov 11.

Potential pandemic risk of circulating swine H1N2 influenza viruses.

Autor: Le Sage V; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Rockey NC; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Civil and Environmental Engineering, Duke University, Durham, NC, USA., French AJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., McBride R; Departments of Molecular Medicine and Immunology & Microbiology, The Scripps Research Institute, La Jolla, CA, USA., McCarthy KR; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Rigatti LH; Division of Laboratory Animal Resources, University of Pittsburgh, Pittsburgh, PA, USA., Shephard MJ; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA., Jones JE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Walter SG; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Doyle JD; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Division of Infectious Diseases, Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Xu L; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Division of Infectious Diseases, Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Barbeau DJ; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Division of Infectious Diseases, Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Wang S; Departments of Molecular Medicine and Immunology & Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Frizzell SA; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Myerburg MM; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Paulson JC; Departments of Molecular Medicine and Immunology & Microbiology, The Scripps Research Institute, La Jolla, CA, USA., McElroy AK; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Division of Infectious Diseases, Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Anderson TK; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, IA, USA., Vincent Baker AL; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, IA, USA., Lakdawala SS; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. seema.s.lakdawala@emory.edu.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. seema.s.lakdawala@emory.edu.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. seema.s.lakdawala@emory.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 13; Vol. 15 (1), pp. 5025. Date of Electronic Publication: 2024 Jun 13.

Amino acid 138 in the HA of a H3N2 subtype influenza A virus increases affinity for the lower respiratory tract and alveolar macrophages in pigs.

Autor: Cardenas M; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Seibert B; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Cowan B; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Fraiha ALS; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Carnaccini S; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Gay LC; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Faccin FC; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Caceres CJ; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Anderson TK; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, United States of America., Vincent Baker AL; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, United States of America., Perez DR; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America., Rajao DS; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Feb 20; Vol. 20 (2), pp. e1012026. Date of Electronic Publication: 2024 Feb 20 (Print Publication: 2024).

Mucin 4 is a cellular biomarker of necrotizing bronchiolitis in influenza A virus infection.

Autor: Arruda BL; Virus and Prion Research Unit, National Animal Disease Center, USDA Agricultural Research Service, 1920 Dayton Ave, Ames, IA 50010, USA. Electronic address: bailey.arruda@usda.gov., Kanefsky RA; Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Rd, North Grafton, MA 01536, USA., Hau S; Virus and Prion Research Unit, National Animal Disease Center, USDA Agricultural Research Service, 1920 Dayton Ave, Ames, IA 50010, USA., Janzen GM; Virus and Prion Research Unit, National Animal Disease Center, USDA Agricultural Research Service, 1920 Dayton Ave, Ames, IA 50010, USA., Anderson TK; Virus and Prion Research Unit, National Animal Disease Center, USDA Agricultural Research Service, 1920 Dayton Ave, Ames, IA 50010, USA., Vincent Baker AL; Virus and Prion Research Unit, National Animal Disease Center, USDA Agricultural Research Service, 1920 Dayton Ave, Ames, IA 50010, USA.

Publikováno v: Microbes and infection [Microbes Infect] 2023 Sep-Oct; Vol. 25 (7), pp. 105169. Date of Electronic Publication: 2023 Jun 08.

Characterizing a century of genetic diversity and contemporary antigenic diversity of N1 neuraminidase in influenza A virus from North American swine.

Autor: Hufnagel DE; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, Ames, IA 50010, USA., Young KM; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, Ames, IA 50010, USA., Arendsee ZW; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, Ames, IA 50010, USA., Gay LC; Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Rd, Athens, GA 30602, USA., Caceres CJ; Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Rd, Athens, GA 30602, USA., Rajão DS; Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Rd, Athens, GA 30602, USA., Perez DR; Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Rd, Athens, GA 30602, USA., Vincent Baker AL; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, Ames, IA 50010, USA., Anderson TK; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, Ames, IA 50010, USA.

Publikováno v: Virus evolution [Virus Evol] 2023 Feb 28; Vol. 9 (1), pp. vead015. Date of Electronic Publication: 2023 Feb 28 (Print Publication: 2023).