Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Viktoria Laszlo"'
Autor:
Christian Lang, Zsolt Megyesfalvi, Andras Lantos, Felicitas Oberndorfer, Mir Alireza Hoda, Anna Solta, Bence Ferencz, Janos Fillinger, Anna Solyom-Tisza, Alessandro Saeed Querner, Felix Egger, Kristiina Boettiger, Thomas Klikovits, Gerald Timelthaler, Ferenc Renyi-Vamos, Clemens Aigner, Konrad Hoetzenecker, Viktoria Laszlo, Karin Schelch, Balazs Dome
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the
Externí odkaz:
https://doaj.org/article/234161e89df04bc49487dd2d775855f8
Autor:
Berta Mosleh, Karin Schelch, Thomas Mohr, Thomas Klikovits, Christina Wagner, Lukas Ratzinger, Yawen Dong, Katharina Sinn, Alexander Ries, Walter Berger, Bettina Grasl‐Kraupp, Konrad Hoetzenecker, Viktoria Laszlo, Balazs Dome, Balazs Hegedus, Marko Jakopovic, Mir Alireza Hoda, Michael Grusch
Publikováno v:
Thoracic Cancer, Vol 14, Iss 22, Pp 2177-2186 (2023)
Abstract Background Pleural mesothelioma (PM) is a relatively rare malignancy with limited treatment options and dismal prognosis. We have previously found elevated FGF18 expression in PM tissue specimens compared with normal mesothelium. The objecti
Externí odkaz:
https://doaj.org/article/280b1a46403a482d865fcc37356d2cba
Autor:
Anna Schwendenwein, Zsolt Megyesfalvi, Nandor Barany, Zsuzsanna Valko, Edina Bugyik, Christian Lang, Bence Ferencz, Sandor Paku, Andras Lantos, Janos Fillinger, Melinda Rezeli, Gyorgy Marko-Varga, Krisztina Bogos, Gabriella Galffy, Ferenc Renyi-Vamos, Mir Alireza Hoda, Walter Klepetko, Konrad Hoetzenecker, Viktoria Laszlo, Balazs Dome
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 470-483 (2021)
Small cell lung cancer (SCLC; accounting for approximately 13%–15% of all lung cancers) is an exceptionally lethal malignancy characterized by rapid doubling time and high propensity to metastasize. In contrast to the increasingly personalized ther
Externí odkaz:
https://doaj.org/article/88d8695340f84189ac9c8682d2e28c37
Autor:
Zsolt Megyesfalvi, Bernadett Tallosy, Orsolya Pipek, Janos Fillinger, Christian Lang, Thomas Klikovits, Anna Schwendenwein, Mir Alireza Hoda, Ferenc Renyi‐Vamos, Viktoria Laszlo, Melinda Rezeli, Judit Moldvay, Balazs Dome
Publikováno v:
Thoracic Cancer, Vol 12, Iss 6, Pp 914-923 (2021)
Abstract Background Early metastasis is a hallmark of small cell lung cancer (SCLC). However, the mechanisms and resulting patterns of SCLC dissemination are unclear. Our aim was thus to investigate the organ specificity and timing of blood‐borne m
Externí odkaz:
https://doaj.org/article/7679c7f58f2b4212b339e429249b995f
Autor:
David Dora, Christopher Rivard, Hui Yu, Paul Bunn, Kenichi Suda, Shengxiang Ren, Shivaun Lueke Pickard, Viktoria Laszlo, Tunde Harko, Zsolt Megyesfalvi, Judit Moldvay, Fred R. Hirsch, Balazs Dome, Zoltan Lohinai
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 1947-1965 (2020)
Small cell lung cancer (SCLC) has recently been subcategorized into neuroendocrine (NE)‐high and NE‐low subtypes showing ‘immune desert’ and ‘immune oasis’ phenotypes, respectively. Here, we aimed to characterize the tumor microenvironmen
Externí odkaz:
https://doaj.org/article/472d643d2641458289ff49cabf44a6e0
Autor:
Thomas Aschacher, Brigitte Wolf, Olivia Aschacher, Florian Enzmann, Viktoria Laszlo, Barbara Messner, Adrian Türkcan, Serge Weis, Sabine Spiegl-Kreinecker, Klaus Holzmann, Günther Laufer, Marek Ehrlich, Michael Bergmann
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 61-75 (2020)
Malignant cells ensure telomere maintenance by the alternative lengthening of telomeres (ALT) in the absence of telomerase activity (TA). The retrotransposons “long interspersed nuclear element-1” (LINE-1, L1) are expressed in malignant cells and
Externí odkaz:
https://doaj.org/article/59b8f979431749d7b9261af0ff72292d
Autor:
Olga Kelemen, Indira Pla, Aniel Sanchez, Melinda Rezeli, Attila Marcell Szasz, Johan Malm, Viktoria Laszlo, Ho Jeong Kwon, Balazs Dome, Gyorgy Marko‐Varga
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 2, Pp n/a-n/a (2020)
Abstract Background A gel‐free proteomic approach was utilized to perform in‐depth tissue protein profiling of lung adenocarcinoma (ADC) and normal lung tissues from early and advanced stages of the disease. The long‐term goal of this study is
Externí odkaz:
https://doaj.org/article/14e8ff28a62e44638e7675f8d0cf28df
Autor:
David Dora, Christopher Rivard, Hui Yu, Shivaun Lueke Pickard, Viktoria Laszlo, Tunde Harko, Zsolt Megyesfalvi, Elek Dinya, Csongor Gerdan, Gabor Szegvari, Fred R. Hirsch, Balazs Dome, Zoltan Lohinai
Publikováno v:
Biology, Vol 10, Iss 6, p 502 (2021)
This study aims to characterize tumor-infiltrating macrophages (TAMs), myeloid-derived suppressor cells (MDSC), and the related molecular milieu regulating anti-tumor immunity in limited-stage neuroendocrine (NE)-high and NE-low small cell lung cance
Externí odkaz:
https://doaj.org/article/2cee132fc6194883835e9b27dc5ff42a
Autor:
Maxim Pilyugin, Pascaline Descloux, Pierre-Alain André, Viktoria Laszlo, Balazs Dome, Balazs Hegedus, Sylvain Sardy, Samuel Janes, Andrea Bianco, Geoffrey J Laurent, Irmgard Irminger-Finger
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182356 (2017)
Currently the screening for lung cancer for risk groups is based on Computed Tomography (CT) or low dose CT (LDCT); however, the lung cancer death rate has not decreased significantly with people undergoing LDCT. We aimed to develop a simple reliable
Externí odkaz:
https://doaj.org/article/3c858d221384416286c1a87614ef638d
Autor:
Gregor Vlacic, Mir A. Hoda, Thomas Klikovits, Katharina Sinn, Elisabeth Gschwandtner, Katja Mohorcic, Karin Schelch, Christine Pirker, Barbara Peter-Vörösmarty, Jelena Brankovic, Balazs Dome, Viktoria Laszlo, Tanja Cufer, Ales Rozman, Walter Klepetko, Bettina Grasl-Kraupp, Balazs Hegedus, Walter Berger, Izidor Kern, Michael Grusch
Publikováno v:
Cells, Vol 8, Iss 9, p 1091 (2019)
Malignant pleural mesothelioma (MPM) is a devastating malignancy with limited therapeutic options. Fibroblast growth factor receptors (FGFR) and their ligands were shown to contribute to MPM aggressiveness and it was suggested that subgroups of MPM p
Externí odkaz:
https://doaj.org/article/93a0924cae6848339dc2f41bc3fcc253