Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vinal Menon"'
Autor:
Zhou Jiang, Juan Wang, Denise Imai, Tim Snider, Jenna Klug, Ruby Mangalindan, John Morton, Lida Zhu, Adam B. Salmon, Jackson Wezeman, Jiayi Hu, Vinal Menon, Nicholas Marka, Laura Neidernhofer, Warren Ladiges
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs targeting different but overlapping processes. In order to determine if combining drugs shown to extend lifespan
Externí odkaz:
https://doaj.org/article/db55d8a2d1a2428eac1def333721ab8d
Autor:
Vinal Menon, Joy Lincoln
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Heart valves are dynamic, highly organized structures required for unidirectional blood flow through the heart. Over an average lifetime, the valve leaflets or cusps open and close over a billion times, however in over 5 million Americans, leaflet fu
Externí odkaz:
https://doaj.org/article/eb2be260be6d44438e126a9dfbf6ac6c
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 2, Iss 2, Pp 108-124 (2015)
Cardiac valve structure and function are primarily determined during early development. Consequently, abnormally-formed heart valves are the most common type of congenital heart defects. Several adult valve diseases can be backtracked to abnormal val
Externí odkaz:
https://doaj.org/article/ee4aa36a67b741e491c8da2c98a393da
Autor:
Sarah Noureddine, Jia Nie, Augusto Schneider, Vinal Menon, Zoubeida Fliesen, Joseph Dhahbi, Berta Victoria, Jeremiah Oyer, Liza Robles-Carrillo, Allancer Divino De Carvalho Nunes, Sarah Ashiqueali, Artur Janusz, Alicja Copik, Paul D. Robbins, Nicolas Musi, Michal M. Masternak
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Cellular senescence, a hallmark of aging, has been implicated in the pathogenesis of many major age-related disorders, including neurodegeneration, atherosclerosis, and metabolic disease. Therefore, investigating novel methods to reduce or delay the
Autor:
Joy Lincoln, Julie R. Kessler, Samuel A. DeCero, Theresa Bluemn, Punashi Dutta, Kaitlyn Thatcher, Donna Mahnke, Makenna Knas, Hail B. Kazik, Vinal Menon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07f6ba6a5af9a097ddfec79796febc61
https://doi.org/10.2139/ssrn.4360592
https://doi.org/10.2139/ssrn.4360592
Autor:
Christopher S. Morrow, Darcie L. Moore, Chung-Yang Yeh, Korbyn Dahlquist, Matthew J. Yousefzadeh, John M. Denu, Michaela E Murphy, Chathurika Henpita, Tadataka Tsuji, Reji Babygirija, Josef P. Clark, Yagna P. R. Jarajapu, Timothy W. Rhoads, Alexis Adrian, Heidi H. Pak, Claire E Richardson, Mariah Calubag, Cara L Green, Cristal M. Hill, Rong Yuan, Ankur Kumar, Michelle Sonsalla, Kishore Chittimalli, Christina D. Camell, Vinal Menon, Mark Bouska, Heather A. Simmons, Yun Zhu, Kyoo-A Lee, Dudley W. Lamming, Eric R McGregor, Hua Bai, Judith Simcox, Carolina Soto-Palma, Akilavalli Narasimhan
Publikováno v:
GeroScience
Autor:
Zhou Jiang, Juan Wang, Denise Imai, Tim Snider, Jenna Klug, Ruby Mangalindan, John Morton, Lida Zhu, Adam B. Salmon, Jackson Wezeman, Jiayi Hu, Vinal Menon, Nicholas Marka, Laura Neidernhofer, Warren Ladiges
Publikováno v:
Scientific reports. 12(1)
Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs targeting different but overlapping processes. In order to determine if combining drugs shown to extend lifespan and heal
Autor:
Timothy A. Snider, Zhou Jiang, Laura Neidernhofer, Juan Wang, Jiayi Hu, Jenna Klug, John Morton, Jackson Wezeman, Lida Zhu, Ruby Mangalindan, Denise M. Imai, Vinal Menon, Warren C. Ladiges, Adam B. Salmon, Nicholas Marka
Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs each targeting different but overlapping processes. In order to determine if combining drugs previously shown to improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42371f9e4673832b8f23ea018ea55fc
https://doi.org/10.1101/2021.10.21.465380
https://doi.org/10.1101/2021.10.21.465380
Autor:
Donald J. DiPette, Michael W. Jenkins, Jay D. Potts, Marwa Belhaj, Alexander J. Potts, Lorain Junor, Vinal Menon, John F. Eberth
Publikováno v:
Developmental Dynamics. 247:531-541
BACKGROUND The formation of healthy heart valves throughout embryonic development is dependent on both genetic and epigenetic factors. Hemodynamic stimuli are important epigenetic regulators of valvulogenesis, but the resultant molecular pathways tha
Autor:
Joy Lincoln, Vinal Menon
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Heart valves are dynamic, highly organized structures required for unidirectional blood flow through the heart. Over an average lifetime, the valve leaflets or cusps open and close over a billion times, however in over 5 million Americans, leaflet fu