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pro vyhledávání: '"Viktorija Hojzan"'
Autor:
Peter Canning, Christopher D.O. Cooper, Tobias Krojer, James W. Murray, Ashley C.W. Pike, Apirat Chaikuad, Tracy Keates, Chancievan Thangaratnarajah, Viktorija Hojzan, Vikram Ayinampudi, Brian D. Marsden, Opher Gileadi, Stefan Knapp, Frank von Delft, Alex N. Bullock
Publikováno v:
The Journal of Biological Chemistry
Background: BTB-Kelch proteins, including KLHL11, are proposed to bind Cul3 through a “3-box” motif to form E3 ubiquitin ligases. Results: We solved crystal structures of the KLHL11-Cul3 complex and four Kelch domains. Conclusion: The 3-box forms