Zobrazeno 1 - 2
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pro vyhledávání: '"Vimesh Akotia"'
Autor:
Gary K. Iwamoto, Neil Hoa, Vimesh Akotia, Hamid M. Said, Ali Pedram, Thomas Y. Ma, Michel Boivin
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 286(3)
Crohn's disease (CD) patients have an abnormal increase in intestinal epithelial permeability. The defect in intestinal tight junction (TJ) barrier has been proposed as an important etiologic factor of CD. TNF-alpha increases intestinal TJ permeabili
Publikováno v:
Life sciences. 70(25)
Clinical studies indicate that specific cyclooxygenase-2 (Cox-2) inhibitors are less ulcerogenic than their non-selective predecessors (e.g. indomethacin). However, Cox-2 inhibitors may also interfere with ulcer healing. Re-epithelialization is a cru