Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Vincent, Goffin"'
Autor:
Emma Cosialls, Emeline Pacreau, Clémence Duruel, Sara Ceccacci, Rima Elhage, Christophe Desterke, Kevin Roger, Chiara Guerrera, Romane Ducloux, Sylvie Souquere, Gérard Pierron, Ivan Nemazanyy, Mairead Kelly, Elise Dalmas, Yunhua Chang, Vincent Goffin, Maryam Mehrpour, Ahmed Hamaï
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Ferroptosis constitutes a promising therapeutic strategy against cancer by efficiently targeting the highly tumorigenic and treatment-resistant cancer stem cells (CSCs). We previously showed that the lysosomal iron-targeting drug Salinomycin
Externí odkaz:
https://doaj.org/article/5ad5e737bb114cf494300de72b4fe890
Autor:
Jan Pencik, Cecile Philippe, Michaela Schlederer, Emine Atas, Matteo Pecoraro, Sandra Grund-Gröschke, Wen (Jess) Li, Amanda Tracz, Isabel Heidegger, Sabine Lagger, Karolína Trachtová, Monika Oberhuber, Ellen Heitzer, Osman Aksoy, Heidi A. Neubauer, Bettina Wingelhofer, Anna Orlova, Nadine Witzeneder, Thomas Dillinger, Elisa Redl, Georg Greiner, David D’Andrea, Johnny R. Östman, Simone Tangermann, Ivana Hermanova, Georg Schäfer, Felix Sternberg, Elena E. Pohl, Christina Sternberg, Adam Varady, Jaqueline Horvath, Dagmar Stoiber, Tim I. Malcolm, Suzanne D. Turner, Eileen E. Parkes, Brigitte Hantusch, Gerda Egger, Stefan Rose-John, Valeria Poli, Suneil Jain, Chris W. D. Armstrong, Gregor Hoermann, Vincent Goffin, Fritz Aberger, Richard Moriggl, Arkaitz Carracedo, Cathal McKinney, Richard D. Kennedy, Helmut Klocker, Michael R. Speicher, Dean G. Tang, Ali A. Moazzami, David M. Heery, Marcus Hacker, Lukas Kenner
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-25 (2023)
Abstract Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa) is a major factor contributing to its lethality, although the mechanisms remain poorly understood. PTEN is one of the most frequently deleted genes in m
Externí odkaz:
https://doaj.org/article/55713eefba5d493d89c7d396451b3eb7
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/56c28fcff37d4353bb55d1a2cca71d54
Autor:
Pilar Flores-Espinosa, Isabel Méndez, Claudine Irles, Andrea Olmos-Ortiz, Cecilia Helguera-Repetto, Ismael Mancilla-Herrera, Daniel Ortuño-Sahagún, Vincent Goffin, Verónica Zaga-Clavellina
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The close interaction between fetal and maternal cells during pregnancy requires multiple immune-endocrine mechanisms to provide the fetus with a tolerogenic environment and protection against any infectious challenge. The fetal membranes and placent
Externí odkaz:
https://doaj.org/article/df5b46d400034ae58aad6145cca2d26e
Autor:
Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jérémy Guehennec, Louis Royer‐Perron, Jean‐Léon Thomas, TuKiet T. Lam, Florent Dingli, Damarys Loew, François Ducray, Sophie Paris, Catherine Carpentier, Yannick Marie, Florence Laigle‐Donadey, Audrey Rousseau, Natascha Pigat, Florence Boutillon, Franck Bielle, Karima Mokhtari, Stuart J. Frank, Aurélien deReyniès, Khê Hoang‐Xuan, Marc Sanson, Vincent Goffin, Ahmed Idbaih
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Objective New therapeutic approaches are needed to improve the prognosis of glioblastoma (GBM) patients. Methods With the objective of identifying alternative oncogenic mechanisms to abnormally activated epidermal growth factor receptor (EGF
Externí odkaz:
https://doaj.org/article/eda0001ce8334a88897701a1bbcf3626
Autor:
Virginie Grouthier, Zeina Chakhtoura, Isabelle Tejedor, Yasmina Badachi, Vincent Goffin, Philippe Touraine
Publikováno v:
Endocrine Connections, Vol 9, Iss 6, Pp 570-577 (2020)
Objective: Multiple fibroadenomas (MFA) of the breast is a rare benign dis ease, thus its natural history is poorly understood. The aim of our study was to describe the radiological evolution of MFA and to evaluate the influence of d ifferent factors
Externí odkaz:
https://doaj.org/article/2abd14c9a0f14d21838bfa1129869749
Autor:
Charles Dariane, Manon Baures, Julien Anract, Nicolas Barry Delongchamps, Jacques-Emmanuel Guidotti, Vincent Goffin
Publikováno v:
médecine/sciences. 39:429-436
Les traitements médicaux de l’hyperplasie bénigne et du cancer de la prostate reposent essentiellement sur l’inhibition de la signalisation androgénique. Bien qu’initialement efficaces, ces traitements sont tôt ou tard confrontés à une r
Autor:
Mayur Patil, Sergei Belugin, Jennifer Mecklenburg, Andi Wangzhou, Candler Paige, Priscilla A. Barba-Escobedo, Jacob T. Boyd, Vincent Goffin, David Grattan, Ulrich Boehm, Gregory Dussor, Theodore J. Price, Armen N. Akopian
Publikováno v:
iScience, Vol 20, Iss , Pp 449-465 (2019)
Summary: Many clinical and preclinical studies report an increased prevalence and severity of chronic pain among females. Here, we identify a sex-hormone-controlled target and mechanism that regulates dimorphic pain responses. Prolactin (PRL), which
Externí odkaz:
https://doaj.org/article/480a911199dc475b90157a763911ad44
Autor:
Nicolas Barry Delongchamps, Alexandre Schull, Julien Anract, Jean-Paul Abecassis, Marc Zerbib, Mathilde Sibony, Léa Jilet, Hendy Abdoul, Vincent Goffin, Michaël Peyromaure
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0252040 (2021)
ObjectiveTo assess the feasibility, safety and precision of organ-based tracking (OBT)-fusion targeted focal microwave ablation (FMA), in patients with low to intermediate risk prostate cancer.Patients and methodTen patients with a visible index tumo
Externí odkaz:
https://doaj.org/article/50141246603f4b8d862722c30eafdc00
Publikováno v:
Endocrinology.
Hyperprolactinemia is prevalent in up to 16% of the infertile males. Although prolactin receptor (PRLR) is present on various testicular cells, the physiological role of this receptor in spermatogenesis remains elusive. The aim of this study is to de