Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Viktoras Masevicius"'
Autor:
Milda Mickutė, Renatas Krasauskas, Kotryna Kvederavičiūtė, Gytė Tupikaitė, Aleksandr Osipenko, Algirdas Kaupinis, Monika Jazdauskaitė, Raminta Mineikaitė, Mindaugas Valius, Viktoras Masevičius, Giedrius Vilkaitis
Publikováno v:
mSystems, Vol 8, Iss 5 (2023)
ABSTRACT Both prokaryotic and eukaryotic RNAs can be 5′-capped by the metabolite nicotinamide adenine dinucleotide (NAD). Nudix hydrolases, such as bacterial NudC, specifically remove NAD-caps; however, the molecular and cellular functions of these
Externí odkaz:
https://doaj.org/article/c961c57afb5045acbf12f279c2ce9818
Autor:
Janina Ličytė, Kotryna Kvederavičiūtė, Audronė Rukšėnaitė, Eglė Godliauskaitė, Povilas Gibas, Vita Tomkutė, Gražina Petraitytė, Viktoras Masevičius, Saulius Klimašauskas, Edita Kriukienė
Publikováno v:
Open Biology, Vol 12, Iss 3 (2022)
The formation of three oxidative DNA 5-methylcytosine (5mC) modifications (oxi-mCs)—5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC)—by the TET/JBP family of dioxygenases prompted intensive studies of their fun
Externí odkaz:
https://doaj.org/article/00bdd20eac5c49a998bc78e8fbd49c3d
Autor:
Rasa Rakauskaitė, Giedrė Urbanavičiūtė, Martynas Simanavičius, Rita Lasickienė, Aušra Vaitiekaitė, Gražina Petraitytė, Viktoras Masevičius, Aurelija Žvirblienė, Saulius Klimašauskas
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101833- (2020)
Summary: Photochemical transformations enable exquisite spatiotemporal control over biochemical processes; however, methods for reliable manipulations of biomolecules tagged with biocompatible photo-sensitive reporters are lacking. Here we created a
Externí odkaz:
https://doaj.org/article/830c0ab1bd404b8f8512da1988cc6b0a
Publikováno v:
Tetrahedron Letters. 60:1019-1021
A two-step protocol for the synthesis of 5-substituted or 5,6-disubstituted furo[2,3-d]pyrimidines using bifunctional electrophiles and a pyrimidine derivative was developed. The first step is O-alkylation of 2-methylthiopyrimidin-4,6-dione utilizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1e075769d4e11c73b56e26012281837
https://doi.org/10.1016/j.tetlet.2019.03.017
https://doi.org/10.1016/j.tetlet.2019.03.017
Autor:
Alexandra Plotnikova, Saulius Klimašauskas, Giedrius Vilkaitis, Aleksandr Osipenko, Milda Nainytė, Viktoras Masevicius
Publikováno v:
Angewandte Chemie. 129:6607-6610
The HEN1 RNA 2'-O-methyltransferase plays important roles in the biogenesis of small non-coding RNAs in plants and proved a valuable tool for selective transfer of functional groups from cofactor analogues onto miRNA and siRNA duplexes in vitro. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5119275ca271149b311162e04e58f7e3
https://doi.org/10.1002/ange.201701448
https://doi.org/10.1002/ange.201701448
Autor:
Viktoras Masevicius, Rasa Rakauskaitė, Giedrė Urbanavičiūtė, Saulius Klimašauskas, Gražina Petraitytė, Aušra Vaitiekaitė, Rita Lasickienė, Martynas Simanavicius, Aurelija Žvirblienė
Publikováno v:
iScience
iScience, Cambridge, MA : Cell Press, 2020, vol. 23, iss. 12, art. no. 101833, p. 1-28
iScience, Vol 23, Iss 12, Pp 101833-(2020)
iScience, Cambridge, MA : Cell Press, 2020, vol. 23, iss. 12, art. no. 101833, p. 1-28
iScience, Vol 23, Iss 12, Pp 101833-(2020)
Summary Photochemical transformations enable exquisite spatiotemporal control over biochemical processes; however, methods for reliable manipulations of biomolecules tagged with biocompatible photo-sensitive reporters are lacking. Here we created a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963e8843e3e46f8bcabb8151ac46f439
https://doi.org/10.1016/j.isci.2020.101833
https://doi.org/10.1016/j.isci.2020.101833
Autor:
Milda Nainyte, Viktoras Masevicius
Publikováno v:
Organic Chemistry: Current Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb93ed77497c75ca55f4aae235ea1e01
https://doi.org/10.4172/2161-0401.c1.017
https://doi.org/10.4172/2161-0401.c1.017
Publikováno v:
Synthesis. 45:2438-2446
A new protocol was developed for the synthesis of 2,3-dihydroimidazo[1,2-c]pyrimidines, based on an intramolecular reaction between a pyrimidine nitrogen atom and an acetal moiety in the presence of boron trifluoride etherate. The method was expanded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::940bed369299b70585435de15028e3e6
https://doi.org/10.1055/s-0033-1339350
https://doi.org/10.1055/s-0033-1339350
Publikováno v:
ACS Chemical Biology
Methyltransferases catalyze specific transfers of methyl groups from the ubiquitous cofactor S-adenosyl-l-methionine (AdoMet) to various nucleophilic positions in biopolymers like DNA, RNA, and proteins. We had previously described synthesis and appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338044468a374da40ca93bff8f513a0c
https://doi.org/10.1021/cb300669x
https://doi.org/10.1021/cb300669x
Publikováno v:
Current Protocols in Nucleic Acid Chemistry
S-Adenosyl-L-methionine (AdoMet) is a ubiquitous methyl donor for a variety of biological methylation reactions catalyzed by methyltransferases (MTases). AdoMet analogs with extended propargylic chains replacing the sulfonium-bound methyl group can s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fcb3f37d6bbb4173da67620e93a226
https://europepmc.org/articles/PMC4788031/
https://europepmc.org/articles/PMC4788031/
