Circulating Gut Microbe-Derived Metabolites Are Associated with Hepatocellular Carcinoma

Autor: Rakhee Banerjee, Chase J. Wehrle, Zeneng Wang, Jennifer D. Wilcox, Vinayak Uppin, Venkateshwari Varadharajan, Marko Mrdjen, Courtney Hershberger, Ofer Reizes, Jennifer S. Yu, Justin D. Lathia, Daniel M. Rotroff, Stanley L. Hazen, W. H. Wilson Tang, Federico Aucejo, J. Mark Brown

Publikováno v: Biomedicines, Vol 12, Iss 9, p 1946 (2024)

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. The gut microbiome has been implicated in outcomes for HCC, and gut microbe-derived products may serve as potential non-invasive indices for early HCC detection. Thi

Externí odkaz: https://doaj.org/article/a62200dc1b60493abf45e69dac2752b1

Withaferin-A down-regulate enterohepatic circulation of bile acids: An insight from a hyperlipidemic rat model

Autor: Pooja Acharya, Parvati Huded, Sadashivaiah Bettadahalli, Mehrdad Zarei, Vinayak Uppin, Nayana Venugopal, Ramaprasad Ravichandra Talahalli

Publikováno v: Journal of Agriculture and Food Research, Vol 2, Iss , Pp 100035- (2020)

Hyperlipidemia is a metabolic abnormality in both young and aged populations across the world. Withaferin-A (WT) present in Withania somnifera (Indian ginseng) has been studied by many investigators for their therapeutic potentials. However, their ef

Externí odkaz: https://doaj.org/article/be1eef719afd4f1eb0aa6ac67f29b608

Crack suppression by natural fiber integration for improved interlaminar fracture toughness in fiber hybrid composites

Autor: Abhilash Edacherian, Nabaneeta Gogoi, Jyoti Vastrad, Vinayak Uppin, Umarfarooq M A, Sridhar I, Anant Joshi, Shivakumar Gouda

Publikováno v: Frattura ed Integrità Strutturale; Vol. 16 No. 60 (2022): April 2022; 158-173
Frattura ed Integrità Strutturale; V. 16 N. 60 (2022): April 2022; 158-173

In this paper, the effect of integration of natural fibers in UD carbon fiber is studied. The integration of natural fibers in carbon fiber is made via intra fiber hybridization. Natural fiber hybrid composite samples were prepared for Mode I and Mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f77a55e3d69a12569be07bb8fa4f56
https://doi.org/10.3221/igf-esis.60.12

Ginger and turmeric lipid-solubles attenuate heated oil-induced oxidative stress in the brain via the upregulation of NRF2 and improve cognitive function in rats

Autor: Pooja Acharya, Vinayak Uppin, Ramaprasad Ravichandra Talahalli, Mehrdad Zarei

Publikováno v: Metabolic Brain Disease. 36:225-238

In this study, we elucidated the modulatory potentials of lipid-solubles from ginger and turmeric that may migrate to oils during heating on the brain antioxidant defense and cognitive response in rats. Male Wistar rats were fed with control diet [in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e87652aaee94a7213d01bb1877b7ee
https://doi.org/10.1007/s11011-020-00642-y

Water soluble polysaccharides from Spirulina platensis exhibited cyto/DNA protection and suppress the growth of gastric cancer cells via modulation of galectin-3

Autor: Vinayak Uppin, Shylaja M Dharmesh, R Sarada

Polysaccharides from natural sources play a significant role in the management of different cancer types including gastric cancer. In this study, we reported the effect of spirulina polysaccharide (Sp) on galectin-3 modulatory activity on gastric can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5c5980dd898a3989cef36f68c2a2d47
https://doi.org/10.1101/2021.12.16.473001