Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Vilma Lauris"'
Autor:
Aldo A. Rossini, William Chick, Vilma Lauris, Lydia J. Villa-Komaroff, Stephen Naber, Stephanie A. Broome
Publikováno v:
Gene. 21:95-104
Fused proteins possessing insulin antigenic determinants are synthesized and secreted by several strains of Escherichia coli K-12 bearing plasmids containing cDNA copies of rat proinsulin mRNA. Small amounts of the secreted, fused protein from E. col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949257a2f9f5ee47991b750bb8c93a60
https://doi.org/10.1016/0378-1119(83)90151-8
https://doi.org/10.1016/0378-1119(83)90151-8
Autor:
Janis G. Porter, Michael C. Appel, Arthur A. Like, Vilma Lauris, Rosanna N. Chute, William L. Chick, Gordon C. Weir
Publikováno v:
Endocrinology. 107:954-960
A serially transplantable, chemically induced pancreatic islet cell tumor was developed in Lewis rats. The original tumor was induced by the administration of streptozotocin and nicotinamide. It was subsequently maintained by ip or sc transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3571d9d9bb1be27a515ad1ce3e7a947
https://doi.org/10.1210/endo-107-4-954
https://doi.org/10.1210/endo-107-4-954
Publikováno v:
Endocrinology. 96:637-643
Procedures were developed for preparing partially purified beta cell monolayer cultures. Neonatal rat pancreases were dissociated with a trypsin-collagenase solution. Beta cells were separated from denser acinar cells by centrifuging the initial susp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f6938abc098424ae095f24ae0644ed
https://doi.org/10.1210/endo-96-3-637
https://doi.org/10.1210/endo-96-3-637
Autor:
Shields Warren, William L. Chick, Arthur A. Like, Vilma Lauris, Kyle C. Kitchen, Rosanna N. Chute
Publikováno v:
Proceedings of the National Academy of Sciences. 74:628-632
A transplantable insulinoma was developed in inbred albino rats of the NEDH strain. The original tumor, 1 cm in diameter, was removed from the pancreas of a male parabiont 566 days folowing 1000 rads (10J/kg) of total body x-irradiation. The time req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b311ca4cc18e71676a995d30ce63d93
https://doi.org/10.1073/pnas.74.2.628
https://doi.org/10.1073/pnas.74.2.628
Autor:
George F. Cahill, Vilma Lauris
Publikováno v:
Diabetes. 15:475-479
Glucokinase activity (ATP :D-glucose-6-phosphotransferase, E.C. 2.7.1.2) was assayed in various species, including man ( Homo sapiens ). Low or absent activities were found in the toadfish ( Opsanus tau) cat (Felis domesticus ), guinea pig ( Cavia po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd4af89ab23e5d7588e24efc1c4d2ec
https://doi.org/10.2337/diab.15.7.475
https://doi.org/10.2337/diab.15.7.475
Publikováno v:
Endocrinology. 92:212-218
Monolayer cultures were prepared by dissociating pancreases from newborn rats with a trypsin—collagenase solution. Cultures consisted of numerous discrete colonies containing beta cells, with a network of fibroblastoid cells between colonies. Large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf8eed67b63dab79c265941c1a6952c
https://doi.org/10.1210/endo-92-1-212
https://doi.org/10.1210/endo-92-1-212
Publikováno v:
Metabolism. 13:769-774
Sera from 4 normal subjects were analyzed for insulin and insulin-like activity by immunoassay, adipose tissue bioassay and a combined in vivo bioassay using C14 glucose incorporation into muscle and adipose tissue glycogen and adipose tissue fatty a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e635b49c2eef72cfa8543a9125c52ee5
https://doi.org/10.1016/0026-0495(64)90022-8
https://doi.org/10.1016/0026-0495(64)90022-8
Publikováno v:
Endocrinology. 118(6)
The growth-promoting effect of insulin on cells in culture is well established. In addition, most cells need glucose for growth, although hepatic cells, which have an active gluconeogenic pathway, can survive in glucose-free medium. Since insulin can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc3d0082a8ecd447116cf57fd9fc716
https://pubmed.ncbi.nlm.nih.gov/3516664
https://pubmed.ncbi.nlm.nih.gov/3516664
Autor:
Gordon C. Weir, Adi F. Gazdar, Herbert K. Oie, Harvie L. Sims, Dennis L. King, Vilma Lauris, William L. Chick
Continuous cell lines that secrete both insulin and somatostatin were established by two cooperating groups of investiagtors from a serially transplantable, radiation-induced, rat islet cell tumor. The cell lines, named RIN-r and RIN-m, were initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a1092067aeabc1b4ddcaa52eeefeaf
https://europepmc.org/articles/PMC349648/
https://europepmc.org/articles/PMC349648/
Autor:
M. J. Lysaght, Clark K. Colton, David W. Low, William L. Chick, Vilma Lauris, Arthur A. Like, Pierre M. Galletti, G. Panol, Anthony D. Whittemore, John J. Perna
Publikováno v:
Science (New York, N.Y.). 197(4305)
An artificial pancreas consisting of beta cells cultured on synthetic semipermeable hollow fibers was tested in rats with alloxan-induced diabetes. When implanted ex vivo as arteriovenous shunts in the circulatory system these devices lowered concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798f7f9815c536a9ec42087fedae7087
https://pubmed.ncbi.nlm.nih.gov/407649
https://pubmed.ncbi.nlm.nih.gov/407649