Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vinay K Godena"'
Autor:
Vinay K Godena, Giulia Romano, Maurizio Romano, Chiara Appocher, Raffaella Klima, Emanuele Buratti, Francisco E Baralle, Fabian Feiguin
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17808 (2011)
TDP-43 is an evolutionarily conserved RNA binding protein recently associated with the pathogenesis of different neurological diseases. At the moment, neither its physiological role in vivo nor the mechanisms that may lead to neurodegeneration are we
Externí odkaz:
https://doaj.org/article/647592efbc1d43ccb692b979ee1f6c23
Autor:
Evangelia Karyka, Nelly Berrueta Ramirez, Christopher P Webster, Paolo M Marchi, Emily J Graves, Vinay K Godena, Lara Marrone, Anushka Bhargava, Swagat Ray, Ke Ning, Hannah Crane, Guillaume M Hautbergue, Sherif F El-Khamisy, Mimoun Azzouz
Publikováno v:
Life science alliance. 5(8)
Spinal muscular atrophy, the leading genetic cause of infant mortality, is a motor neuron disease caused by low levels of survival motor neuron (SMN) protein. SMN is a multifunctional protein that is implicated in numerous cytoplasmic and nuclear pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d46e398b54386c1303922357ff4aa0
https://pubmed.ncbi.nlm.nih.gov/35440492
https://pubmed.ncbi.nlm.nih.gov/35440492
Publikováno v:
Human Molecular Genetics
Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons resulting in a catastrophic loss of motor function. Current therapies are severely limited owing to a poor mechanistic understanding of the pathobiology. Mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f19fb299614b2a12e192c9affaf6647
http://europepmc.org/articles/PMC5181624
http://europepmc.org/articles/PMC5181624
Autor:
Vinay K. Godena, Ke Ning
Publikováno v:
Signal Transduction and Targeted Therapy
Spinal muscular atrophy (SMA) is one of the most common juvenile neurodegenerative diseases, which can be associated with child mortality. SMA is caused by a mutation of ubiquitously expressed gene, Survival Motor Neuron1 (SMN1), leading to reduced S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0106956e8d872d183091d70fd2b261c4
https://doi.org/10.1038/sigtrans.2017.38
https://doi.org/10.1038/sigtrans.2017.38
Autor:
Raffaella Klima, Andrea D’Ambrogio, Fabian Feiguin, Francisco E. Baralle, Giulia Romano, Vinay K. Godena
Publikováno v:
FEBS Letters. 583:1586-1592
Pathological modifications in the highly conserved and ubiquitously expressed heterogeneous ribonucleoprotein TDP-43 were recently associated to neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), a late-onset disorder that affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dca2f6bff3ad868756482f466483afb
https://doi.org/10.1016/j.febslet.2009.04.019
https://doi.org/10.1016/j.febslet.2009.04.019
Publikováno v:
Human Molecular Genetics
Mutations in VPS35 (PARK17) cause autosomal dominant, late onset Parkinson's disease (PD). VPS35 forms a core component of the retromer complex that mediates the retrieval of membrane proteins from endosomes back to either the Golgi or plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf8e79e24bcade205163d9851cc97cb
https://pubmed.ncbi.nlm.nih.gov/26251041
https://pubmed.ncbi.nlm.nih.gov/26251041
Autor:
Elena Ziviani, Alexander J. Whitworth, Alvaro Sanchez-Martinez, Vinay K. Godena, Rachael M. Ivatt, Stephen Brown
Significance This study presents the first results, to our knowledge, of a whole-genome RNAi screen to identify factors that promote Parkin-mediated mitophagy, which have been validated for conservation across species. Top hits comprise several compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b8b124dc9cc7d11987b0dc71a91abf
https://europepmc.org/articles/PMC4060696/
https://europepmc.org/articles/PMC4060696/
Autor:
Alexander J. Whitworth, Luigi Bubacco, Alice Biosa, Mariano Beltramini, Alvaro Sanchez-Martinez, Vinay K. Godena, Marco Bisaglia, Filograna Roberta
Publikováno v:
Parkinsonism & Related Disorders. 22:e88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eddf8d680a22821cb7bc57404c9f91f2
https://doi.org/10.1016/j.parkreldis.2015.10.182
https://doi.org/10.1016/j.parkreldis.2015.10.182
Autor:
Maurizio Romano, Vinay K. Godena, Raffaella Klima, Fabian Feiguin, Chiara Appocher, Emanuele Buratti, Giulia Romano, Francisco E. Baralle
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17808 (2011)
PLoS ONE
PLoS ONE
TDP-43 is an evolutionarily conserved RNA binding protein recently associated with the pathogenesis of different neurological diseases. At the moment, neither its physiological role in vivo nor the mechanisms that may lead to neurodegeneration are we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17ad4fafb112a62e2dc25a94414f607
http://europepmc.org/articles/PMC3055892?pdf=render
http://europepmc.org/articles/PMC3055892?pdf=render