Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vinay J. Rao"'
Autor:
Robert Lesurf, Abdelrahman Said, Oyediran Akinrinade, Jeroen Breckpot, Kathleen Delfosse, Ting Liu, Roderick Yao, Gabrielle Persad, Fintan McKenna, Ramil R. Noche, Winona Oliveros, Kaia Mattioli, Shreya Shah, Anastasia Miron, Qian Yang, Guoliang Meng, Michelle Chan Seng Yue, Wilson W. L. Sung, Bhooma Thiruvahindrapuram, Jane Lougheed, Erwin Oechslin, Tapas Mondal, Lynn Bergin, John Smythe, Shashank Jayappa, Vinay J. Rao, Jayaprakash Shenthar, Perundurai S. Dhandapany, Christopher Semsarian, Robert G. Weintraub, Richard D. Bagnall, Jodie Ingles, Genomics England Research Consortium, Marta Melé, Philipp G. Maass, James Ellis, Stephen W. Scherer, Seema Mital
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Cardiomyopathy (CMP) is a heritable disorder. Over 50% of cases are gene-elusive on clinical gene panel testing. The contribution of variants in non-coding DNA elements that result in cryptic splicing and regulate gene expression has not bee
Externí odkaz:
https://doaj.org/article/98efc3d1863c49afbe226a84a5eb5c6f
Autor:
Darshini A. Desai, Vinay J. Rao, Anil G. Jegga, Perundurai S. Dhandapany, Sakthivel Sadayappan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Myosin binding protein-C (MyBP-C) is a sarcomeric protein which regulates the force of contraction in striated muscles. Mutations in the MYBPC family of genes, including slow skeletal (MYBPC1), fast skeletal (MYBPC2) and cardiac (MYBPC3), can result
Externí odkaz:
https://doaj.org/article/864e01194e4f4bffa6a86b5a7b3b1d16
Autor:
Pratul Kumar Jain, Shashank Jayappa, Thiagarajan Sairam, Anupam Mittal, Sayan Paul, Vinay J Rao, Harshil Chittora, Deepak K Kashyap, Dasaradhi Palakodeti, Kumarasamy Thangaraj, Jayaprakash Shenthar, Rakesh Koranchery, Ranjith Rajendran, Haghighi Alireza, Kurukkanparampil Sreedharan Mohanan, Andiappan Rathinavel, Perundurai S Dhandapany
Publikováno v:
Journal of Medical Genetics. 59:984-992
BackgroundHypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease with preserved or increased ejection fraction in the absence of secondary causes. Mutations in the sarcomeric protein-encoding genes predominantly cause HCM. However, relat
Autor:
Akash K. Singh, Sin H. Neo, Christine Liwang, Karen K. L. Pang, Jason C. K. Leng, Sarmistha H. Sinha, Mahesh S. Shetty, Madavan Vasudevan, Vinay J. Rao, Ila Joshi, Muthusamy Eswaramoorthy, Maria V. Pavon, Ang R. Sheila, Sheeja Navakkode, Tapas K. Kundu, Sreedharan Sajikumar
Publikováno v:
Aging cell. 21(9)
The master epigenetic regulator lysine acetyltransferase (KAT) p300/CBP plays a pivotal role in neuroplasticity and cognitive functions. Recent evidence has shown that in several neurodegenerative diseases, including Alzheimer's disease (AD), the exp
Autor:
Robert, Lesurf, Abdelrahman, Said, Oyediran, Akinrinade, Jeroen, Breckpot, Kathleen, Delfosse, Ting, Liu, Roderick, Yao, Gabrielle, Persad, Fintan, McKenna, Ramil R, Noche, Winona, Oliveros, Kaia, Mattioli, Shreya, Shah, Anastasia, Miron, Qian, Yang, Guoliang, Meng, Michelle Chan Seng, Yue, Wilson W L, Sung, Bhooma, Thiruvahindrapuram, Jane, Lougheed, Erwin, Oechslin, Tapas, Mondal, Lynn, Bergin, John, Smythe, Shashank, Jayappa, Vinay J, Rao, Jayaprakash, Shenthar, Perundurai S, Dhandapany, Christopher, Semsarian, Robert G, Weintraub, Richard D, Bagnall, Jodie, Ingles, Marta, Melé, Philipp G, Maass, James, Ellis, Stephen W, Scherer, M, Zarowiecki
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
Cardiomyopathy (CMP) is a heritable disorder. Over 50% of cases are gene-elusive on clinical gene panel testing. The contribution of variants in non-coding DNA elements that result in cryptic splicing and regulate gene expression has not been explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c17280981c333134a3fa06d7ec9729
https://hdl.handle.net/2117/364726
https://hdl.handle.net/2117/364726
Autor:
Vinay J. Rao, Ramachandran Boopathi, Dhanasekan Karthigeyan, Hiroki Shima, Tapas K. Kundu, Arun Kumar Trivedi, Reshma Taneja, Narendra Bharathy, Kazuhiko Igarashi, Arnab Bose
Publikováno v:
The Journal of Biochemistry. 167:195-201
Aurora kinases are Ser/Thr-directed protein kinases which play pivotal roles in mitosis. Recent evidences highlight the importance of these kinases in multiple biological events including skeletal muscle differentiation. Our earlier study identified
Autor:
Muthu K. Shanmugam, K. S. Gopinath, Tapas K. Kundu, Gautam Sethi, Akshay Bhat, Manoj Kumar, Amit K. Behera, Anupam Chatterjee, Madavan Vasudevan, Azeem Mohiyuddin, Aditya Bhattacharya, Vinay J. Rao
Publikováno v:
Oncotarget
Coactivator associated arginine methyltransferase 1 (CARM1) has been functionally implicated in maintenance of pluripotency, cellular differentiation and tumorigenesis; where it plays regulatory roles by virtue of its ability to coactivate transcript
Autor:
Vinay J. Rao, Tapas K. Kundu, Arun Kumar Trivedi, Surabhi Sudevan, Kazuhiko Igarashi, Arnab Bose, Hiroki Shima
Publikováno v:
Journal of Biosciences. 44
The Aurora kinases represent a group of serine/threonine kinases which are crucial regulators of mitosis. Dysregulated Aurora kinase B (AurkB) expression, stemming from genomic amplification, increased gene transcription or overexpression of its allo
The Aurora kinases represent a group of serine/threonine kinases which are crucial regulators of mitosis. Dysregulated Aurora kinase B (AurkB) expression, stemming from genomic amplification, increased gene transcription or overexpression of its allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c7dfa01c241be609629ed96c9818eb
Autor:
Tapas K. Kundu, Dhanasekaran Karthigeyan, Reshma Taneja, Narendra Bharathy, Kazuhiko Igarashi, Arnab Bose, Vinay J. Rao, Ramachandran Boopathi, Hiroki Shima
Aurora kinases are Ser/Thr-directed protein kinases which play pivotal roles in mitosis. Recent evidences highlight the importance of these kinases in non-mitotic biological events like skeletal myogenesis. Our earlier study identified POU6F1 (or mPO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76eda6ff0537ca8cb0c4e58fe10d7cf6