Zobrazeno 1 - 10 of 1 010 pro vyhledávání: '"Villetti G."'
1
Akademický článek
Quantitative micro-CT-derived biomarkers elucidate age-related lung fibrosis in elder mice.
Autor: Buseghin D; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy.; ANTHEM (AdvaNced Technologies for Human-centrEd Medicine), Spoke 3, Milan, Italy., Grandi A; Experimental Pharmacology & Translational Science Department, Chiesi Farmaceutici S.P.A, Parma, Italy., Ferrini E; ANTHEM (AdvaNced Technologies for Human-centrEd Medicine), Spoke 3, Milan, Italy.; Experimental Pharmacology & Translational Science Department, Chiesi Farmaceutici S.P.A, Parma, Italy., Villetti G; Experimental Pharmacology & Translational Science Department, Chiesi Farmaceutici S.P.A, Parma, Italy., Ciccimarra R; Department of Veterinary Science, University of Parma, Parma, Italy., Sverzellati N; Department of Medicine and Surgery, University of Parma, Parma, Italy., Aliverti A; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy., Pennati F; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy. francesca.pennati@polimi.it., Stellari FF; Experimental Pharmacology & Translational Science Department, Chiesi Farmaceutici S.P.A, Parma, Italy. fb.stellari@chiesi.com.
Publikováno v: Respiratory research [Respir Res] 2024 Oct 30; Vol. 25 (1), pp. 393. Date of Electronic Publication: 2024 Oct 30.
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2
Akademický článek
Quantitative lung ultrasound findings correlate with radial alveolar count in experimental bronchopulmonary dysplasia.
Autor: Catozzi C; Neonatology and Pulmonary Rare Disease Unit, Experimental Pharmacology and Translational Science Department Corporate Preclinical R&D, Chiesi Farmaceutici, Parma, Italy., Modena A; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy., Storti M; Neonatology and Pulmonary Rare Disease Unit, Experimental Pharmacology and Translational Science Department Corporate Preclinical R&D, Chiesi Farmaceutici, Parma, Italy., Ricci F; Neonatology and Pulmonary Rare Disease Unit, Experimental Pharmacology and Translational Science Department Corporate Preclinical R&D, Chiesi Farmaceutici, Parma, Italy., Villetti G; Neonatology and Pulmonary Rare Disease Unit, Experimental Pharmacology and Translational Science Department Corporate Preclinical R&D, Chiesi Farmaceutici, Parma, Italy., De Luca D; Division of Pediatrics and Neonatal Critical Care, 'A. Beclere' Medical Centre, Paris Saclay University Hospitals, APHP, Paris, France. dm.deluca@icloud.com.; Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France. dm.deluca@icloud.com.
Publikováno v: The ultrasound journal [Ultrasound J] 2024 Oct 28; Vol. 16 (1), pp. 46. Date of Electronic Publication: 2024 Oct 28.
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3
Corrigendum: CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.
Autor: Martucci C; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Allen AD; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Moretto N; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Bagnacani V; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Fioni A; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Patacchini R; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Civelli M; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Villetti G; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Facchinetti F; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy.
Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Oct 25; Vol. 15, pp. 1497520. Date of Electronic Publication: 2024 Oct 25 (Print Publication: 2024).
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4
Akademický článek
A p75 neurotrophin receptor-sparing nerve growth factor protects retinal ganglion cells from neurodegeneration by targeting microglia.
Autor: Latini L; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy., De Araujo DSM; Department of Health Sciences, Clinical Pharmacology and Oncology Section, University of Florence, Florence, Italy., Amato R; Department of Biology, University of Pisa, Pisa, Italy., Canovai A; Department of Biology, University of Pisa, Pisa, Italy., Buccarello L; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy., De Logu F; Department of Health Sciences, Clinical Pharmacology and Oncology Section, University of Florence, Florence, Italy., Novelli E; Institute of Neuroscience, Italian National Research Council-CNR, Pisa, Italy., Vlasiuk A; Faculty of Biosciences, Collaboration for Joint PhD Degree Between EMBL and Heidelberg University, Heidelberg, Germany.; Epigenetics and Neurobiology Unit, EMBL Rome, European Molecular Biology Laboratory, Rome, Italy., Malerba F; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy., Arisi I; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy., Florio R; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy., Asari H; Faculty of Biosciences, Collaboration for Joint PhD Degree Between EMBL and Heidelberg University, Heidelberg, Germany., Capsoni S; BIO@SNS Laboratory, Scuola Normale Superiore, Pisa, Italy.; Section of Human Physiology, Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy., Strettoi E; Institute of Neuroscience, Italian National Research Council-CNR, Pisa, Italy., Villetti G; Department of Research & Development, Chiesi Farmaceutici, Parma, Italy., Imbimbo BP; Department of Research & Development, Chiesi Farmaceutici, Parma, Italy., Dal Monte M; Department of Biology, University of Pisa, Pisa, Italy., Nassini R; Department of Health Sciences, Clinical Pharmacology and Oncology Section, University of Florence, Florence, Italy., Geppetti P; Department of Health Sciences, Clinical Pharmacology and Oncology Section, University of Florence, Florence, Italy., Marinelli S; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy., Cattaneo A; European Brain Research Institute-Fondazione Rita Levi-Montalcini, Rome, Italy.; BIO@SNS Laboratory, Scuola Normale Superiore, Pisa, Italy.
Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Dec; Vol. 181 (23), pp. 4890-4919. Date of Electronic Publication: 2024 Sep 09.
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5
Akademický článek
Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β 2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Autor: Carzaniga L; Medicinal Chemistry and Drug Discovery Technologies Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Linney ID; Medicinal Chemistry Department, Charles River, Chesterford Research Park, Saffron Walden, CB10 1XL, Essex United Kingdom., Rizzi A; Medicinal Chemistry and Drug Discovery Technologies Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Schmidt W; Medicinal Chemistry Department, Charles River, Chesterford Research Park, Saffron Walden, CB10 1XL, Essex United Kingdom., Knight CK; Medicinal Chemistry Department, Charles River, Chesterford Research Park, Saffron Walden, CB10 1XL, Essex United Kingdom., Mileo V; Analytics and Early Formulations Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Amadei F; Analytics and Early Formulations Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Pastore F; Pharmacology Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Miglietta D; Pharmacology Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Cesari N; Pharmacokinetics Biochemistry and Metabolism Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Riccardi B; Pharmacokinetics Biochemistry and Metabolism Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Mazzucato R; Medicinal Chemistry and Drug Discovery Technologies Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Ghidini E; Medicinal Chemistry and Drug Discovery Technologies Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Blackaby WP; Medicinal Chemistry Department, Charles River, Chesterford Research Park, Saffron Walden, CB10 1XL, Essex United Kingdom., Patacchini R; AIR Franchise, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Battipaglia L; Safety and Toxicology Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Villetti G; Pharmacology Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Puccini P; Pharmacokinetics Biochemistry and Metabolism Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Catinella S; Analytics and Early Formulations Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Civelli M; Head of Global Research & Preclinical Development, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy., Rancati F; Medicinal Chemistry and Drug Discovery Technologies Department, Chiesi Farmaceutici S.p.A., Research Center, Largo Belloli 11/a, 43122 Parma, Italy.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Jun 27; Vol. 67 (12), pp. 9816-9841. Date of Electronic Publication: 2024 Jun 10.
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6
Akademický článek
Micro-CT-assisted identification of the optimal time-window for antifibrotic treatment in a bleomycin mouse model of long-lasting pulmonary fibrosis.
Autor: Buccardi M; Department of Mathematical, Physical and Computer Sciences, University of Parma, Parma, Italy.; Experimental Pharmacology and Translational Science Department, Chiesi Farmaceutici S.P.A, 43122, Parma, Italy., Grandi A; Experimental Pharmacology and Translational Science Department, Chiesi Farmaceutici S.P.A, 43122, Parma, Italy., Ferrini E; Experimental Pharmacology and Translational Science Department, Chiesi Farmaceutici S.P.A, 43122, Parma, Italy.; Department of Veterinary Science, University of Parma, Parma, Italy., Buseghin D; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.; ANTHEM (AdvaNced Technologies for Human-centrEd Medicine), Spoke 3, Milan, Italy., Villetti G; Experimental Pharmacology and Translational Science Department, Chiesi Farmaceutici S.P.A, 43122, Parma, Italy., Civelli M; Experimental Pharmacology and Translational Science Department, Chiesi Farmaceutici S.P.A, 43122, Parma, Italy., Sverzellati N; Department of Medicine and Surgery, University of Parma, Parma, Italy., Aliverti A; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy., Pennati F; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy., Stellari FF; Experimental Pharmacology and Translational Science Department, Chiesi Farmaceutici S.P.A, 43122, Parma, Italy. fb.stellari@chiesi.com.
Publikováno v: Scientific reports [Sci Rep] 2024 Jun 26; Vol. 14 (1), pp. 14792. Date of Electronic Publication: 2024 Jun 26.
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7
Akademický článek
A mouse model of progressive lung fibrosis with cutaneous involvement induced by a combination of oropharyngeal and osmotic minipump bleomycin delivery.
Autor: Grandi A; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, Parma, Italy., Ferrini E; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, Parma, Italy.; Department of Veterinary Science, University of Parma, Parma, Italy., Zoboli M; Department of Veterinary Science, University of Parma, Parma, Italy., Buseghin D; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, Parma, Italy.; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.; ANTHEM (AdvaNced Technologies for Human-centrEd Medicine), Milan, Italy., Pennati F; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy., Khalajzeyqami Z; Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy., Ciccimarra R; Department of Veterinary Science, University of Parma, Parma, Italy., Villetti G; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, Parma, Italy., Stellari FF; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, Parma, Italy.
Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 Jun 01; Vol. 326 (6), pp. L736-L753. Date of Electronic Publication: 2024 Apr 23.
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8
Akademický článek
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9
Akademický článek
CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.
Autor: Martucci C; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Allen AD; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Moretto N; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Bagnacani V; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Fioni A; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Patacchini R; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Civelli M; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Villetti G; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Facchinetti F; Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy.
Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Mar 14; Vol. 15, pp. 1343941. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024).
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10
Akademický článek
Multiphase micro-computed tomography reconstructions provide dynamic respiratory function in a mouse lung fibrosis model.
Autor: Pennati F; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy., Belenkov S; PerkinElmer, Inc, Waltham, MA, USA., Buccardi M; Department of Mathematical, Physical and Computer Sciences, University of Parma, Parma, Italy., Ferrini E; Department of Veterinary Science, University of Parma, Parma, Italy., Sverzellati N; Department of Medicine and Surgery, University of Parma, Parma, Italy., Villetti G; Pharmacology and Toxicology Department Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy., Aliverti A; Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, Italy., Stellari FF; Pharmacology and Toxicology Department Corporate Pre-Clinical R&D, Chiesi Farmaceutici S.p.A., Parma, Italy.
Publikováno v: IScience [iScience] 2024 Feb 16; Vol. 27 (3), pp. 109262. Date of Electronic Publication: 2024 Feb 16 (Print Publication: 2024).
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