Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Viktor Roschke"'
Publikováno v:
Monoclonal Antibodies: Development, Delivery and Applications. :24-38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d452a396546b3d91a3a2101cd32eb2ad
https://doi.org/10.4155/fseb2013.13.62
https://doi.org/10.4155/fseb2013.13.62
Autor:
Ernie Boyd, Rutul R. Shah, Shashi Kaithamana, Geping Wang, Spandana Kankanala, Viktor Roschke, Xiao-Tao Yao, David M. Hilbert, Viktoriya Nam, Rodger Smith, Pete Buasen, Carlos F. Barbas, Liubov Zaritskaya, Peter Kiener, Bridget A. Puffer, Donara Abramyan, Rajesh Krishnamurthy, Palanisamy Kanakaraj, David W. Lafleur, Andrew F. Burnette, Dimki R. Patel
Publikováno v:
mAbs. 5:208-218
The recognition that few human diseases are thoroughly addressed by mono-specific, monoclonal antibodies (mAbs) continues to drive the development of antibody therapeutics with additional specificities and enhanced activity. Historically, efforts to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::852c725fbaa848a5209b6dcc9ac53edf
https://doi.org/10.4161/mabs.23043
https://doi.org/10.4161/mabs.23043
Autor:
Sevil Yasar, Jack Bergman, Doug Woods, Liora Sklair-Tavron, Charles W. Schindler, Steven R. Goldberg, Godfrey H. Redhi, Hussein Hallak, David W. Lafleur, Viktor Roschke, Zuzana Justinova
Publikováno v:
Addiction Biology. 18:30-39
Although substantial research effort has focused on developing pharmacological treatments for cocaine abuse, no effective medications have been developed. Recent studies show that enzymes that metabolize cocaine in the periphery, forestalling its ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc557f1eed1d83769a7ce28326b5055d
https://doi.org/10.1111/j.1369-1600.2011.00424.x
https://doi.org/10.1111/j.1369-1600.2011.00424.x
Autor:
David M. Hilbert, Palanisamy Kanakaraj, Carlos F. Barbas, Peter Kiener, Xiao-Tao Yao, Rodger Smith, Rutul R. Shah, Bridget A. Puffer, David W. Lafleur, Geping Wang, Dimki R. Patel, Ernest Boyd, Shashi Kaithamana, Spandana Kankanala, Viktor Roschke, Rajesh Krishnamurthy
Publikováno v:
mAbs
Despite the clinical success of anti-tumor necrosis factor (TNF) therapies in the treatment of inflammatory conditions such as rheumatoid arthritis, Crohn disease and psoriasis, full control of the diseases only occurs in a subset of patients and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13f095077c2ca2afd17873ce87bd5bd
http://europepmc.org/articles/PMC3499301
http://europepmc.org/articles/PMC3499301
Autor:
Mary Devlin, Daniel J. Sexton, Charles R. Wescott, Robert C. Lander, David M. Hilbert, Viktor Roschke, Meena Sachdeva, Andrew E. Nixon, Marko Delic, James P. Beltzer, Tony J. Fleming
Publikováno v:
Journal of Molecular Recognition. 18:94-102
B lymphocyte stimulator (BLyS) is a tumor necrosis factor (TNF) family member and a key regulator of B cell responses. We employed a phage display-based approach to identify peptides that bind BLyS with high selectivity and affinity. Sequence analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673dac75d1f4d69d4cd59affd327c295
https://doi.org/10.1002/jmr.722
https://doi.org/10.1002/jmr.722
Autor:
Samy Metyas, Gurtej S. Cheema, Viktor Roschke, B Oamar, Y Wu, S-M Tan, William Stohl, David M. Hilbert, Kevin P. Baker
Publikováno v:
Annals of the Rheumatic Diseases. 63:1096-1103
Objective: To assess longitudinal expression of a proliferation-inducing ligand (APRIL) in patients with systemic lupus erythematosus (SLE) and its correlation with B lymphocyte stimulator (BLyS) expression, serum anti-dsDNA titres, and clinical dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e78cc61fed057c5481a5b4a4a20bd2
https://doi.org/10.1136/ard.2003.018663
https://doi.org/10.1136/ard.2003.018663
Autor:
David M. Hilbert, Tristan J. Vaughan, Sarah Helen Main, Bonnie Sturm, Bryan M. Edwards, Vivian R. Albert, Claire Dobson, Les Sekut, Ralph Minter, Wendy Halpern, Carol Poortman, Ruth E. Wager, Todd A. Riccobene, Gil H. Choi, Rodger Smith, Donara Abramian, Kevin P. Baker, Sara Carmen, Patrick B. Lappin, Elizabeth N. Williams, Viktor Roschke
Publikováno v:
Arthritis & Rheumatism. 48:3253-3265
Objective To identify and characterize a fully human antibody directed against B lymphocyte stimulator (BLyS), a tumor necrosis factor–related cytokine that plays a critical role in the regulation of B cell maturation and development. Elevated leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febf038ea97c145972c2c5cc8173f701
https://doi.org/10.1002/art.11299
https://doi.org/10.1002/art.11299
Autor:
Cecil Chen, Erika Cochrane Elgin, Michele Fiscella, James W. Perry, Baiqin Teng, Thi-Sau Migone, Michael Bloom, Laurie Pukac, George A. Komatsoulis, Yun Mei, Kam H. Leung, Kimberly A. Florence, Binjun Liu, Thomas E. Kaufmann, Alice Concepcion, Steve Ruben, Chen Zhang, Guoxian Chen, Palanisamy Kanakaraj, Joe Zhou, Joelle C. Porter, Brian Mansfield, Ying Meng, Indra Sanyal, Viktor Roschke, Ricardo Cibotti
Publikováno v:
Nature Biotechnology. 21:302-307
A coordinated effort combining bioinformatic tools with high-throughput cell-based screening assays was implemented to identify novel factors involved in T-cell biology. We generated a unique library of cDNAs encoding predicted secreted and transmemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b83150c60ffff35798046ebd028b945
https://doi.org/10.1038/nbt797
https://doi.org/10.1038/nbt797
Autor:
Viktor Roschke, Hendrik Olsen, Courtney Vance, Ralph Alderson, Shiva Gohari-Fritsch, Kevin Connolly
Publikováno v:
Cancer Chemotherapy and Pharmacology. 50:202-212
Purpose. Repifermin (keratinocyte growth factor-2, KGF-2) is a growth factor that selectively induces epithelial cell proliferation, differentiation and migration. The objective of this study was to assess the effect of repifermin on in vitro tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42e2df1761f4830442ed8a8adc1df1f
https://doi.org/10.1007/s00280-002-0493-8
https://doi.org/10.1007/s00280-002-0493-8
Autor:
Dong Xu, William Stohl, Kimberly Labat, Fred R. Sattler, Dardo E. Ferrara, Gurtej S. Cheema, Svetlana Sosnovtseva, William Briggs, David M. Hilbert, Silvia S. Pierangeli, Viktor Roschke
Publikováno v:
Clinical Immunology. 104:115-122
To assess the helper T cell dependence of B lymphocyte stimulator (BLyS) protein-driven autoantibody production in vivo, serum levels of BLyS protein, total IgG, and anti-IgG anti-phospholipid (aPhL) autoantibodies from HIV-infected patients (n = 105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b881e83340f6e51367e8ca6fd10f2c
https://doi.org/10.1006/clim.2002.5238
https://doi.org/10.1006/clim.2002.5238