Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Vincent L. Chen"'
Autor:
Kelly C. Cushing-Damm, Yanhua Chen, Xiaomeng Du, Annapurna Kuppa, Chinmay Raut, Antonino Oliveri, Vincent L. Chen, Brett Vanderwerff, Matt Zawistowski, Krishna Rao, Peter Higgins, Elizabeth K. Speliotes
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT Patients with inflammatory bowel disease (IBD) are at increased risk of Clostridioides difficile infection (CDI). Herein, we aimed to determine if genetic risk contributes to this observed association. We carried out a genome-wide associatio
Externí odkaz:
https://doaj.org/article/3d89802674fd4c69978ce1aa0affac71
Autor:
Pojsakorn Danpanichkul, Kanokphong Suparan, Cheng Han Ng, Disatorn Dejvajara, Siwanart Kongarin, Nuttada Panpradist, Nathorn Chaiyakunapruk, Mark D. Muthiah, Vincent L. Chen, Daniel Q. Huang, Luis Antonio Díaz, Mazen Noureddin, Juan Pablo Arab, Karn Wijarnpreecha
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101020- (2024)
Background & Aims: Alcohol-associated liver diseases (ALDs) and alcohol use disorder (AUD) pose a global health risk. AUD is underrecognized in the elderly, and the burden of AUD complications, including ALD, may increase with aging populations and r
Externí odkaz:
https://doaj.org/article/97a54cabddf046098365d75831930d0c
Autor:
Andrew M. Brown, Ihab Kassab, Marco Massani, Whitney Townsend, Amit G. Singal, Cigdem Soydal, Laura Moreno‐Luna, Lewis R. Roberts, Vincent L. Chen, Neehar D. Parikh
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 2590-2599 (2023)
Abstract Background Transarterial radioembolization (TARE) is increasingly used as an alternative to transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma (HCC). We aimed to perform an overall and individual patient dat
Externí odkaz:
https://doaj.org/article/996b10ec82214758b7dabbcbc6068aa2
Autor:
Vincent L. Chen, Qianhui Huang, Ramdane Harouaka, Yuheng Du, Anna S. Lok, Neehar D. Parikh, Lana X. Garmire, Max S. Wicha
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1482-1491 (2022)
Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide. Identification and sequencing of circulating tumor (CT) cells and clusters may allow for noninvasive molecular characterization of HCC, which is an unmet need, as many patie
Externí odkaz:
https://doaj.org/article/ec1169c729cb4aed9defa3d7cc42afb6
Publikováno v:
Hepatology Communications, Vol 7, Iss 3, Pp e0044-e0044 (2023)
Objectives:. Weight loss is the mainstay of treatment of NAFLD, but longitudinal data on weight changes and their impact on liver disease are limited. We aimed to characterize weight trajectory up to 5 years of follow-up, effects of weight loss on li
Externí odkaz:
https://doaj.org/article/e9ca233257e14999831b8f24b653eeb4
Autor:
Elizabeth S. Aby, Ghady Moafa, Nyan Latt, Mohammad T. Sultan, Paula A. Cacioppo, Sonal Kumar, Raymond T. Chung, Patricia P. Bloom, Jenna Gustafson, Michael Daidone, Zoe Reinus, Jose D. Debes, Sunny Sandhu, Aalam Sohal, Sameeha Khalid, Marina Roytman, Andreea Maria Catana, Kara Wegermann, Rotonya M. Carr, Yedidya Saiman, Ihab Kassab, Vincent L. Chen, Atoosa Rabiee, Carly Rosenberg, Veronica Nguyen, Christina Gainey, Kali Zhou, Kenneth Chavin, Blanca C. Lizaola-Mayo, David M. Chascsa, Lee Varelas, Akshata Moghe, Renumathy Dhanasekaran
Publikováno v:
Hepatology Communications, Vol 7, Iss 1, Pp e8874-e8874 (2023)
Background:. COVID-19 is associated with higher morbidity and mortality in patients with chronic liver diseases (CLDs). However, our understanding of the long-term outcomes of COVID-19 in patients with CLD is limited. Methods:. We conducted a multice
Externí odkaz:
https://doaj.org/article/c236dde342a743419230b5c9caa718bb
Autor:
Vincent L. Chen, Xiaomeng Du, Yanhua Chen, Annapurna Kuppa, Samuel K. Handelman, Rishel B. Vohnoutka, Patricia A. Peyser, Nicholette D. Palmer, Lawrence F. Bielak, Brian Halligan, Elizabeth K. Speliotes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/849fa0e898b04f6c9fd837bc969d67d0
Autor:
Vincent L. Chen, Xiaomeng Du, Yanhua Chen, Annapurna Kuppa, Samuel K. Handelman, Rishel B. Vohnoutka, Patricia A. Peyser, Nicholette D. Palmer, Lawrence F. Bielak, Brian Halligan, Elizabeth K. Speliotes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Serum liver enzyme concentrations are the most frequently-used laboratory markers of liver disease, a major cause of mortality. We conduct a meta-analysis of genome-wide association studies of liver enzymes from UK BioBank and BioBank Japan.
Externí odkaz:
https://doaj.org/article/83b170469b994a178b736003c46c40b3
Autor:
Vincent L. Chen, Daniel A. Burkholder, Isabel J. Moran, Jacob V. DiBattista, Matthew J. Miller, Yanhua Chen, Xiaomeng Du, Antonino Oliveri, Kelly C. Cushing, Anna S. Lok, Elizabeth K. Speliotes
Publikováno v:
JHEP Reports, Vol 4, Iss 6, Pp 100483- (2022)
Background & Aims: Alpha-1 antitrypsin deficiency is caused by mutations in SERPINA1, most commonly homozygosity for the Pi∗Z variant, and can present as liver disease. While heterozygosity for Pi∗Z (Pi∗MZ) is linked to increased risk of cirrho
Externí odkaz:
https://doaj.org/article/999661784190473a98decd71984b6b0f
Autor:
Vincent L. Chen, Andrew P. Wright, Brian Halligan, Yanhua Chen, Xiaomeng Du, Samuel K. Handelman, Michelle T. Long, Douglas P. Kiel, Elizabeth K. Speliotes
Publikováno v:
Hepatology Communications, Vol 3, Iss 8, Pp 1073-1084 (2019)
Up to 25% of patients with nonalcoholic fatty liver disease (NAFLD) are not obese but may have a fat or muscle composition that predisposes them to NAFLD. Our aim was to determine whether body composition parameters associate with NAFLD and to identi
Externí odkaz:
https://doaj.org/article/19e61050ca364b1f8df88f5b08129c99