Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Viktoria Ruf"'
Autor:
Arnt Ebinger, Pauline D. Santos, Florian Pfaff, Ralf Dürrwald, Jolanta Kolodziejek, Kore Schlottau, Viktoria Ruf, Friederike Liesche-Starnecker, Armin Ensser, Klaus Korn, Reiner Ulrich, Jenny Fürstenau, Kaspar Matiasek, Florian Hansmann, Torsten Seuberlich, Daniel Nobach, Matthias Müller, Antonie Neubauer-Juric, Marcel Suchowski, Markus Bauswein, Hans-Helmut Niller, Barbara Schmidt, Dennis Tappe, Daniel Cadar, Timo Homeier-Bachmann, Viola C. Haring, Kirsten Pörtner, Christina Frank, Lars Mundhenk, Bernd Hoffmann, Jochen Herms, Wolfgang Baumgärtner, Norbert Nowotny, Jürgen Schlegel, Rainer G. Ulrich, Martin Beer, Dennis Rubbenstroth
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Croci
Externí odkaz:
https://doaj.org/article/64d16e8c53a642a49924449a6c1d6523
Publikováno v:
Free Neuropathology, Vol 5 (2024)
Background: The postmortem diagnostic of individuals having suffered presumptive neurodegenerative disease comprises exclusion of a prion disease, extensive brain sampling and histopathological evaluation, which are resource-intensive and time consum
Externí odkaz:
https://doaj.org/article/ccfed883cf2541b0ab86c200b079d639
Autor:
Lorraine Weidner, Julia Lorenz, Stefanie Quach, Frank K. Braun, Tanja Rothhammer-Hampl, Laura-Marie Ammer, Arabel Vollmann-Zwerenz, Laura M. Bartos, Franziska J. Dekorsy, Adrien Holzgreve, Sabrina V. Kirchleitner, Niklas Thon, Tobias Greve, Viktoria Ruf, Jochen Herms, Stefanie Bader, Vladimir M. Milenkovic, Louisa von Baumgarten, Ayse N. Menevse, Abir Hussein, Julian Sax, Christian H. Wetzel, Rainer Rupprecht, Martin Proescholdt, Nils O. Schmidt, Philipp Beckhove, Peter Hau, Joerg-Christian Tonn, Peter Bartenstein, Matthias Brendel, Nathalie L. Albert, Markus J. Riemenschneider
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of brain tumors. However, due to the heterogeneity of cell populations that contribute to the TSPO-PET signal, imaging interpretation may be challenging.
Externí odkaz:
https://doaj.org/article/882098c23867491bad20bb37d6a6accc
Autor:
Athanasios Lourbopoulos, Lea Schnurbus, Ricarda Guenther, Susanne Steinlein, Viktoria Ruf, Jochen Herms, Klaus Jahn, Volker Huge
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
BackgroundSince the first report of fatal Borna virus-1 (BoDV-1) encephalitis in 2018, cases gradually increased. There is a lack of diagnostic algorithm, and there is no effective treatment so far.Case presentationWe report an acute BoDV-1 encephali
Externí odkaz:
https://doaj.org/article/97d7fb7abbad4fe2913cf520cb3e893d
Autor:
Yanina Dening, Theresa Straßl, Viktoria Ruf, Petra Dirscherl, Alexandra Chovsepian, Alicia Stievenard, Amit Khairnar, Felix Schmidt, Florian Giesert, Jochen Herms, Johannes Levin, Marianne Dieterich, Peter Falkai, Daniela Vogt Weisenhorn, Wolfgang Wurst, Armin Giese, Francisco Pan-Montojo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Parkinson´s disease (PD) pathology progresses throughout the nervous system. Whereas motor symptoms are always present, there is a high variability in the prevalence of non-motor symptoms. It has been postulated that the progression of the
Externí odkaz:
https://doaj.org/article/df9b737ba1f5425f9e76fb14819c51e7
Autor:
Sebastian Schmidt, Malte D. Luecken, Dietrich Trümbach, Sina Hembach, Kristina M. Niedermeier, Nicole Wenck, Klaus Pflügler, Constantin Stautner, Anika Böttcher, Heiko Lickert, Ciro Ramirez-Suastegui, Ruhel Ahmad, Michael J. Ziller, Julia C. Fitzgerald, Viktoria Ruf, Wilma D. J. van de Berg, Allert J. Jonker, Thomas Gasser, Beate Winner, Jürgen Winkler, Daniela M. Vogt Weisenhorn, Florian Giesert, Fabian J. Theis, Wolfgang Wurst
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-25 (2022)
Here, the authors reveal using single-cell RNA sequencing that Parkinson’s disease (PD) patient-derived neuronal cells show altered primary cilia morphology and signaling suggesting cilia dysfunction may underlie PD pathogenesis.
Externí odkaz:
https://doaj.org/article/b648848b74c14840be9be48f8be10660
Autor:
Tanja Paul, Stephan Ledderose, Harald Bartsch, Na Sun, Sarah Soliman, Bruno Märkl, Viktoria Ruf, Jochen Herms, Marcel Stern, Oliver T. Keppler, Claire Delbridge, Susanna Müller, Guido Piontek, Yuki Schneider Kimoto, Franziska Schreiber, Tracy Ann Williams, Jens Neumann, Thomas Knösel, Heiko Schulz, Ria Spallek, Matthias Graw, Thomas Kirchner, Axel Walch, Martina Rudelius
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Progressive respiratory failure is the primary cause of death in patients with COVID-19, but pathologies in other tissues may also occur. Here the authors report that adrenal tropism of SARS-CoV-2 is associated with adrenalitis, reduced adrenal corti
Externí odkaz:
https://doaj.org/article/7fc103aedd184704955cc35b6504532f
Autor:
Franziska J. Vettermann, Caroline Diekmann, Lorraine Weidner, Marcus Unterrainer, Bogdana Suchorska, Viktoria Ruf, Mario Dorostkar, Vera Wenter, Jochen Herms, Jörg-Christian Tonn, Peter Bartenstein, Markus J. Riemenschneider, Nathalie L. Albert
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Background O-(2-[18F]-fluoroethyl)-L-tyrosine (18F-FET) is a highly sensitive PET tracer for glioma imaging, and its uptake is suggested to be driven by an overexpression of the L-type amino-acid transporter 1 (LAT1). However, 30% of low- an
Externí odkaz:
https://doaj.org/article/a33fc555e32e4212abb9c7249c239995
Autor:
Marcus Unterrainer, Viktoria Ruf, Katharina von Rohr, Bogdana Suchorska, Lena Maria Mittlmeier, Leonie Beyer, Matthias Brendel, Vera Wenter, Wolfgang G. Kunz, Peter Bartenstein, Jochen Herms, Maximilian Niyazi, Jörg C. Tonn, Nathalie Lisa Albert
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveThe mutation of the ‘telomerase reverse transcriptase gene promoter’ (TERTp) has been identified as an important factor for individual prognostication and tumorigenesis and will be implemented in upcoming glioma classifications. Uptake c
Externí odkaz:
https://doaj.org/article/e14ce199347c4824be1992ab5489c475
Autor:
Mahdyeh Sashourpour, Saber Zahri, Tayebeh Radjabian, Viktoria Ruf, Francisco Pan-Montojo, Dina Morshedi
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184483 (2017)
Aggregation of alpha-synuclein (α-SN) is a key pathogenic event in Parkinson's disease (PD) leading to dopaminergic degeneration. The identification of natural compounds inhibiting α-SN aggregation may have a major role in treating PD. Different Sc
Externí odkaz:
https://doaj.org/article/a6bb8703391644fc8631db39117021f4