Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Vinay K. Puduvalli"'
Autor:
Pratibha Sharma, Vinay K. Puduvalli
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103159- (2024)
Summary: Glioma cells switch between energetic pathways to adapt and resist therapies. We present a protocol for measuring mitochondrial and glycolytic ATP rates in patient-derived glioma stem-like cells using a Seahorse XF ATP rate assay. We describ
Externí odkaz:
https://doaj.org/article/a34bca8295ff40adb769c66dcd60263e
Autor:
Sheng Zhong, Wenzhuo Yang, Zhiyun Zhang, Yangyiran Xie, Lin Pan, Jiaxin Ren, Fei Ren, Yifan Li, Haoqun Xie, Hongyu Chen, Davy Deng, Jie Lu, Hui Li, Bo Wu, Youqi Chen, Fei Peng, Vinay K. Puduvalli, Ke Sai, Yunqian Li, Ye Cheng, Yonggao Mou
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Glioma is one of the leading types of brain tumor, but few etiologic factors of primary glioma have been identified. Previous observational research has shown an association between viral infection and glioma risk. In this study,
Externí odkaz:
https://doaj.org/article/d18757cc3c924ae4be725c709b8b5a6c
Autor:
Afzal Khan, Muhammad Ikram, Sadia Rehman, Rizwan Khan, Vinay K. Puduvalli, Ayub Jadoon, Momin Khan, Fawaz Alasmari, Abdullah F. AlAsmari
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17601- (2023)
Glioblastoma multiforme (GBM) is the most common and primary brain tumor with poor prognosis. They are removed by following tedious and life threatening surgeries. GBM stem cells (GSCs) are the main source of tumor recurrence after surgery. Hence, dr
Externí odkaz:
https://doaj.org/article/8484eaa87cb14f47b29d8df040fb16e5
Autor:
Hannah Rinehardt, Mahmoud Kassem, Evan Morgan, Marilly Palettas, Julie A. Stephens, Anupama Suresh, Akansha Ganju, Maryam Lustberg, Robert Wesolowski, Sagar Sardesai, Daniel Stover, Jeffrey Vandeusen, Mathew Cherian, Maria del Pilar Guillermo Prieto Eibl, Abdul Miah, Iyad Alnahhas, Pierre Giglio, Vinay K. Puduvalli, Bhuvaneswari Ramaswamy, Nicole Williams, Anne M. Noonan
Publikováno v:
European Journal of Breast Health, Vol 17, Iss 4, Pp 371-377 (2021)
Objective:Leptomeningeal carcinomatosis (LMC), a common complication of advanced malignancies, is associated with high morbidity and mortality, yet diagnosis and treatment decisions remain challenging. This study describes the diagnostic and treatmen
Externí odkaz:
https://doaj.org/article/22c7faaf894846a1b01de6c095b3ff82
Autor:
Jiyong Liang, Dexing Fang, Joy Gumin, Hinda Najem, Moloud Sooreshjani, Renduo Song, Aria Sabbagh, Ling-Yuan Kong, Joseph Duffy, Irina V. Balyasnikova, Seth M. Pollack, Vinay K. Puduvalli, Amy B. Heimberger
Publikováno v:
Cancers, Vol 15, Iss 4, p 1085 (2023)
Background: Chimeric antigen receptor (CAR) T cells have recently been demonstrated to extract and express cognate tumor antigens through trogocytosis. This process may contribute to tumor antigen escape, T cell exhaustion, and fratricide, which play
Externí odkaz:
https://doaj.org/article/6c27abbcf6ee4b3abcefceb0f164baec
Autor:
Na Tosha N. Gatson, Jill Barnholtz-Sloan, Jan Drappatz, Roger Henriksson, Andreas F. Hottinger, Piet Hinoul, Carol Kruchko, Vinay K. Puduvalli, David D. Tran, Eric T. Wong, Martin Glas
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe COVID-19 pandemic has placed excessive strain on health care systems and is especially evident in treatment decision-making for cancer patients. Glioblastoma (GBM) patients are among the most vulnerable due to increased incidence in the
Externí odkaz:
https://doaj.org/article/bb11cabf61264759a7f38223692b2f5d
Autor:
Alessandra M. Welker, Brian D. Jaros, Vinay K. Puduvalli, Jaime Imitola, Balveen Kaur, Christine E. Beattie
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 2, Pp 199-210 (2016)
Glioblastoma (GBM) is a deadly brain cancer, for which few effective drug treatments are available. Several studies have used zebrafish models to study GBM, but a standardized approach to modeling GBM in zebrafish was lacking to date, preventing comp
Externí odkaz:
https://doaj.org/article/d3efdfac277e453faa9915369e8cc89c
Autor:
Alessandra M. Welker, Brian D. Jaros, Vinay K. Puduvalli, Jaime Imitola, Balveen Kaur, Christine E. Beattie
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 9, Pp 1063-1065 (2016)
Externí odkaz:
https://doaj.org/article/8370d7bc0e254bb58ac1a7d4d296cd34
Autor:
Craig Horbinski, Louis Burt Nabors, Jana Portnow, Joachim Baehring, Ankush Bhatia, Orin Bloch, Steven Brem, Nicholas Butowski, Donald M. Cannon, Samuel Chao, Milan G. Chheda, Andrew J. Fabiano, Peter Forsyth, Pierre Gigilio, Jona Hattangadi-Gluth, Matthias Holdhoff, Larry Junck, Thomas Kaley, Ryan Merrell, Maciej M. Mrugala, Seema Nagpal, Lucien A. Nedzi, Kathryn Nevel, Phioanh L. Nghiemphu, Ian Parney, Toral R. Patel, Katherine Peters, Vinay K. Puduvalli, Jason Rockhill, Chad Rusthoven, Nicole Shonka, Lode J. Swinnen, Stephanie Weiss, Patrick Yung Wen, Nicole E. Willmarth, Mary Anne Bergman, Susan Darlow
Publikováno v:
Journal of the National Comprehensive Cancer Network. 21:12-20
The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of the following adult CNS cancers: glioma (WHO grade 1, WHO grade 2–3 oligodendroglioma [1p19q codeleted, IDH-mutant], WHO grade 2–4 IDH-mutant astrocytoma, WHO gra
Autor:
Farshad Nassiri, Vikas Patil, Leeor S. Yefet, Olivia Singh, Jeff Liu, Rachel M. A. Dang, Takafumi N. Yamaguchi, Mariza Daras, Timothy F. Cloughesy, Howard Colman, Priya U. Kumthekar, Clark C. Chen, Robert Aiken, Morris D. Groves, Shirley S. Ong, Rohan Ramakrishna, Michael A. Vogelbaum, Simon Khagi, Thomas Kaley, Jason M. Melear, David M. Peereboom, Analiz Rodriguez, Maxim Yankelevich, Suresh G. Nair, Vinay K. Puduvalli, Kenneth Aldape, Andrew Gao, Álvaro López-Janeiro, Carlos E. de Andrea, Marta M. Alonso, Paul Boutros, Joan Robbins, Warren P. Mason, Adam M. Sonabend, Roger Stupp, Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Gelareh Zadeh
Publikováno v:
Nature Medicine.
Immune-mediated anti-tumoral responses, elicited by oncolytic viruses and augmented with checkpoint inhibition, may be an effective treatment approach for glioblastoma. Here in this multicenter phase 1/2 study we evaluated the combination of intratum