Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Viliam Pavliak"'
Autor:
Ingrid L. Scully, Viliam Pavliak, Yekaterina Timofeyeva, Yongdong Liu, Christine Singer, Annaliesa S. Anderson
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 1, Pp 81-84 (2018)
Staphylococcus aureus produces an antiphagocytic polysaccharide capsule to evade neutrophil-mediated killing. Many vaccines against encapsulated bacterial pathogens require generation of functional anti-capsular antibodies to mediate protection again
Externí odkaz:
https://doaj.org/article/98cb7ea7f294425caa9e2ed3b209d505
Autor:
Fikri Avci, Francesco Berti, Peter Dull, John Hennessey, Viliam Pavliak, A. Krishna Prasad, Willie Vann, Michael Wacker, Olivier Marcq
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic. The lack of fundamental understanding of factors controllin
Externí odkaz:
https://doaj.org/article/64ee4e5fc4dc4467b54c8d4b93621122
Autor:
Danka Pavliakova, Peter C. Giardina, Soraya Moghazeh, Shite Sebastian, Maya Koster, Viliam Pavliak, Andrew McKeen, Roger French, Kathrin U. Jansen, Michael Pride
Publikováno v:
mSphere, Vol 3, Iss 4 (2018)
ABSTRACT A Luminex-based direct immunoassay (dLIA) platform has been developed to replace the standardized pneumococcal enzyme-linked immunosorbent assay platform. The multiplex dLIA simultaneously measures the concentration of serum immunoglobulin G
Externí odkaz:
https://doaj.org/article/dbf3807ed7cc4c2999a7c6d1253b02f6
Autor:
Christine Singer, Yekaterina Timofeyeva, Ingrid L. Scully, Viliam Pavliak, Annaliesa S. Anderson, Yongdong Liu
Publikováno v:
Human Vaccines & Immunotherapeutics
Staphylococcus aureus produces an antiphagocytic polysaccharide capsule to evade neutrophil-mediated killing. Many vaccines against encapsulated bacterial pathogens require generation of functional anti-capsular antibodies to mediate protection again
Autor:
Viliam Pavliak, Willie Vann, Francesco Berti, A. Krishna Prasad, Michael Wacker, Olivier Marcq, Fikri Y. Avci, John Hennessey, Peter Dull
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
mSphere, Vol 4, Iss 5, p e00520-19 (2019)
mSphere
mSphere, Vol 4, Iss 5, p e00520-19 (2019)
mSphere
Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic. The lack of fundamental understanding of factors controlling clinica
Autor:
Kathrin U. Jansen, Viliam Pavliak, Soraya Moghazeh, Andrew McKeen, Shite Sebastian, Peter C. Giardina, Danka Pavliakova, Maya Koster, Michael W. Pride, Roger French
Publikováno v:
mSphere, Vol 3, Iss 4 (2018)
mSphere
mSphere, Vol 3, Iss 4, p e00128-18 (2018)
mSphere
mSphere, Vol 3, Iss 4, p e00128-18 (2018)
The pneumococcal enzyme-linked immunosorbent assay (ELISA) measures IgG antibodies in human serum, and it is an important assay that supports licensure of pneumococcal vaccines. The immune correlate of protection, 0.35 µg/ml of IgG antibodies, was d
Autor:
Kathrin U. Jansen, Fiona L. Lin, Evgeny Vinogradov, Viliam Pavliak, Sandra Zeller, Bruce A. Green, Chenghua Deng
Publikováno v:
Carbohydrate Research. 380:101-107
In order to better understand cross-reactions of serogroup 33 polysaccharides and the typing sera, the structure of pneumococcal capsular polysaccharide serotype 33A was elucidated. Serotype 33A has been shown to have an identical polysaccharide back
Autor:
Mark Edward Ruppen, Ping Cai, Viliam Pavliak, Justin Keith Moran, Nancy Khoury, Olivier Marcq, Chenghua Deng
Publikováno v:
Carbohydrate Research. 351:98-107
The original structure of Streptococcus pneumoniae capsular polysaccharide (CPS) serotype 6C was proposed based on chemical degradation and tandem mass analysis [J. Clin. Microbiol.2007, 45, 1225-1233]. In order to confirm the repeat unit structure a
Autor:
Bruce A. Green, Nunez Lorna Del Pilar, Deborah A. Dilts, Sandra M. Buitrago, Yury V. Matsuka, Jasdeep Singh Nanra, Bret R. Sellman, Kathrin U. Jansen, Annaliesa S. Anderson, Viliam Pavliak, Michael Hagen, Pamela S. Fink, Duzhang Zhu, Mininni Terri L, Yekaterina Timofeyeva
Publikováno v:
Vaccine. 27:3276-3280
There is a clear unmet medical need for a vaccine that would prevent infections from Staphylococcus aureus (S. aureus). To validate antigens as potential vaccine targets it has to be demonstrated that the antigens are expressed in vivo. Using murine
Publikováno v:
Carbohydrate Research. 338:2905-2912
The detection of antibodies specific to meningococcal lipo-oligosaccharides (LOSs; outer-core→inner-core→lipid A) in sera of patients convalescent from meningococcal infection suggests the potential use of LOS as a vaccine to combat pathogenic Ne