Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vincent, Wiegmann"'
Publikováno v:
BioTechniques, Vol 67, Iss 5, Pp 238-241 (2019)
Aim: To investigate the impact of various feeding strategies on the growth and productivity of a GS-CHO cell line. Methods: Feed additions were conducted at fixed volumes or linked to a marker such as cell growth or metabolism and added as bolus or n
Externí odkaz:
https://doaj.org/article/0544981462e34eadb52c47b87908991e
Publikováno v:
Biotechnology and Bioengineering. 117:3018-3028
Adoptive T-cell therapy (ACT) has emerged as a promising new way to treat systemic cancers such as acute lymphoblastic leukemia. However, the robustness and reproducibility of the manufacturing process remains a challenge. Here, a single-use 24-well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d561eaef00142205f5b00529c356f3c
https://doi.org/10.1002/bit.27468
https://doi.org/10.1002/bit.27468
Publikováno v:
Biotechnology journalREFERENCES. 16(11)
Background The advancement of microbioreactor technology in recent years has transformed early- and mid-stage process development. The monitoring and control capabilities of microbioreactors not only promote the quick accumulation of process knowledg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a0cf4e49367cf222dc3ec62e823a9c
https://pubmed.ncbi.nlm.nih.gov/34494367
https://pubmed.ncbi.nlm.nih.gov/34494367
Model‐based workflow for scale‐up of process strategies developed in miniaturized bioreactor systems
Autor:
Lukas Arndt, Frank Baganz, Johannes Möller, Kim B. Kuchemüller, Ralf Pörtner, Vincent Wiegmann
Publikováno v:
Biotechnology Progress. 37
Miniaturized bioreactor (MBR) systems are routinely used in the development of mammalian cell culture processes. However, scale-up of process strategies obtained in MBR- to larger scale is challenging due to mainly non-holistic scale-up approaches. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b037359ad5df7d630e54a606ea0ed9
https://doi.org/10.1002/btpr.3122
https://doi.org/10.1002/btpr.3122
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2095
Micro-bioreactors appear frequently in today's biotechnology industry as screening and process development tools for cell culture applications. The micro-bioreactor's small volume allows for a high throughput, and when compared to other small-scale s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7956061c4f5ece33690ccee2ef0117c
https://pubmed.ncbi.nlm.nih.gov/31858463
https://pubmed.ncbi.nlm.nih.gov/31858463
Publikováno v:
Animal Cell Biotechnology ISBN: 9781071601907
Micro-bioreactors appear frequently in today's biotechnology industry as screening and process development tools for cell culture applications. The micro-bioreactor's small volume allows for a high throughput, and when compared to other small-scale s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a5c0bc8a684a48fb8f6ffa0146335a
https://doi.org/10.1007/978-1-0716-0191-4_5
https://doi.org/10.1007/978-1-0716-0191-4_5
Publikováno v:
BioTechniques. 67(5)
Aim: To investigate the impact of various feeding strategies on the growth and productivity of a GS-CHO cell line. Methods: Feed additions were conducted at fixed volumes or linked to a marker such as cell growth or metabolism and added as bolus or n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c2bc261a9241b0dcfef2c343be6093
https://pubmed.ncbi.nlm.nih.gov/31529987
https://pubmed.ncbi.nlm.nih.gov/31529987
Publikováno v:
Biotechnology letters. 40(7)
Establish a method to indirectly measure evaporation in microwell-based cell culture systems and show that the proposed method allows compensating for liquid losses in fed-batch processes. A correlation between evaporation and the concentration of Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ac869d5a9ce28c297171f6672924cb
https://pubmed.ncbi.nlm.nih.gov/29693210
https://pubmed.ncbi.nlm.nih.gov/29693210