Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Vincent, van Unen"'
Autor:
Li Jia, Na Li, Vincent van Unen, Jaap-Jan Zwaginga, Jerry Braun, Pieter S. Hiemstra, Frits Koning, P. Padmini S. J. Khedoe, Jan Stolk
Publikováno v:
Cells, Vol 13, Iss 19, p 1636 (2024)
Emphysema in patients with chronic obstructive pulmonary disease (COPD) is characterized by progressive inflammation. Preclinical studies suggest that lung volume reduction surgery (LVRS) and mesenchymal stromal cell (MSC) treatment dampen inflammati
Externí odkaz:
https://doaj.org/article/3b7d1e31afbb46d1b586ba30900fd01f
Autor:
Linda Voogd, Anne M.H.F. Drittij, Calinda K.E. Dingenouts, Kees L.M.C. Franken, Vincent van Unen, Krista E. van Meijgaarden, Paula Ruibal, Renate S. Hagedoorn, Judith A. Leitner, Peter Steinberger, Mirjam H.M. Heemskerk, Mark M. Davis, Thomas J. Scriba, Tom H.M. Ottenhoff, Simone A. Joosten
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109233- (2024)
Summary: HLA-E molecules can present self- and pathogen-derived peptides to both natural killer (NK) cells and T cells. T cells that recognize HLA-E peptides via their T cell receptor (TCR) are termed donor-unrestricted T cells due to restricted alle
Externí odkaz:
https://doaj.org/article/a894387ea1f243a4aa763eb88025c1d8
Autor:
Jie Ding, Sung-Jin Lee, Lukas Vlahos, Kanako Yuki, Cara C. Rada, Vincent van Unen, Meghah Vuppalapaty, Hui Chen, Asmiti Sura, Aaron K. McCormick, Madeline Tomaske, Samira Alwahabi, Huy Nguyen, William Nowatzke, Lily Kim, Lisa Kelly, Douglas Vollrath, Andrea Califano, Wen-Chen Yeh, Yang Li, Calvin J. Kuo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in disorders ranging from stroke, cancer, diabetic retinopathy, and Alzheimer’s disease. The Norrin/FZD4/TSPAN12 pathway activates WNT/β-catenin signaling,
Externí odkaz:
https://doaj.org/article/31df630cc0d74d1eb51da2d91c5e7f3c
Autor:
Emma S. Pool, Yvonne Kooy-Winkelaar, Vincent van Unen, J.H. Frederik Falkenburg, Frits Koning, Mirjam H. M. Heemskerk, Jennifer M-L. Tjon
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Idiopathic acquired aplastic anemia (AA) is considered an immune-mediated syndrome of bone marrow failure since approximately 70% of patients respond to immunosuppressive therapy (IST) consisting of a course of anti-thymocyte globulin (ATG) followed
Externí odkaz:
https://doaj.org/article/f06d662e486143c7995ea45029b7984b
Autor:
Nannan Guo, Na Li, Li Jia, Qinyue Jiang, Mette Schreurs, Vincent van Unen, Susana M. Chuva de Sousa Lopes, Alexandra A. Vloemans, Jeroen Eggermont, Boudewijn Lelieveldt, Frank J. T. Staal, Noel F. C. C. de Miranda, M. Fernanda Pascutti, Frits Koning
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The intestine is an important immunological organ in embryonic life, preparing the infant for the microbial colonization following birth. Here authors show that between gestational weeks 14 and 22, the human foetal intestine is first populated by mye
Externí odkaz:
https://doaj.org/article/bc204bc2c6094dffa261d580b254f052
Autor:
Vincent van Unen, Laura F. Ouboter, Na Li, Mette Schreurs, Tamim Abdelaal, Yvonne Kooy-Winkelaar, Guillaume Beyrend, Thomas Höllt, P. W. Jeroen Maljaars, M. Luisa Mearin, Ahmed Mahfouz, Anne M. C. Witte, Cornelis H. M. Clemens, Sunje Abraham, Johanna C. Escher, Boudewijn P. F. Lelieveldt, M. Fernanda Pascutti, Andrea E. van der Meulen – de Jong, Frits Koning
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic intestinal inflammation underlies inflammatory bowel disease (IBD). Previous studies indicated alterations in the cellular immune system; however, it has been challenging to interrogate the role of all immune cell subsets simultaneously. Ther
Externí odkaz:
https://doaj.org/article/5773beda53f54f0c94e0e199ec7a70e8
Autor:
Guillaume Beyrend, Esmé van der Gracht, Ayse Yilmaz, Suzanne van Duikeren, Marcel Camps, Thomas Höllt, Anna Vilanova, Vincent van Unen, Frits Koning, Noel F. C. C. de Miranda, Ramon Arens, Ferry Ossendorp
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background The clinical benefit of immunotherapeutic approaches against cancer has been well established although complete responses are only observed in a minority of patients. Combination immunotherapy offers an attractive avenue to develo
Externí odkaz:
https://doaj.org/article/62ddaee88fbc4b5c904b334fd5a0c621
Autor:
Anita van der Zwan, Vincent van Unen, Guillaume Beyrend, Sandra Laban, Carin van der Keur, Hanneke J. M. Kapsenberg, Thomas Höllt, Susana M. Chuva de Sousa Lopes, Marie-Louise P. van der Hoorn, Frits Koning, Frans H. J. Claas, Michael Eikmans, Sebastiaan Heidt
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
During healthy pregnancy, a balanced microenvironment at the maternal-fetal interface with coordinated interaction between various immune cells is necessary to maintain immunological tolerance. While specific decidual immune cell subsets have been in
Externí odkaz:
https://doaj.org/article/5931f59dc5b646e0a0b9fe07b354f011
Autor:
Nannan Guo, Vincent van Unen, Marieke E. Ijsselsteijn, Laura F. Ouboter, Andrea E. van der Meulen, Susana M. Chuva de Sousa Lopes, Noel F. C. C. de Miranda, Frits Koning, Na Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Imaging mass cytometry (IMC) is able to quantify the expression of dozens of markers at sub-cellular resolution on a single tissue section by combining a novel laser ablation system with mass cytometry. As such, it allows us to gain spatial informati
Externí odkaz:
https://doaj.org/article/51e04bb2c3e747548d589002420b860c
Autor:
Vincent van Unen, Thomas Höllt, Nicola Pezzotti, Na Li, Marcel J. T. Reinders, Elmar Eisemann, Frits Koning, Anna Vilanova, Boudewijn P. F. Lelieveldt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Single cell profiling yields high dimensional data of very large numbers of cells, posing challenges of visualization and analysis. Here the authors introduce a method for analysis of mass cytometry data that can handle very large datasets and allows
Externí odkaz:
https://doaj.org/article/e50b0012ac854b22b12f11d3326c67c4