An miRNA-mRNA integrative analysis in human placentas and mice: role of the Smad2/miR-155-5p axis in the development of fetal growth restriction

Autor: Jia-Xing Wu, Ming Shi, Bao-Ming Gong, Bao-Wei Ji, Cheng-Chen Hu, Gui-Cheng Wang, Lei Lei, Chao Tang, Ling V. Sun, Xiao-Hui Wu, Xue Wang

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Introduction: Functional disorder of the placenta is the principal cause of fetal growth restriction (FGR), usually cured with suitable clinical treatment and good nursing. However, some FGR mothers still give birth to small for gestational age (SGA)

Externí odkaz: https://doaj.org/article/2c5aef002d0b43bfabe48db6193a2bcd

Heme Oxygenase-1 Induction in Human BeWo Trophoblast Cells Decreases Toxoplasma gondii Proliferation in Association With the Upregulation of p38 MAPK Phosphorylation and IL-6 Production

Autor: Marcos Paulo Oliveira Almeida, Caroline Martins Mota, Tiago Wilson Patriarca Mineo, Eloisa Amália Vieira Ferro, Bellisa Freitas Barbosa, Neide Maria Silva

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

Heme oxygenase-1 (HO-1) enzyme exerts beneficial effects at the maternal-fetal interface, especially in trophoblasts, being involved in survival and maturation of these cell phenotypes. Trophoblast cells play essential roles throughout pregnancy, bei

Externí odkaz: https://doaj.org/article/30aee45216124548ba156009c7ea82ee

Definition and Quantification of Three-Dimensional Imaging Targets to Phenotype Pre-Eclampsia Subtypes: An Exploratory Study

Autor: Sammy Hermans, Jacob Pilon, Dennis Eschweiler, Johannes Stegmaier, Carmen A. H. Severens–Rijvers, Salwan Al-Nasiry, Marc van Zandvoort, Dimitrios Kapsokalyvas

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3240
International Journal of Molecular Sciences, 24(4):3240. Multidisciplinary Digital Publishing Institute (MDPI)

Pre-eclampsia is a severe placenta-related complication of pregnancy with limited early diagnostic and therapeutic options. Aetiological knowledge is controversial, and there is no universal consensus on what constitutes the early and late phenotypes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50732853885ecaa9fcb16f823d09ba9d

New Insights Into the Role of Placental Aquaporins and the Pathogenesis of Preeclampsia

Autor: Natalia Szpilbarg, Nora A. Martínez, Mauricio Di Paola, Julieta Reppetti, Yollyseth Medina, Abril Seyahian, Mauricio Castro Parodi, Alicia E. Damiano

Publikováno v: Frontiers in Physiology, Vol 9 (2018)

Accumulated evidence suggests that an abnormal placentation and an altered expression of a variety of trophoblast transporters are associated to preeclampsia. In this regard, an abnormal expression of AQP3 and AQP9 was reported in these placentas. Re

Externí odkaz: https://doaj.org/article/f54fa9f4967f45faa021b4c6c4239ff2

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