Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Vilasini Shetty"'
Autor:
Howard M. Kravitz, Azra Raza, Shalini Anthwal, Gurveen Saberwal, Diya Dutt, Poluru L. Reddy, Suneel D. Mundle, Vilasini Shetty, Aaron York, Krishnan Allampallam, Naomi Galili, Maliha Shaikh, Sairah Alvi
Publikováno v:
International Journal of Hematology. 75:289-297
Labeling index (LI), apoptosis, levels of 2 pro-apoptotic cytokines tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta(TGF-beta), and the number of monocyte/macrophage cells that are the likely source of the cytokines were si
Autor:
Naomi Galili, Shalini Anthwal, Sairah Alvi, Diya Dutt, Malihi Shaikh, Vilasini Shetty, Samia Suleman, Poluru L. Reddy, Aaron York, Shaista Y. Kamal, Suneel D. Mundle, Azra Raza, Saleem Dar, Gurveen Saberwal, Krishnan Allampallam
Publikováno v:
British Journal of Haematology. 116:564-575
Mitochondria (mt) play an important role in both apoptosis and haem synthesis. The present study was conducted to determine DNA mutations in mitochondrial encoded cytochrome c-oxidase I and II genes. Bone marrow (BM) biopsy and aspirate, peripheral b
Autor:
Vilasini Shetty, Fabiana Nascimben, Poluru L. Reddy, Azra Raza, Leena Joshi, Naomi Galili, Sairah Alvi, Bruce Dangerfield, Krishnan Allampallam, Ahmed Shaher, Seema Hussaini, Suneel D. Mundle
Publikováno v:
British Journal of Haematology. 116:817-825
Transmission electron microscopic (TEM) studies have not been reported in bone marrow (BM) biopsies of patients with myelodysplastic syndromes (MDS) owing to failure to overcome the technical impediment of maintaining ultrastructural detail in decalc
Autor:
Diya Dutt, Vilasini Shetty, Laurie Lisak, Fabiana Nascimben, Saleem Dar, Krishnan Allampallam, Azra Raza, Francesca Zorat, Parameswaran Venugopal, Sefer Gezer, Aaron York
Publikováno v:
British Journal of Haematology. 115:881-894
Thirty patients with myelodysplastic syndromes (MDS) were treated with thalidomide at 100 mg/d p.o., increased as tolerated to 400 mg/d for 12 weeks. Levels of apoptosis, macrophage number, microvessel density (MVD), tumour necrosis factor alpha (TNF
Autor:
Laurie Lisak, Suneel D. Mundle, Xiao-Ke Huang, Azra Raza, R. Z. Borok, Leena Joshi, Krishnan Allampallam, Bruce Dangerfield, Shalini Anthwal, Poluru L. Reddy, Ahmed Shaher, Sefer Gezer, Francesca Zorat, Leslie Little, Sairah Alvi, Naomi Galili, Benita Henderson, Vilasini Shetty
Publikováno v:
Leukemia Research. 25:941-954
We used bone marrow biopsies instead of mononuclear cells to maintain long-term cultures from 103 patients belonging to all five sub-categories of myelodysplastic syndromes (MDS), as well as 12 normal controls. By week 4, 30-50% confluency was reache
Autor:
Azra Raza, Parameswaran Venugopal, Sairah Alvi, Krishnan Allampallam, Khwaja Aftab Rashid, Bruce Dangerfield, Daniel Zeitler, Evans K. Afenya, Suneel D. Mundle, Jonathan D. Cartlidge, Vilasini Shetty
Publikováno v:
Cancer Letters. 164:197-205
The bone marrow (BM) in myelodysplastic syndromes (MDS) undergoes pathobiological changes that mimic an inflammatory process, and hence, an infectious etiology was suspected in these disorders. In the present report, we examined the bone marrow monon
Autor:
Azra Raza, Eileen Broderick, Vilasini Shetty, Seema Hussaini, Francesca Zorat, Krishnan Allampallam, R. Z. Borok, Lucia Mazzoran, L. Broady-Robinson, Suneel D. Mundle
Publikováno v:
Blood. 96:1388-1392
A higher percentage of apoptotic cells (apoptotic index or AI) is consistently found in bone marrow (BM) biopsies compared to BM aspirates of patients with myelodysplastic syndrome (MDS). Most studies have only investigated the low-density fraction (
Autor:
Stephanie A. Gregory, La Tanya Broady-Robinson, Azra Raza, Bruce Dangerfield, B. Yifwayimare Mativi, Parameswaran Venugopal, Harvey D. Preisler, Suneel D. Mundle, Biarou Li, Jonathan D. Cartlidge, Vilasini Shetty
Publikováno v:
British Journal of Haematology. 109:376-381
Myelodysplastic syndromes (MDS) have previously been reported to show competitively high rates of apoptosis and proliferation in the bone marrow (BM). Using a double-labelling technique in the present study, we demonstrated that a significantly high
Autor:
Ambereen Ali, Saleem Dar, Azra Raza, Samina Reza, Suneel D. Mundle, Deborah Ragasa, Jonathan D. Cartlidge, B. Yifwayimare Mativi, Huma Qawi, Vilasini Shetty, Mohammed Azharuddin
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 8:343-356
Myelodysplastic syndromes (MDS) are a group of hematopoietic disorders characterized by the concomitant presence of peripheral cytopenias and normocellular to hypercellular BM. This paradox has been proposed to be due to the presence of excessive pro
Autor:
Azra Raza, Samina Reza, P. Venugopal, Ambereen Ali, Stephanie A. Gregory, Vilasini Shetty, B. Yifwayimare Mativi, Suneel D. Mundle
Publikováno v:
Cancer Letters. 140:201-207
Increased intramedullary apoptotic death of hematopoietic cells is thought to contribute to the ineffective hematopoiesis in myelodysplastic syndromes (MDS). Furthermore, high amounts of tumor necrosis factor alpha (TNF alpha) have previously been co