Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Viktoria S. Babiychuk"'
Publikováno v:
Cells, Vol 11, Iss 1, p 166 (2022)
The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their vir
Externí odkaz:
https://doaj.org/article/1a6c0cf01d9f4eb68bc7fbae3a765c70
Autor:
René Köffel, Heidi Wolfmeier, Yu Larpin, Hervé Besançon, Roman Schoenauer, Viktoria S. Babiychuk, Patrick Drücker, Thomas Pabst, Timothy J. Mitchell, Eduard B. Babiychuk, Annette Draeger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell
Externí odkaz:
https://doaj.org/article/ab204a27906c4eb7b16198098641d220
Autor:
Eduard B. Babiychuk, Heidi Wolfmeier, Lucy J. Hathaway, Viktoria S. Babiychuk, Julika Radecke, Patrick Drücker, Annette Draeger, Timothy J. Mitchell, René Koeffel, Benoît Zuber, Roman Schoenauer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1860:2498-2509
Background Streptococcus pneumoniae is a potent human pathogen. Its pore-forming exotoxin pneumolysin is instrumental for breaching the host's epithelial barrier and for the incapacitation of the immune system. Methods and results Using a combination
Autor:
Roman Schoenauer, Heidi Wolfmeier, Annette Draeger, René Köffel, Viktoria S. Babiychuk, Patrick Drücker, Simon Bachler, Petra S. Dittrich, Eduard B. Babiychuk
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
Nucleated cells eliminate lesions induced by bacterial pore-forming toxins, such as pneumolysin via shedding patches of damaged plasmalemma into the extracellular milieu. Recently, we have shown that the majority of shed pneumolysin is present in the