Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Vilas Wagh"'
Publikováno v:
ESC Heart Failure, Vol 10, Iss 6, Pp 3559-3572 (2023)
Abstract Aims Mechanochemical signalling drives organogenesis and is highly conserved in mammal evolution. Regaining recovery in myocardial jeopardy by inducing principles linking cardiovascular therapy and clinical outcome has been the dream of scie
Externí odkaz:
https://doaj.org/article/4c623f29ec1b47c1ae5701794d8165c1
Autor:
Pauline Martin, Vilas Wagh, Surya A. Reis, Serkan Erdin, Roberta L. Beauchamp, Ghalib Shaikh, Michael Talkowski, Elizabeth Thiele, Steven D. Sheridan, Stephen J. Haggarty, Vijaya Ramesh
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder with frequent occurrence of epilepsy, autism spectrum disorder (ASD), intellectual disability (ID), and tumors in multiple organs. The aberrant activation of mTORC1
Externí odkaz:
https://doaj.org/article/dacfeeaa9c15418ea8850ec47e4871cc
Autor:
Yang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, M. Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jesse M. Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G. Doench, J. Michael Edwardson, Justin J. Rochford, Evan D. Rosen, Amit R. Majithia
Publikováno v:
Molecular Metabolism, Vol 24, Iss , Pp 108-119 (2019)
Objective: Impaired expansion of peripheral fat contributes to the pathogenesis of insulin resistance and Type 2 Diabetes (T2D). We aimed to identify novel disease–gene interactions during adipocyte differentiation. Methods: Genes in disease-associ
Externí odkaz:
https://doaj.org/article/3a9d99e0cb264ba4a908d1ccdfe713f0
Autor:
Davood Sabour, Sureshkumar Perumal Srinivasan, Susan Rohani, Vilas Wagh, John Antonydas Gaspar, Darius Panek, Mostafa Abootorabi Ardestani, Michael Xavier Doss, Nicole Riet, Hinrich Abken, Jürgen Hescheler, Symeon Papadopoulos, Agapios Sachinidis
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 116-129 (2017)
The role of striatin interacting protein 2 (Strip2) in differentiation of embryonic stem cells (ESCs) is still under debate. Strip2-silenced murine (KD) ESCs were differentiated for 4, 8, 12, and 16 days. We show that Strip2 is distributed in the per
Externí odkaz:
https://doaj.org/article/da8e2ffd82734f58befba7b1bec0940e
Autor:
Lin Li, Ryan M Walsh, Vilas Wagh, Marianne F James, Roberta L Beauchamp, Yuh-Shin Chang, James F Gusella, Konrad Hochedlinger, Vijaya Ramesh
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140192 (2015)
The multi-subunit mammalian Mediator complex acts as an integrator of transcriptional regulation by RNA Polymerase II, and has emerged as a master coordinator of development and cell fate determination. We previously identified the Mediator subunit,
Externí odkaz:
https://doaj.org/article/bc8bc2bccca745978857e1f41f777bf5
Autor:
Martin Lehmann, Filomain Nguemo, Vilas Wagh, Kurt Pfannkuche, Jürgen Hescheler, Michael Reppel
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70913 (2013)
Catecholamine release is known to modulate cardiac output by increasing heart rate. Although much is known about catecholamine function and regulation in adults, little is known about the presence and role of catecholamines during heart development.
Externí odkaz:
https://doaj.org/article/599b24ccd6d142b1be5494b9046e008b
Autor:
Kesavan Meganathan, Smita Jagtap, Vilas Wagh, Johannes Winkler, John Antonydas Gaspar, Diana Hildebrand, Maria Trusch, Karola Lehmann, Jürgen Hescheler, Hartmut Schlüter, Agapios Sachinidis
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44228 (2012)
Embryonic development can be partially recapitulated in vitro by differentiating human embryonic stem cells (hESCs). Thalidomide is a developmental toxicant in vivo and acts in a species-dependent manner. Besides its therapeutic value, thalidomide al
Externí odkaz:
https://doaj.org/article/6b00c48684334bb5a81076f377afc156
Autor:
Vipul Vilas Wagh, Suchita Agrawal, Shruti Purohit, Tejaswini Pachpor, Leelavati Narlikar, Vasudeo Paralikar, Satyajeet Khare
The need for molecular biomarkers for schizophrenia has been well recognized. Peripheral blood gene expression profiling and machine learning (ML) tools have recently become popular for biomarker discovery. The stigmatization associated with schizoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d67bf474e3da5e9c434038e5330a7b
https://doi.org/10.1101/2023.02.11.23285788
https://doi.org/10.1101/2023.02.11.23285788
Autor:
Vilas Wagh, Pauline Martin, Ghalib Shaikh, Roberta L. Beauchamp, Steven D. Sheridan, Michael E. Talkowski, Stephen J. Haggarty, Elizabeth A. Thiele, Surya A. Reis, Vijaya Ramesh, Serkan Erdin
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-15 (2020)
Background Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder with frequent occurrence of epilepsy, autism spectrum disorder (ASD), intellectual disability (ID), and tumors in multiple organs. The aberrant activation of mTORC1 in TSC h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e2766ac1a6ec148a4c75666783fb05
https://doaj.org/article/dacfeeaa9c15418ea8850ec47e4871cc
https://doaj.org/article/dacfeeaa9c15418ea8850ec47e4871cc
Autor:
Suchita Agrawal, Vipul Vilas Wagh, Vasudeo Paralikar, Parin Vyas, Tejaswini A Pachpor, Satyajeet P. Khare
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
Schizophrenia is a disorder that is characterized by delusions, hallucinations, disorganized speech or behavior, and socio-occupational impairment. The duration of observation and variability in symptoms can make the accurate diagnosis difficult. Ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3bb7356aac27e974433faacc2fa921
https://www.frontiersin.org/articles/10.3389/fgene.2021.736483/full
https://www.frontiersin.org/articles/10.3389/fgene.2021.736483/full