Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling.

Autor: Ng A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Offensperger F; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Cisneros JA; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Scholes NS; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Malik M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Villanti L; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Rukavina A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Ferrada E; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Hannich JT; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Koren A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Kubicek S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria., Superti-Furga G; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.; Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria., Winter GE; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2023 Dec 15; Vol. 18 (12), pp. 2464-2473. Date of Electronic Publication: 2023 Nov 21.

Breaking Bad Proteins—Discovery Approaches and the Road to Clinic for Degraders.

Autor: Bouvier, Corentin¹ (AUTHOR) corentin.bouvier@lcc-toulouse.fr, Lawrence, Rachel² (AUTHOR) f.cavallo@sygnaturediscovery.com, Cavallo, Francesca² (AUTHOR) a.jordan@sygnaturediscovery.com, Xolalpa, Wendy³ (AUTHOR) wendy.xolalpa@ibt.unam.mx, Jordan, Allan² (AUTHOR), Hjerpe, Roland² (AUTHOR) r.hjerpe@sygnaturediscovery.com, Rodriguez, Manuel S.^1,4,5 (AUTHOR) manuel.rodriguez@lcc-toulouse.fr

Publikováno v: Cells (2073-4409). Apr2024, Vol. 13 Issue 7, p578. 37p.

E-Cigarettes and the Multiple Responsibilities of the FDA.

Autor: Svirsky, Larisa¹, Howard, Dana², Berman, Micah L.³

Publikováno v: American Journal of Bioethics. Oct2022, Vol. 22 Issue 10, p5-14. 10p.

Estimated Public Health Gains From German Smokers Switching to Reduced-Risk Alternatives: Results From Population Health Impact Modelling.

Autor: Rytsar, Romana¹ (AUTHOR) Romana.Rytsar@pmi.com, Djurdjevic, Smilja¹ (AUTHOR), Nussbaum, Alexander K.¹ (AUTHOR), Kaul, Ashok¹ (AUTHOR), Bennewitz, Emanuel¹ (AUTHOR), Lee, Peter N.¹ (AUTHOR), Fry, John S.¹ (AUTHOR)

Publikováno v: Contributions to Tobacco & Nicotine Research. Mar2022, Vol. 31 Issue 1, p35-51. 17p.

[Protein induced proximity and targeted degradations by new degraders: concepts, developments, challenges for clinical applications].

Autor: Reboud-Ravaux M; Sorbonne Université, Institut de Biologie Paris Seine (IBPS), CNRS UMR 8256, Inserm ERL U1164, 7 quai Saint-Bernard, 75252 Paris, France.

Publikováno v: Biologie aujourd'hui [Biol Aujourdhui] 2024; Vol. 218 (1-2), pp. 41-54. Date of Electronic Publication: 2024 Jul 15.