Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Vinayak Harihar"'
Autor:
Young-hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Seung-Min Bae, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Benjamin P. Kleinstiver, Jungjoon K. Lee, Taekjip Ha, Hyongbum Henry Kim
Publikováno v:
Nature Chemical Biology.
Although several high-fidelity SpCas9 variants have been reported, it has been observed that this increased specificity is associated with reduced on-target activity, limiting the applications of the high-fidelity variants when efficient genome editi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6d9dae292d0c5be30f3cab4e636d2e
https://doi.org/10.1038/s41589-023-01279-5
https://doi.org/10.1038/s41589-023-01279-5
Autor:
Young-hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Jungjoon K. Lee, Taekjip Ha, Hyongbum Henry Kim
Although several high-fidelity SpCas9 variants that have reduced activities at mismatched target sequences have been reported, it has been observed that this increased specificity is associated with reduced on-target activity, limiting the applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c07511677842f72aabc038526728dd
https://doi.org/10.1101/2022.12.05.519240
https://doi.org/10.1101/2022.12.05.519240
