Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Vinayakumar Gedi"'
Advanced Bioluminescence Reporter with Engineered Gaussia Luciferase via Sequence-Guided Mutagenesis
Publikováno v:
Biosensors, Vol 14, Iss 11, p 528 (2024)
Gaussia luciferase (GLuc) is the preeminent secreted luciferase widely used in cell-based reporter assays. By employing sequence-guided mutagenesis informed by alignments of diverse copepod luciferase sequences, we identified key amino acids that sig
Externí odkaz:
https://doaj.org/article/d11470965add44eebda8203072de84bb
Autor:
Shuo Ren, Samuel Cho, Ruixan Lin, Vinayakumar Gedi, Sunyoung Park, Chul Woo Ahn, Dong-Ki Lee, Min-Ho Lee, Sangwook Lee, Soyoun Kim
Publikováno v:
Biosensors, Vol 12, Iss 10, p 864 (2022)
Spiegelmers are enantiomers of natural D-oligonucleotides that bind to targets with distinct structures such as aptamers. The high susceptibility of natural D-form aptamers to nucleases greatly hinders their application in biological environments. He
Externí odkaz:
https://doaj.org/article/3ddb0f5cb4ef443492ebf1363c2863b4
Autor:
Vinayakumar Gedi, Young-Pil Kim
Publikováno v:
Sensors, Vol 14, Iss 10, Pp 18302-18327 (2014)
Detection and characterization of cells using aptamers and aptamer-conjugated nanoprobes has evolved a great deal over the past few decades. This evolution has been driven by the easy selection of aptamers via in vitro cell-SELEX, permitting sensitiv
Externí odkaz:
https://doaj.org/article/c1cb9f95a6974974862049396f63f8a4
Autor:
Jin Oh Lee, Mingi Jung, Chung Kil Song, Haiwon Lee, Vinayakumar Gedi, Jinhee Shim, Young-Pil Kim, Gae Baik Kim, Bum Seok Shin, Eunkyul Oh
Publikováno v:
Sensors and Actuators B: Chemical. 256:89-97
Despite the major role of cancer antigen 125 (CA125) in cancer progression, its structural diversity makes antibody-based immunoassay of this protein difficult. Here we report the selection of an anti-CA125 ssDNA aptamer and its application to sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d74a71fc14beb74e27997edfd4349143
https://doi.org/10.1016/j.snb.2017.10.049
https://doi.org/10.1016/j.snb.2017.10.049
Publikováno v:
Bulletin of the Korean Chemical Society. 38:324-328
Botulinum neurotoxins (BoNTs) produced by Clostridium botulinum are the deadliest toxins known to mankind with a potential of possible bioterrorism agents. Due to the high-potential harm of these toxins, a sensitive and real-time monitoring capable d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed94ab6a78a6cabe15d0c77616528db
https://doi.org/10.1002/bkcs.11085
https://doi.org/10.1002/bkcs.11085
Autor:
Kwang-jick Lee, Byung-Hoon Cho, Su-Jeong Park, Chae-mi Lim, Min-Kyoung Kim, Hae-Chul Park, Myeong-Ae Kim, JeongWoo Kang, Hyun-Jung Kwon, Tae-Wan Kim, Vinayakumar Gedi
Publikováno v:
Food Additives & Contaminants: Part B. 8:106-112
The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test programme. Monitoring and surveillance/enforcement te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a95ffb0a20c01a4bcb9d2019d87e6a
https://doi.org/10.1080/19393210.2014.1001795
https://doi.org/10.1080/19393210.2014.1001795
Autor:
June-Haeng Cho, Moon-Young Yoon, Kwang-jick Lee, Byung-Jae So, JeongWoo Kang, Hae-Chul Park, Jae-Wook Hyun, Vinayakumar Gedi
Publikováno v:
Applied Biochemistry and Biotechnology. 172:3263-3270
FtsZ is an essential bacterial cell division protein that is an attractive target for the development of antibacterial agents. FtsZ is a homologue of eukaryotic tubulin, has GTPase activity, and forms a ring-type structure to initiate cell division.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddca3c3717c6219e4ece306b0d118f8
https://doi.org/10.1007/s12010-014-0752-2
https://doi.org/10.1007/s12010-014-0752-2
Autor:
Vinayakumar Gedi, Moon-Young Yoon
Publikováno v:
FEBS Journal. 279:946-963
Acetohydroxyacid synthase (anabolic AHAS; EC 2.2.1.6) is a thiamin diphosphate-dependent enzyme that catalyzes the first step in the branched-chain amino acid (BCAA) biosynthesis pathway. BCAAs are synthesized by plants, algae, fungi and bacteria, al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d1cc4017ca83ee3a0acddf6bf288e8
https://doi.org/10.1111/j.1742-4658.2012.08505.x
https://doi.org/10.1111/j.1742-4658.2012.08505.x
Publikováno v:
Advanced Materials. 23:5425-5429
A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688a25ca1ad4854b36451b0aeca22740
https://doi.org/10.1002/adma.201103284
https://doi.org/10.1002/adma.201103284
Autor:
Joungmok Kim, Hae-Chul Park, Arthur G. Roberts, Hye Yeon Park, Vinayakumar Gedi, Moon Young Yoon, William M. Atkins
Publikováno v:
Biochemical and Biophysical Research Communications. 404:517-522
Inhibitors of anthrax lethal factor (LF) are currently being sought as effective therapeutics for the treatment of anthrax. Here we report a novel screening approach for inhibitors of LF, a yeast-hybrid-based assay system in which the expression of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96c8500f7e732b7664fbf8f036eb946
https://doi.org/10.1016/j.bbrc.2010.12.015
https://doi.org/10.1016/j.bbrc.2010.12.015