Sex‐Based Differences in the Performance of the HEART Score in Patients Presenting to the Emergency Department With Acute Chest Pain

Autor: Ingrid E. M. Bank, Vince C. de Hoog, Dominique P. V. de Kleijn, Gerard Pasterkamp, Pieter A. Doevendans, Hester M. den Ruijter, Geertje Dalmeijer, Thierry X. Wildbergh, Arend Mosterd, Leo Timmers

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)

BackgroundSex‐based differences in clinical presentation, pathophysiology, and outcomes of patients with acute chest pain are increasingly being recognized, but are not implemented in guidelines and clinical prediction tools. We evaluated the perfo

Externí odkaz: https://doaj.org/article/b9fb94f768e44ab4a09691f1ff339352

Ethnic differences in clinical outcome of patients presenting to the emergency department with chest pain

Autor: Ingrid E M Bank, Thierry X. Wildbergh, Fei Gao, Crystel M. Gijsberts, Gerard Pasterkamp, Swee Han Lim, A. Mark Richards, Pieter A. Doevendans, Arend Mosterd, Hester M. den Ruijter, Dominique P.V. de Kleijn, Win Sen Kuan, Terrance Chua, Irwani Ibrahim, Shirley B.S. Ooi, Leo Timmers, Vince C de Hoog, E. Shyong Tai

Publikováno v: European Heart Journal: Acute Cardiovascular Care. 5:32-40

Ethnicity, although known to influence cardiovascular outcome in assorted clinical settings, has not been investigated previously as a risk factor in patients presenting to the emergency department with suspected acute myocardial infarction.In this m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f88fccf31e6a237bb0ace12cc7477e6
https://doi.org/10.1177/2048872615623064

Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury

Autor: Leo Timmers, Vince C. de Hoog, Amerik van Duijvenvoorde, Mirjam B. Smeets, Dominique P.V. de Kleijn, Pieter A. Doevendans, Saskia C.A. de Jager, Ben van Middelaar, Gerard Pasterkamp, C. Erik Hack, Trent M. Woodruff

Publikováno v: Cardiovascular research. 103(4)

Aims Early reperfusion is mandatory for the treatment of acute myocardial infarction. This process, however, also induces additional loss of viable myocardium, called ischaemia–reperfusion (IR) injury. Complement activation plays an important role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7834cd8c8be50f0af377edb99be2045
https://pubmed.ncbi.nlm.nih.gov/24935433

The innate immune response in reperfused myocardium

Autor: Yolande Appelman, Gerard Pasterkamp, Leo Timmers, Vince C de Hoog, Fatih Arslan, Dominique P.V. de Kleijn

Publikováno v: Timmers, L, Pasterkamp, G, de Hoog, V C, Arslan, F, Appelman, Y E A & de Kleijn, D P V 2012, ' The innate immune response in reperfused myocardium ', Cardiovascular Research, vol. 94, no. 2, pp. 276-283 . https://doi.org/10.1093/cvr/cvs018
Cardiovascular Research, 94(2), 276-283. Oxford University Press

One of the major therapeutic challenges in the arena of interventional cardiology is to design strategies aimed at reducing myocardial tissue damage after myocardial infarction. In response to tissue injury, an innate immune response is initiated tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b5eb48b0a1f8507c63579379ff9c5e
https://research.vumc.nl/en/publications/1e41ce44-f0c5-4cbc-8e74-816f20a50519