Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Vincent, Mouly"'
Autor:
Alexis Boulinguiez, Jamila Dhiab, Barbara Crisol, Laura Muraine, Ludovic Gaut, Corentin Rouxel, Justine Flaire, Hadidja‐Rose Mouigni, Mégane Lemaitre, Benoit Giroux, Lucie Audoux, Benjamin SaintPierre, Arnaud Ferry, Vincent Mouly, Gillian Butler‐Browne, Elisa Negroni, Alberto Malerba, Capucine Trollet
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1976-1988 (2024)
Abstract Background Exercise is widely considered to have beneficial impact on skeletal muscle aging. In addition, there are also several studies demonstrating a positive effect of exercise on muscular dystrophies. Oculopharyngeal muscular dystrophy
Externí odkaz:
https://doaj.org/article/9e6f075692794eb9b63cdf6993ff5f94
Autor:
Judit Núñez-Manchón, Júlia Capó, Alicia Martínez-Piñeiro, Eduard Juanola, Jovan Pesovic, Laura Mosqueira-Martín, Klaudia González-Imaz, Pau Maestre-Mora, Renato Odria, Estefania Cerro-Herreros, Neia Naldaiz-Gastesi, Adolfo López de Munain, Rubén Artero, Dusanka Savic-Pavicevic, Ainara Vallejo-Illarramendi, Kamel Mamchaoui, Anne Bigot, Vincent Mouly, Mònica Suelves, Gisela Nogales-Gadea
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111499- (2024)
Externí odkaz:
https://doaj.org/article/dfc374e49d274f9e8fc55021794bba87
Autor:
Tayma Handal, Sarah Juster, Manar Abu Diab, Shira Yanovsky-Dagan, Fouad Zahdeh, Uria Aviel, Roni Sarel-Gallily, Shir Michael, Ester Bnaya, Shulamit Sebban, Yosef Buganim, Yotam Drier, Vincent Mouly, Stefan Kubicek, Walther J. A. A. van den Broek, Derick G. Wansink, Silvina Epsztejn-Litman, Rachel Eiges
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Epigenetic defects caused by hereditary or de novo mutations are implicated in various human diseases. It remains uncertain whether correcting the underlying mutation can reverse these defects in patient cells. Here we show by the analysis o
Externí odkaz:
https://doaj.org/article/f2f26f7be8be43019350e3bc09541979
Autor:
Francesco Galli, Laricia Bragg, Maira Rossi, Daisy Proietti, Laura Perani, Marco Bacigaluppi, Rossana Tonlorenzi, Tendai Sibanda, Miriam Caffarini, Avraneel Talapatra, Sabrina Santoleri, Mirella Meregalli, Beatriz Bano-Otalora, Anne Bigot, Irene Bozzoni, Chiara Bonini, Vincent Mouly, Yvan Torrente, Giulio Cossu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 927-944 (2024)
Abstract Cell therapy for muscular dystrophy has met with limited success, mainly due to the poor engraftment of donor cells, especially in fibrotic muscle at an advanced stage of the disease. We developed a cell-mediated exon skipping that exploits
Externí odkaz:
https://doaj.org/article/2901b421c44741348f703c80bba345e6
Autor:
Francesco Galli, Laricia Bragg, Maira Rossi, Daisy Proietti, Laura Perani, Marco Bacigaluppi, Rossana Tonlorenzi, Tendai Sibanda, Miriam Caffarini, Avraneel Talapatra, Sabrina Santoleri, Mirella Meregalli, Beatriz Bano-Otalora, Anne Bigot, Irene Bozzoni, Chiara Bonini, Vincent Mouly, Yvan Torrente, Giulio Cossu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2654-2654 (2024)
Externí odkaz:
https://doaj.org/article/5f7f0ae2ba184d8d97e0eb107a271912
Autor:
Julia Pereira Lemos, Liliane Patrícia Gonçalves Tenório, Vincent Mouly, Gillian Butler-Browne, Daniella Arêas Mendes-da-Cruz, Wilson Savino, Piera Smeriglio
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Growing evidence demonstrates a continuous interaction between the immune system, the nerve and the muscle in neuromuscular disorders of different pathogenetic origins, such as Duchenne Muscular Dystrophy (DMD) and Amyotrophic Lateral Sclerosis (ALS)
Externí odkaz:
https://doaj.org/article/6656f718bc25477db39fe5e08795f712
Autor:
Cedric Happi Mbakam, Joel Rousseau, Yaoyao Lu, Anne Bigot, Kamel Mamchaoui, Vincent Mouly, Jacques P. Tremblay
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 272-285 (2022)
Duchenne muscular dystrophy is a severe debilitating genetic disease caused by different mutations in the DMD gene leading to the absence of dystrophin protein under the sarcolemma. We used CRISPR-Cas9 prime editing technology for correction of the c
Externí odkaz:
https://doaj.org/article/53e3d0650e5c4b7db33a69417ae6c1a1
Autor:
Cedric Happi Mbakam, Jeanne Roustant, Joel Rousseau, Pouire Yameogo, Yaoyao Lu, Anne Bigot, Kamel Mamchaoui, Vincent Mouly, Gabriel Lamothe, Jacques P. Tremblay
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Duchenne muscular dystrophy is a rare and lethal hereditary disease responsible for progressive muscle wasting due to mutations in the DMD gene. We used the CRISPR-Cas9 Prime editing technology to develop different strategies to correct frameshift mu
Externí odkaz:
https://doaj.org/article/a835f08bd75b4b848f7c08256e27f334
Autor:
Eline Lemerle, Jeanne Lainé, Marion Benoist, Gilles Moulay, Anne Bigot, Clémence Labasse, Angéline Madelaine, Alexis Canette, Perrine Aubin, Jean-Michel Vallat, Norma B Romero, Marc Bitoun, Vincent Mouly, Isabelle Marty, Bruno Cadot, Laura Picas, Stéphane Vassilopoulos
Publikováno v:
eLife, Vol 12 (2023)
Excitation-contraction coupling requires a highly specialized membrane structure, the triad, composed of a plasma membrane invagination, the T-tubule, surrounded by two sarcoplasmic reticulum terminal cisternae. Although the precise mechanisms govern
Externí odkaz:
https://doaj.org/article/30988e26f18d4cc88809cbec0d185677
Autor:
Mona Bensalah, Laura Muraine, Alexis Boulinguiez, Lorenzo Giordani, Victorine Albert, Victor Ythier, Jamila Dhiab, Alison Oliver, Valentine Hanique, Teresa Gidaro, Sophie Perié, Jean Lacau St‐Guily, Aurélien Corneau, Gillian Butler‐Browne, Anne Bigot, Vincent Mouly, Elisa Negroni, Capucine Trollet
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1771-1784 (2022)
Abstract Background Fibrosis is defined as an excessive accumulation of extracellular matrix (ECM) components. Many organs are subjected to fibrosis including the lung, liver, heart, skin, kidney, and muscle. Muscle fibrosis occurs in response to tra
Externí odkaz:
https://doaj.org/article/7c62485f71544d54a83dad75fc3fe420