Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vilas K. Shah"'
Autor:
Geoffrey Martyn Williams, Felix Spindler, Daniel Black, Philippe Wong-Kai-In, P. John Murray, Martin James Procter, Rosemary Chatfield, Lisa Sarah Bertram, Andrew Cooke, Kosuke Yasuda, Roy Turton, Paul H. Briner, Frédéric Naud, Karen Lesley Schofield, Günaj Rakipovski, Amanda Taylor, Masao Nawano, Christine Reynet, Chrystelle Marie Rasamison, Matthew Colin Thor Fyfe, Vilas K. Shah
Publikováno v:
Journal of Medicinal Chemistry. 51:4340-4345
Allosteric activators of the glucose-sensing enzyme glucokinase (GK) are currently attracting much interest as potential antidiabetic therapies because they can achieve powerful blood glucose lowering through actions in multiple organs. Here, the opt
Autor:
Chrystelle Marie Rasamison, David J. Witter, Satomi Kurabayashi, Kosuke Yasuda, Kiichiro Ueta, Geoffrey Martyn Williams, Vilas K. Shah, Arlindo L. Castelhano, Masao Nawano, Karen Lesley Schofield, Matthew C. T. Fyfe, Rikiya Ohashi, Li Qiu, Martin James Procter, Lisa Sarah Gardner, Hanqing Dong, Yukari Kamikozawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1501-1504
The synthesis, SAR and biological evaluation of a series of ureas that activate glucokinase, a target for diabetes therapy as a result of its critical role in the regulation of whole-body glucose homeostasis, are described. Some of the urea-containin
Autor:
Lisa S. Bertram, Daniel Black, Paul H. Briner, Rosemary Chatfield, Andrew Cooke, P. John Murray, Frédéric Naud, Masao Nawano, Martin J. Procter, Günaj Rakipovski, Chrystelle M. Rasamison, Christine Reynet, Karen L. Schofield, Vilas K. Shah, Felix Spindler, Amanda Taylor, Roy Turton, Geoffrey M. Williams, Philippe Wong-Kai-In, Kosuke Yasuda
Publikováno v:
Journal of Medicinal Chemistry; Jun2008, Vol. 51 Issue 14, p4340-4345, 6p
Autor:
Martin A. Bennett, James P. Ennett, Derek A. Tocher, T. Anthony Stephenson, Vilas K. Shah, Lindsay Sawyer, Robert O. Gould, Trevor W. Matheson
Publikováno v:
J. Chem. Soc., Dalton Trans.. :1571-1581
The preparation of monomeric areneruthenium(II) acetates and trifluoroacetates [Ru(η-arene)X(O2CR)] and [Ru(η-arene)(O2CR)2](X = Cl or Br; R = Me or CF3; arene = C6H6, p-MeC6H4CHMe2, C6H3Me3-1,3,5, C6H2Me4-1,2,4,5, or C6Me6)(not all possible combin